Kuttner’s tumour: chronic sclerosing sialadenitis- a mimicker of malignancy

Background: Kuttner’s tumour is a condition of the submandibular gland which is underreported as a distinct entity. Also called as the chronic sclerosing sialadenitis it resembles a plasmocytic and lymphocytic inflammatory process and presents as a hard and painful mass which clinically mimics a malignancy and raises significant concerns. The objective of the present study was to evaluate cases of Kuttner’s tumor and discuss its clinical and pathological aspects to distinguish it from a definite malignancy and create a grown acceptance of the presence of such an entity in our setting.Methods: We collected 170 cases of submandibular swellings and evaluated in detail the clinical and pathological aspects of eight cases out of them which were later diagnosed to as Kuttner’s tumour.Results: The age of the patients varied between 23 to 61 years (mean age 42.5 years) with 3 males and 5 females. 6 patients reported with a firm to hard painless submandibular mass (5 left sided; 3 right sided) while 2 patients experienced intermittent discomfort. The mean duration of presentation of symptoms was 5.3 months. Fine needle aspiration cytology was done in 6 cases preoperatively. Following submandibular sialadenectomy histopathology showed salivary gland tissue with preserved lobular architecture, but with marked fibrosis, acinar atrophy, and a dense lymphoplasmacytic infiltrates.Conclusions: Kuttner’s tumor may be pre operatively distinguished from a malignancy with improved imaging and a good image guided FNA Cytology saving the clinician and the patient from a lot of dilemma. However, histopathology and immunohistochemistry would be the key in establishing the diagnosis.

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A case report of 29 year old male patient with breast carcinoma: diagnosed on fine needle aspiration cytology

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20195938 ◽

2019 ◽

Vol 8 (1) ◽

pp. 375

Author(s):

Komal Patel ◽

Pallavi Chaudhri ◽

Siddhi M. Patel

Keyword(s):

Breast Cancer ◽

Fine Needle Aspiration ◽

Histopathological Examination ◽

Needle Aspiration ◽

Male Breast ◽

Breast Cancers ◽

Aspiration Cytology ◽

Fine Needle ◽

The Mean ◽

Needle Aspiration Cytology

Breast cancer has been considered a female dominated disease. Carcinoma of male breast is a rare disease representing 1% of all breast cancers and less than 1 % of all cancers in men. The mean age at presentation is mainly in sixties. We here present a case of male breast cancer presented at very young age of 29 years, diagnosed on fine needle aspiration which was confirmed later on histopathological examination.

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Küttner's tumor of the submandibular glands: Report of five cases with fine-needle aspiration cytology

Diagnostic Cytopathology ◽

10.1002/dc.20505 ◽

2006 ◽

Vol 34 (9) ◽

pp. 631-635 ◽

Cited By ~ 11

Author(s):

Sadayuki Kaba ◽

Masaru Kojima ◽

Hazuki Matsuda ◽

Shiro Sugihara ◽

Nobuhide Masawa ◽

...

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Fine Needle ◽

Submandibular Glands ◽

Needle Aspiration Cytology ◽

Küttner’S Tumor

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Efficacy of Sonoelastography Images in Solitary Cold Thyroid Nodule and Compared with Fine Needle Aspiration Cytology Findings (FNAC)

Bangladesh Journal of Nuclear Medicine ◽

10.3329/bjnm.v19i2.35914 ◽

2018 ◽

Vol 19 (2) ◽

pp. 103 ◽

Cited By ~ 1

Author(s):

Jasmin Ferdous ◽

Mahbub Ur Rahman ◽

Hosne Ara Rahman ◽

Jamiul Hossain ◽

Samira Sharmin ◽

...

Keyword(s):

Thyroid Nodule ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Ultrasound Elastography ◽

Aspiration Cytology ◽

Predictive Values ◽

Fine Needle ◽

The Mean ◽

Needle Aspiration Cytology

Objective: To evaluate the validity of sonoelastography of cold thyroid nodule in diagnosis of malignant nodule with fine needle aspiration cytology analysis as the reference standard.Patients and Methods: This cross sectional study was conducted in the Institute of Nuclear Medicine & Allied Sciences (INMAS), Sir Salimullah Medical College (SMC) & Mitford Hospital campus, Dhaka, from July 2015 to June 2016 in 85 patients with solitary solid cold nodule. Eighty five nodules in these patients were examined by conventional ultrasound, ultrasound elastography and radionuclidescan. The final diagnosis was obtained from cytological findings. Tissue stiffness on ultrasound elastography was scored from 1 (low stiffness over the entire nodule) to 4 (high stiffness over the entire nodule).Results: The mean age was found 33.8±10.1 years with range from 12 to 58 years and male to female ratio was 1:5.1. The mean size of nodules was found 2.0±0.6 cm. Most (40.0%) of the patients were found in elastography score 2, 22(25.9%) score 1, 17(20.0%) score 4 and 12(14.1%) score 3. The validity of elastography scores had sensitivity 77.8%, specificity 86.2%, accuracy 83.5%, positive predictive values 72.4% and negative predictive values 89.3% for prediction of thyroid nodule.Conclusion: Considering the validity parameter the elastography may be effective diagnostic modality for evaluation of thyroid nodule.Bangladesh J. Nuclear Med. 19(2): 103-106, July 2016

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Phantom Nodules Detected by Ultrasound Examination of the Neck: The Possibility of Ectopic Cervical Thymic Tissue in Adults

Ultrasound International Open ◽

10.1055/a-0747-6453 ◽

2018 ◽

Vol 4 (04) ◽

pp. E119-E123 ◽

Cited By ~ 1

Author(s):

Hisashi Ota ◽

Mitsuyoshi Hirokawa ◽

Ayana Suzuki ◽

Maki Oshita ◽

Aki Ito ◽

...

Keyword(s):

Adipose Tissue ◽

Ultrasound Examination ◽

Needle Aspiration ◽

Surrounding Tissue ◽

Aspiration Cytology ◽

Thymic Tissue ◽

Neck Lymph Node ◽

Vascular Flow ◽

The Mean ◽

Needle Aspiration Cytology

Abstract The aim of this study was to investigate the ultrasound characteristics and clinical significance of slightly hyperechoic lesions, referred to as phantom nodules, in the perithyroidal area in patients. A total of 128 patients who underwent thyroidectomy with central neck lymph node dissection at Kuma Hospital in Hyogo, Japan were included in the study. We detected 16 phantom nodules during preoperative ultrasound examinations, defined as slightly hyperechoic masses located in the perithyroidal areas, in 13 of these 128 patients (10.2%; mean age: 55.6 years, range: 36–75 years).All phantom nodules were located in the caudal region of the thyroid gland, and the mean maximum dimension was 7.2 mm. 12 of the 16 nodules were round or oval, while the remaining 4 were fusiform and molded by the surrounding tissue. All nodules were well-defined, solid, homogeneous, hyperechoic masses. No speckled echo pattern, internal linear echo, or vascular flow signal was observed. All 4 nodules subjected to histological examination were composed of ectopic thymic tissue. In 2 of these 4, the parenchyma was severely involuted and almost entirely replaced by adipose tissue. To the best of our knowledge, this is the first report wherein some of the detected hyperechoic perithyroidal masses were composed of ectopic thymic tissue, and some were primarily composed of adipose tissue that completely replaced involuted ectopic thymic tissue. The results of the study suggest that these so-called phantom nodules are clinically insignificant and do not require fine needle aspiration cytology or further investigation.

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Incidence of malignancy in solitary thyroid nodules

The Journal of Laryngology & Otology ◽

10.1017/s0022215115000882 ◽

2015 ◽

Vol 129 (7) ◽

pp. 677-681 ◽

Cited By ~ 6

Author(s):

S M Keh ◽

S K El-Shunnar ◽

T Palmer ◽

S F Ahsan

Keyword(s):

Thyroid Surgery ◽

High Probability ◽

Thyroid Nodules ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Fine Needle ◽

Malignancy Rate ◽

The Mean ◽

Needle Aspiration Cytology ◽

High Index Of Suspicion

AbstractObjectives:This study aimed to investigate the prevalence and clinical significance of solitary thyroid nodules in patients who underwent thyroid surgery.Methods:A retrospective review was performed of the case notes of all adult patients who underwent thyroid surgery from January 2003 to December 2009. All patients with solitary thyroid nodules identified by ultrasonography were included.Results:In total, 225 patients underwent thyroid surgery. The prevalence of solitary thyroid nodules was 27.1 per cent (61 out of 225 patients). Seventy-two per cent of patients were women and the mean age at presentation was 52 ± 16 years. In all, 75.4 per cent of solitary nodules had neoplastic pathology and the malignancy rate was 34.4 per cent. The sensitivity and specificity of fine needle aspiration cytology for neoplasm detection were 73.9 per cent and 80.0 per cent, respectively. There was no association between the various ultrasonography parameters and malignancy risk (p > 0.05).Conclusion:Solitary thyroid nodules should be investigated thoroughly with a high index of suspicion because there is a high probability (34.0 per cent) of malignancy.

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Clinical and Morphological Spectrum of Histoplasmosis on Cytology Along with the Review of Literature

Acta Cytologica ◽

10.1159/000509151 ◽

2020 ◽

Vol 64 (6) ◽

pp. 532-538

Author(s):

Gargi Kapatia ◽

Ashmita Saha ◽

Manish Rohilla ◽

Parikshaa Gupta ◽

Nalini Gupta ◽

...

Keyword(s):

Fine Needle Aspiration ◽

Giant Cells ◽

Needle Aspiration ◽

Review Of Literature ◽

Aspiration Cytology ◽

Female Ratio ◽

Fine Needle ◽

The Mean ◽

Needle Aspiration Cytology ◽

Male To Female

Objective: The aim of the study was to study the clinical and morphological spectrum of histoplasmosis diagnosed by fine needle aspiration cytology (FNAC). Study Design: A total of 17 patients diagnosed with histoplasmosis on FNAC were studied over a period of 5 years. The cytology smears were studied and analysed for the cytomorphological spectrum of histoplasmosis. Results: Among the 17 patients studied, the mean age was 51.3 years (range 6–84 years). Male-to-female ratio was 3.25:1 with 4 females and 13 males. The frequent sites of involvement were the lung (5), lymph node (4), adrenal gland (4), and skin (4). The most common cytological patterns were histiocytic collection, followed by granulomas and multinucleated giant cells. Necrosis was noted in only 4 cases. Conclusion: Fine needle aspiration is a highly accurate, rapid, and cheap technique for the diagnosis of histoplasmosis due to its distinct morphological features.

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Adequacy of Cytologic Samples by Ultrasound-Guided Percutaneous Transthoracic Fine-Needle Aspiration Cytology of Peripheral Pulmonary Nodules for Morphologic Diagnosis and Molecular Evaluations: Comparison With Computed Tomography–Guided Percutaneous Transthoracic Fine-Needle Aspiration Cytology

Archives of Pathology & Laboratory Medicine ◽

10.5858/arpa.2018-0346-oa ◽

2019 ◽

Vol 144 (3) ◽

pp. 361-369 ◽

Cited By ~ 1

Author(s):

Immacolata Cozzolino ◽

Andrea Ronchi ◽

Gaetana Messina ◽

Marco Montella ◽

Floriana Morgillo ◽

...

Keyword(s):

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Pulmonary Nodules ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Ct Guided ◽

Fine Needle ◽

The Mean ◽

Needle Aspiration Cytology ◽

Mean Time

Context.— Fine-needle aspiration cytology (FNAC) of pulmonary nodules is usually guided by computed tomography (CT), whereas ultrasonography (US) is generally considered not applicable for such purposes. Objective.— To evaluate the clinical applicability and diagnostic utility of US-guided transthoracic FNAC of peripheral pulmonary nodules. Design.— Ultrasonography-guided transthoracic FNAC was obtained from 40 selected patients with peripheral, subpleural, and paravertebral pulmonary nodules. Air-dried and Diff-Quik–stained smears were used for rapid on-site evaluation; additional smears were alcohol fixed for Papanicolaou staining. Cell blocks were set up for immunocytochemical and molecular studies; in 2 cases, a flow cytometry evaluation was also performed. The series was compared to 40 CT-guided pulmonary FNAC samples from patients with pleural, peripheral, and paravertebral pulmonary nodules, to evaluate differences in terms of diagnostic rate, time of execution, safety, and cost. Results.— The US-guided FNAC samples had results that were adequate and representative in 95% of cases. No significant differences were observed between the 2 groups in terms of diagnostic rate, number of passes, and cellularity of both smears and cell blocks. The mean time needed for the execution of US-guided FNAC was 13.1 minutes, whereas the mean time for CT-guided FNAC was 23.6 minutes. Thus, US-guided FNAC was significantly more rapid than CT-guided pulmonary FNAC. Because pneumothorax occurred in 1 individual who underwent US-guided FNAC and in 9 who underwent CT-guided FNAC, we might conclude that US-guided FNAC is a significantly safer procedure. Finally, comparing the costs of both procedures, US-guided FNAC is less expensive. Conclusions.— Our experience showed an elevated clinical applicability and diagnostic utility of US-guided transthoracic FNAC for selected pulmonary nodules.

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Role of Fine Needle Aspiration Cytology in the Diagnosis of Parotid Gland Tumors: Analysis of 193 Cases

International Archives of Otorhinolaryngology ◽

10.1055/s-0040-1709111 ◽

2020 ◽

Vol 24 (04) ◽

pp. e508-e512

Author(s):

Rahim Dhanani ◽

Haissan Iftikhar ◽

Muhammad Sohail Awan ◽

Nida Zahid ◽

Sehrish Nizar Ali Momin

Keyword(s):

Parotid Gland ◽

Diagnostic Accuracy ◽

Fine Needle Aspiration ◽

Fine Needle Aspiration Cytology ◽

Needle Aspiration ◽

Aspiration Cytology ◽

Fine Needle ◽

Parotid Gland Tumors ◽

The Mean ◽

Needle Aspiration Cytology

Abstract Introduction Parotid gland tumors include a wide variety of inflammatory and neoplastic diseases. The majority of these tumors are benign (80%), which usually require superficial parotidectomy, while the incidence of malignant tumors is lower (20%), requiring more radical surgery with or without neck dissection. The diagnosis cannot be established on the basis of clinical history and simple physical examination and requires complementary diagnostic methods. Fine needle aspiration cytology (FNAC) guided by ultrasound is a widely used diagnostic tool to evaluate parotid swellings. Objective To determine the sensitivity, specificity, positive and negative predictive values and diagnostic accuracy of FNAC in the diagnosis of parotid gland tumors. Methods A retrospective chart review of 193 patients who underwent preoperative FNAC and parotidectomy at the Aga Khan University Hospital, Karachi, Pakistan, from the period of January 2000 to December 2015 was performed. Results Out of 193 patients undergoing parotidectomy, 110 (57%) were males and 83 (43%) were females, the mean age being 48.21 and 43.76 years old, respectively. The mean duration of the symptoms was 41.33 months, and the most common symptom was preauricular swelling present in all patients, followed by pain, which was present in 29 patients (15%) and facial nerve weakness in 6 patients (3.1%). Fine needle aspiration cytology was performed preoperatively and the results were compared with the final histopathology, which showed sensitivity of 88.9%, specificity of 97.9%, positive predictive value of 93%, negative predictive value of 96.7% and diagnostic accuracy of 95.8%. Conclusion Our results suggest that FNAC is relatively an accurate method for preoperative diagnosis of parotid swelling and can prove to be a valuable tool for preoperative counseling of the nature of the disease and prognosis.

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Pleomorphic Adenoma Originating from Heterotopic Salivary Tissue of the Upper Neck: A Diagnostic Pitfall

Case Reports in Otolaryngology ◽

10.1155/2017/5767396 ◽

2017 ◽

Vol 2017 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Riccardo La Macchia ◽

Salvatore Stefanelli ◽

Vincent Lenoir ◽

Nicolas Dulguerov ◽

Jean-Claude Pache ◽

...

Keyword(s):

Salivary Gland ◽

Thyroid Nodule ◽

Pleomorphic Adenoma ◽

Histopathological Examination ◽

Metastatic Lymph Node ◽

Needle Aspiration ◽

Diagnostic Pitfall ◽

Salivary Gland Tissue ◽

Gland Tissue ◽

Needle Aspiration Cytology

Pleomorphic adenoma directly arising in the neck is thought to originate from heterotopic salivary gland tissue. In this article, we present the case of a 55-year-old female patient with a histologically proven pleomorphic adenoma located at the left mandibular angle, anteriorly to the sternocleidomastoid muscle and posteroinferiorly to the submandibular gland. As the patient also had an ipsilateral thyroid nodule with coarse calcifications, clinical and radiological features suggested a possible level II metastatic lymph node. However, ultrasound-guided fine needle aspiration cytology and postsurgery histopathological examination revealed a pleomorphic adenoma arising from heterotopic salivary gland tissue unrelated to a benign thyroid nodule. In this article, we provide a review of the existing literature on heterotopic salivary gland tissue and related neoplasms and discuss their imaging presentation.

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