scholarly journals The effect of peroperative erythrocyte transfusion on infectious complications in patients with gastric cancer undergoing curative gastrectomy

2021 ◽  
Vol 8 (2) ◽  
pp. 503
Author(s):  
Ahmet Sencer Ergin ◽  
Ogün Erşen ◽  
Ümit Mercan ◽  
Cemil Yüksel ◽  
Salim Demirci
Keyword(s):  
Gastric Cancer ◽  
Blood Transfusion ◽  
Surgical Site Infection ◽  
Infectious Complications ◽  
Site Infection ◽  
Curative Surgery ◽  
Curative Gastrectomy ◽  
Infection Incidence ◽  
Surgical Site Infection Incidence ◽  
Anastomosis Leakage

Background: In this study, the effect of perioperative blood transfusion on infectious complications in patients undergoing curative surgery for gastric adenocarcinoma was investigated.Methods: The clinicopathological results of 312 patients who underwent curative gastrectomy were retrospectively analyzed. The effect of blood transfusion on the development of postoperative infectious complications were statistically analyzed.Results: In the subgroup of patients with intraoperative transfusion, surgical site infection incidence was found to be significantly higher in patient with 2U above ES transfusions. (p=0.014). In the subgroup of patients with postoperative transfusion, hospital stay (p<0.001), postoperative CRP values (p<0.001), surgical site infection incidence (p=0.049) and anastomosis leakage incidence (p<0.001) were found to be significantly higher in patient with 2U above ES transfusions. In the subgroup of patients with both intraoperative and postoperative transfusion, SSI, anastomotic leakage and any infective complication incidences were found to be significantly higher in patients with 2U and above transfusions. In multivariate analysis, age (p=0.015), BMI (p=0.011), intraoperative transfusion (p=0.011) and both intraoperative and postoperative transfusion (p=0.045) were found to be independent risk factors for infective complications.Conclusions: It was found that performing peroperative ES transfusion is associated with increased rates of infectious complications in patients undergoing curative gastrectomy for gastric cancer by causing immunomodulation.

Surgical site infection: Incidence and impact on hospital utilization and treatment costs

2009 ◽  
Vol 37 (5) ◽  
pp. 387-397 ◽  
Author(s):  
Gregory de Lissovoy ◽  
Kathy Fraeman ◽  
Valerie Hutchins ◽  
Denise Murphy ◽  
David Song ◽  
...  
Keyword(s):  
Surgical Site Infection ◽  
Treatment Costs ◽  
Hospital Utilization ◽  
Site Infection ◽  
Infection Incidence ◽  
Surgical Site Infection Incidence

Reducing surgical site infection incidence through a network: results from the French ISO-RAISIN surveillance system

2009 ◽  
Vol 72 (2) ◽  
pp. 127-134 ◽  
Author(s):  
P. Astagneau ◽  
F. L'Hériteau ◽  
F. Daniel ◽  
P. Parneix ◽  
A.-G. Venier ◽  
...  
Keyword(s):  
Surgical Site Infection ◽  
Surveillance System ◽  
Site Infection ◽  
Infection Incidence ◽  
Surgical Site Infection Incidence

scholarly journals Abdominal Surgical Site Infection Incidence and Risk Factors in a Mexican Population

2019 ◽  
Vol 32 (6) ◽  
pp. 1-6
Author(s):  
Crystell Guzmán-García ◽  
Oscar I. Flores-Barrientos ◽  
Isela E. Juárez-Rojop ◽  
Julio C. Robledo-Pascual ◽  
Manuel A. Baños-González ◽  
...  
Keyword(s):  
Risk Factors ◽  
Surgical Site Infection ◽  
Mexican Population ◽  
Site Infection ◽  
Infection Incidence ◽  
Surgical Site Infection Incidence

scholarly journals PIN36 Surgical Site Infection Incidence and Burden Assessment Using Multi-Institutional Real-World Data

2011 ◽  
Vol 14 (7) ◽  
pp. A271-A272
Author(s):  
G. Delissovoy ◽  
F. Pan ◽  
A.D. Patkar ◽  
C.E. Edmiston ◽  
S. Peng
Keyword(s):  
Surgical Site Infection ◽  
Real World ◽  
Site Infection ◽  
Real World Data ◽  
World Data ◽  
Infection Incidence ◽  
Surgical Site Infection Incidence

scholarly journals Identification of Predictors of Surgical Site Infection in Patients With Gastric Cancer Undergoing Surgery With Curative Intent

2017 ◽  
Vol 102 (3-4) ◽  
pp. 157-164 ◽  
Author(s):  
Yuji Toiyama ◽  
Tadanobu Shimura ◽  
Hiromi Yasuda ◽  
Shigeyuki Yoshiyama ◽  
Susumu Saigusa ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Serum Albumin ◽  
Surgical Site Infection ◽  
Operation Time ◽  
Albumin Concentration ◽  
Site Infection ◽  
Curative Surgery ◽  
Neutrophil Lymphocyte Ratio ◽  
Preoperative Serum ◽  
Duration Of Surgery

Surgical site infection (SSI) is a potentially morbid and costly complication of surgery. The purpose of this study was to determine preoperative and operative predictors of SSIs after gastric resection with lymphadenectomy in patients with gastric cancer (GC). Data on clinicopathologic factors, including operative and preoperative laboratory factors, for 384 patients with GC who had undergone curative surgery were analyzed in this retrospective study to assess their associations with SSIs. Superficial/deep incisional SSIs (iSSIs) and organ/space SSIs (o/sSSIs) occurred in 18 (4.6%), and 27 (7.0%), respectively. The o/sSSIs were significantly associated with surgery-related factors such as duration of operation, blood loss, and extent of tumor. Additionally, high levels of preoperative indicators of systemic inflammation, including neutrophil counts, neutrophil/lymphocyte ratio, and C-reactive protein concentrations, were significantly associated with o/sSSIs. Multivariate analyses demonstrated that preoperative neutrophil counts and duration of surgery were independent predictors for o/sSSIs, whereas only preoperative serum albumin concentration was predicted for iSSIs. In patients with GC undergoing curative surgery, preoperative neutrophil count and operation time are potentially valuable predictors of o/sSSIs, whereas only preoperative serum albumin predicts iSSIs.

scholarly journals Evaluation of underreported surgical site infection evidenced by post-discharge surveillance

2007 ◽  
Vol 15 (5) ◽  
pp. 992-997 ◽  
Author(s):  
Adriana Cristina de Oliveira ◽  
Daclé Vilma Carvalho
Keyword(s):  
Prospective Study ◽  
Surgical Site Infection ◽  
Digestive System ◽  
Site Infection ◽  
Post Discharge ◽  
General Hospitals ◽  
Infection Incidence ◽  
Surgical Site Infection Incidence ◽  
Digestive System Surgery ◽  
The Impact

The Surgical Site Infection (SSI) has been pointed as one of the most important infection sites. This study aimed to determine the surgical site infection incidence during hospitalization and the impact of notification after discharge through two methods. This prospective study was carried out in the digestive system surgery service (DSS) of two general hospitals of São Paulo, in the period from August, 2001 to March, 2002. Incidence levels of 6.7% and 4.5% were notified in the institutions A and B respectively. The incidence of SSI after discharge in the institution A was 27% and 13.4% in the institution B. Surveillance after discharge evidenced global rates of 33.7% and 17.9% for institutions A and B respectively. The rates of infection increased 5.02 and 3.98 times respectively in institutions A and B.

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