scholarly journals Evaluation of gender differences in patients with STEMI: clinical profile, risk factors burden, ischemia time, extent of coronary artery disease, primary PCI procedure outcomes, in hospital outcome, 30 day and 6 month outcome

2020 ◽  
Vol 72 ◽  
pp. S7
Author(s):  
Suman Sharma ◽  
Roopa Salwan ◽  
Rajeev Rathi ◽  
Mayank Gupta ◽  
Vamsi Merugumala
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Gender Differences ◽  
Coronary Artery ◽  
Clinical Profile ◽  
Primary Pci ◽  
Ischemia Time ◽  
Hospital Outcome ◽  
Artery Disease

Study on Clinical Profile and risk factors of Coronary Artery Disease in Indian Women

2018 ◽  
Vol 4 (2) ◽  
pp. 94-99
Author(s):  
Keshavamurthy Ganapathy Bhat ◽  
◽  
Krishnakumar Kanniyyappan ◽  
Bhupinder Kaur Anand ◽  
Marwaha Manvinder Pal Singh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Clinical Profile ◽  
Indian Women ◽  
Artery Disease

scholarly journals Diabetes mellitus and other cardiovascular risk factors in lower-extremity peripheral artery disease versus coronary artery disease: an analysis of 1,121,359 cases from the nationwide databases

2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Mitsuyoshi Takahara ◽  
◽  
Osamu Iida ◽  
Shun Kohsaka ◽  
Yoshimitsu Soga ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Coronary Artery Disease ◽  
Cardiovascular Risk ◽  
Coronary Artery ◽  
Lower Extremity ◽  
Cardiovascular Risk Factors ◽  
Clinical Profile ◽  
Peripheral Artery ◽  
Artery Disease

Abstract Background Lower-extremity peripheral artery disease (LE-PAD) and coronary artery disease (CAD) are both pathologically rooted in atherosclerosis, and their shared clinical features regarding the exposure to cardiovascular risk factors have been emphasized. However, comparative data of the two cardiovascular diseases (CVDs) were so far lacking. The purpose of this study was to directly compare the clinical profile between cases undergoing endovascular therapy (EVT) for LE-PAD and those undergoing percutaneous coronary intervention (PCI). Methods Data were extracted from the nationwide procedural databases of EVT and PCI in Japan (J-EVT and J-PCI) between 2012 and 2017. A total of 1,121,359 cases (103,887 EVT cases for critical limb ischemia [CLI] or intermittent claudication and 1,017,472 PCI cases for acute coronary syndrome [ACS] or stable angina) were analyzed. Heterogeneity in clinical profile between CVDs was evaluated using the C statistic of the logistic regression model for which dependent variable was one CVD versus another, and explanatory variables were clinical profile. When two CVDs were completely discriminated from each other by the developed model, the C statistic (discrimination ability) of the model would be equal to 1, indicating that the two CVDs were completely different in clinical profile. On the other hand, when two CVDs were identical in clinical profile, the developed model would not discriminate them at all, with the C statistic equal to 0.5. Results Mean age was 73.5 ± 9.3 years in LE-PAD patients versus 70.0 ± 11.2 years in CAD patients (P < 0.001). The prevalence of diabetes mellitus and end-stage renal disease was 1.96- and 6.39-times higher in LE-PAD patients than in CAD patients (both P < 0.001). The higher prevalence was observed irrespective of age group. The exposure to other cardiovascular risk factors and the likelihood of cardiovascular risk clustering also varied between the diseases. The between-disease heterogeneity in patient profile was particularly evident between CLI and ACS, with the C statistic equal to 0.833 (95% CI 0.831–0.836). Conclusions The current study, an analysis based on nationwide procedural databases, confirmed that patient profiles were not identical but rather considerably different between clinically significant LE-PAD and CAD warranting revascularization.

scholarly journals Gender Differences in South Indians with Premature Coronary Artery Disease (< 40 Years)—Insights from the PCAD Registry

2021 ◽  
Author(s):  
Laxmi H. Shetty ◽  
Rahul S. Patil ◽  
Jayashree Kharge ◽  
J. R. Vijay Kumar ◽  
Santu Ghosh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Gender Differences ◽  
Coronary Artery ◽  
Clinical Presentation ◽  
Premature Coronary Artery Disease ◽  
Coronary Risk Factors ◽  
Artery Disease ◽  
Conventional Risk Factors ◽  
Timely Treatment

Introduction Coronary artery disease (CAD) follows a different pattern in women and men, more so in the young (< 40 years). The gender differences in the risk factors, clinical presentation and diagnosis need to be understood, so that appropriate and timely treatment can be given. Objective The study contemplates to analyze the gender differences in the presence of major coronary risk factors, clinical presentation, diagnosis and immediate outcomes in patients who present with premature CAD (PCAD). Patients and Methods We evaluated 1,062 consecutive registry patients who presented with diagnosis of PCAD between 2018 to 2019 at our institution after satisfying the inclusion criteria. Results The study analyses 82 females and 980 males. The mean age of females was 35.4 ± 4.68 years and males was 34.2 ± 4.25 years. Males smoked more often (55.1%, p < 0.001). Females more often had abnormal BMI (84.1%, p < 0.001), increased waist-hip ratios (97.6%, p < 0.001), diabetes (35.4%, p < 0.001), dyslipidemia (17.1% vs. 11%) and hypertension (15.9% vs. 11.5%). STEMI was the most common presentation among males (80.4% vs. 71.9%). Majority of females (74.6%) presented 6 hours after index pain. NSTEMI was more common among females (20.7% vs. 16%). Single-vessel involvement was common in both sexes (84.1% in males and 85.2% in females). Obstructive CAD was less common in both groups. Conclusions Conventional risk factors play a major role for CAD in Indians. Smoking was common in males and metabolic syndrome in females. Also, females had a higher threshold for seeking treatment and referral. Measures have to be taken for early diagnosis and referral of females. Recanalized and thrombotic coronaries were common, indicating predominant thrombus burden in the young

scholarly journals Clinical Profile of Acute Coronary Syndrome

2021 ◽  
pp. 259-262
Author(s):  
Azeem Ahamed ◽  
N. Deepthi
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Acute Coronary Syndrome ◽  
Coronary Artery ◽  
Tobacco Use ◽  
Metabolic Disorders ◽  
Clinical History ◽  
Clinical Profile ◽  
Coronary Syndrome ◽  
Artery Disease

Background: In the developing world, coronary artery disease (CAD) is considered to be a leading source of illness and ultimately death. Indians are nowadays linked to a more dangerous variant of coronary artery disease (CAD) with a lower age of onset and is more common in men. Aim: To analyse the clinical profile of patients with ACS syndrome for the purpose of drawing predominance in demography, metabolic disorders and tobacco use. Materials and Methods: We enrolled 50 patients with characteristic ECG alterations and clinical history who were admitted to the emergency department between January and August 2021 in a prospective research at Saveetha Medical College and Hospital. Every patient had a predetermined Performa filled out, which included a full clinical history and investigation procedures. The clinical history disclosed details regarding the patient's age, gender, and risk factors. Results: On analysis, results were conclusive of male predominance probably accentuated by tobacco use, alcohol consumption and other metabolic disorders. Conclusion: With prevalence of risk factors on rise, younger individuals are also affected. Proper risk factor management will help in preventing Acute coronary syndrome.

scholarly journals STUDY OF CORONARY ARTERY DISEASE IN WOMEN– THE INCIDENCE OF RISK FACTORS AND CLINICAL PROFILE

2017 ◽  
Vol 6 (53) ◽  
pp. 4042-4047
Author(s):  
Thiagarajan Chakravarthi ◽  
Sappani Kasipandian ◽  
Pasupulati Venkatasamy Krishnan
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Clinical Profile ◽  
Artery Disease

scholarly journals CLINICAL PROFILE OF PATIENTS WITH CORONARY TORTUOSITY AND ITS RELATION WITH CORONARY ARTERY DISEASE

2018 ◽  
Author(s):  
Ankush Gupta ◽  
Prashant Panda ◽  
YASH SHARMA ◽  
Ashwin Mahesh ◽  
Prafull Sharma ◽  
...  
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Myocardial Ischemia ◽  
Chronic Stable Angina ◽  
Clinical Profile ◽  
Objective Evidence ◽  
Artery Disease ◽  
Coronary Tortuosity ◽  
Cad Risk

Background: Coronary tortuosity is a common angiographic finding. Scarce data is available on clinical profile of patients with coronary tortuosity (CT) and its relation with coronary artery disease (CAD). Method: A total 224 patients undergoing angiography for suspected CAD were included in the study. CT was defined by the presence of ≥3 consecutive bends of &gt; 45 degree measured at end-diastole in an epicardial artery ≥2 mm in diameter. CT was present in 45(20.08%) patients in the study and another 45 patients without CT was randomly selected as control (NCT group). Clinical profile of CT and NCT group was compared. Results: Incidence of CT was significantly higher in females (p=0.000) and hypertensives (p=0.001) patients. CT was most commonly seen in Left circumflex coronary artery. Incidence of CAD was significantly lower in CT group as compare to NCT group (0.02). Risk factors for CAD was associated with reduced incidence of CT. Majority (88.46%) patient with CT without CAD presented with chronic stable angina out of which (65.21%) had an objective evidence of myocardial ischemia. Conclusion: CT is more commonly seen females and hypertensive patients. It has negative correlation with CAD. Risk factors of CAD do not predict CT. CT itself can lead to myocardial ischemia.

scholarly journals Association of TIMI Risk Score with Angiographic Severity of Coronary Artery Diseases and In-Hospital Outcome in Patient with STEMI Undergoing Primary PCI

2018 ◽  
Vol 10 (2) ◽  
pp. 135-139
Author(s):  
Anup Kumar Howlader ◽  
Afzalur Rahman ◽  
Abdul Momen ◽  
Samir Kumar Kundu ◽  
Mohammad Khalilur Rahman Siddiqui ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Risk Score ◽  
Adverse Outcomes ◽  
Primary Pci ◽  
Hospital Outcome ◽  
Coronary Artery Disease Severity ◽  
Group I ◽  
Artery Disease ◽  
Timi Risk Score

Background: The Thrombolysis In Myocardial Infarction (TIMI) risk score was developed as a bedside tool to stratify STEMI patients eligible for reperfusion by their mortality risk. The TIMI risk score has shown to provide good discrimination in predicting mortality at 30 days and even up to 365 days.Methods: By purposive sampling a total of 64 consecutive patients were considered. Coronary artery disease severity was assessed by Vessels Score. The in-hospital adverse outcomes looked for were heart failure, cardiogenic shock, ventricular arrhythmia, re-infarction, stroke and death. Study subject was divided into two groups on the basis of TIMI risk score. In group I - patients with low TIMI risk score (0- 4); in group II - Patients with high TIMI risk score (≥5).Results: Multi vessel involvement were less in low TIMI group 1 (3.1%) but much greater (p<0.05) in high TIMI group 9 (28.1%). Adverse outcome was present 10(31.3%) in high TIMI group and 2(6.3%) in low TIMI group (p=0.01).Conclusion: High TIMI risk score was associated with more adverse in hospital outcome in patients with STEMI who underwent primary PCI. This study also demonstrated that the TIMI risk score carried a significant positive correlation with the coronary artery disease severity.Cardiovasc. j. 2018; 10(2): 135-139

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