Incidence and profile of Helicobacter pylori infection among HIV positive patients

Background: People having HIV infection present with a number of symptoms related to gastrointestinal tract like dyspepsia. HIV itself as well as opportunistic infections is responsible for such symptoms. Notably is Helicobacter pylori infection causes variety of such symptoms. The objective of the present research was to study incidence and profile of Helicobacter pylori among HIV positive patients.Methods: A hospital based cross sectional study was carried out over a period of two years among 101 HIV positive patients in the Department of General Medicine, Madurai Medical College, Madurai in collaboration with Department of Medical Gastroenterology and also Department of Venereology and Leporology. Rapid urease test was done. HIV status was confirmed by ELISA test. Data was analysed with the help of EPI statistical software.Results: Majority (40.6%) had CD4 count of 200-500. It has been observed that incidence of Helicobacter pylori was low in groups with low CD4 count. It was also observed that those with higher CD4 count had higher incidence of RUT positivity. This association was found to be statistically significant. The incidence of Helicobacter pylori positivity was not significantly different among those patients who were on ART (18%) and those who were not on ART (21%).Conclusions: The incidence of Helicobacter pylori infection was less in HIV positive patients. Those with CD4 cell count less than 100 had lower incidence of Helicobacter pylori infection than those with CD 4 cell count more than 500. Incidence of Helicobacter pylori infection was not affected by ART.

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Serum pepsinogen and gastrin levels in HIV-positive patients: relationship with CD4+ cell count and Helicobacter pylori infection

Alimentary Pharmacology & Therapeutics ◽

10.1046/j.1365-2036.2002.01234.x ◽

2002 ◽

Vol 16 (4) ◽

pp. 807-811 ◽

Cited By ~ 8

Author(s):

P. Fabris ◽

A. Pilotto ◽

L. Bozzola ◽

G. Tositti ◽

G. Soffiati ◽

...

Keyword(s):

Helicobacter Pylori ◽

Cell Count ◽

Helicobacter Pylori Infection ◽

Hiv Positive ◽

Serum Pepsinogen ◽

Cd4 Cell Count ◽

Cd4 Cell

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Utility of Rapid urease test in diagnosis of Helicobacter pylori infection

International Journal Of Medical Science And Clinical Invention ◽

10.18535/ijmsci/v6i4.05 ◽

2019 ◽

pp. 4417-4422

Author(s):

Shaan Khetrapal ◽

Samarth Shukla ◽

Safia Rana ◽

Zeeba S Jairajpuri ◽

Sourya Acharya

Keyword(s):

Helicobacter Pylori ◽

Cross Sectional Study ◽

Helicobacter Pylori Infection ◽

Rapid Urease Test ◽

Cross Sectional ◽

Intestinal Lesions ◽

Common Diagnosis ◽

Urease Test ◽

H Pylori ◽

Haematoxylin And Eosin Stain

Aim: To evaluate the role of rapid urease test in diagnosis of Helicobacter pylori infection in various gastro intestinal lesions vis a vis conventional and special staining methods. Materials & Methods: This hospital based cross sectional study was conducted on 50 cases with gastro intestinal lesions. The obtained biopsies were then subjected to rapid urease test for detection of H. pylori by using the Pronto Dry Kit immediately. Further histopathology examination using conventional H & E (haematoxylin and eosin) stain and special Gimenez stain for H. pylori was done. Results: In this study gender wise distribution of patients showed 58% males and 42% females. Chronic gastritis was found to be the most common diagnosis (28%), followed by squamous cell carcinoma (20%) chronic inflammation (16%), H. pylori gastritis and adenocarcinoma stomach (6%), adenocarcinoma esophagus, dysplasia, erosion, esophagitis and perforation in 4%. Least common diagnosis was atrophic gastritis and carcinoid in 2%. We found that 26 cases were positive for H. pylori with Rapid urease test and 24 with special stain (Gimenez). Conclusion: This study amalgamates and incorporates the valuable clinical assessment along with the endoscopic findings, the surgical pathological (histopathology) evaluation of the biopsies along with the proto dry kit (rapid urease test), as a kind of “Gastric Triple Test” for declaring the patients as positive or negative for pathogenic infection with Helicobacter pylori.

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Efficacy of Helicobacter pylori eradication therapy among HIV positive and HIV negative individuals in Central Ethiopia and effects on CD4 cell count and haemoglobin levels

10.26226/morressier.5aeaf2d35800a00019098021 ◽

2018 ◽

Author(s):

Torsten Feldt ◽

Million Getachew Mesfun

Keyword(s):

Helicobacter Pylori ◽

Cell Count ◽

Eradication Therapy ◽

Hiv Positive ◽

Helicobacter Pylori Eradication ◽

Cd4 Cell Count ◽

Central Ethiopia ◽

Cd4 Cell ◽

Helicobacter Pylori Eradication Therapy ◽

Hiv Negative

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Assessment of Markers of Depression and CD4 Cell Count among Adult HIV-Positive Patients on Anti-Retroviral at a Nigerian University Teaching Hospital

Research Journal of Health Sciences ◽

10.4314/rejhs.v8i4.8 ◽

2020 ◽

Vol 8 (4) ◽

pp. 283-290

Author(s):

A. Amoko ◽

P.O. Ajiboye ◽

F.A. Olagunju ◽

R.O. Shittu

Keyword(s):

Family Medicine ◽

Cell Count ◽

Teaching Hospital ◽

Cd4 Count ◽

Hiv Positive ◽

P Value ◽

People Living With Hiv ◽

Cd4 Cell Count ◽

Prevalence Of Depression ◽

Cd4 Cell

Objective: Depression is a common mental health problem among people living with HIV/AIDS (PLWHA); because low count of lymphocytes with cluster of differentiation 4 (CD4 cell count) is associated with severe symptoms of HIV infection, there are thoughts that low CD4 cells count can provoke depressive illness. This study was conducted to determine the relationship between CD4 count and depression among adult HIV positivepatients attending Family Medicine clinics at University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria.Method: A hospital based descriptive cross-sectional study was done over a period of 6 months among 350 systematically randomly selected adult HIV-positive patients. PHQ-9 was used to obtain information on depression and the CD4 count was determined using a flow-cytometric method. Data were obtained and analyzed using SPSS-17. Chi-square was used to determine degree of association between the depression and the level of CD4 count. P-value of < 0.05 was considered statistically significant.Results: The prevalence of depression among the respondents was 33.4%. The prevalence of depression was highest among respondents with low CD4 count (≤349cells/ul), 37.0%, and least among those with high CD4 count (≥500cells/ul), 28.3%. This relationship was however not statistically significant.Conclusion: The overall prevalence of depression was high among the respondents (33.4%) suggesting the need for routine depression screening among HIV positive patients. There was no statistically significant association between presence of depression and level of CD4 count (p-value=0.302). Keywords: Depression, CD4count, PLWHA, Family Medicine, UITH.

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Association of gastric infection and periodontal disease through Helicobacter pylori as a common denominator: A systematic review and meta-analysi

10.37766/inplasy2021.10.0097 ◽

2021 ◽

Author(s):

Nansi López-Valverde ◽

◽

Antonio López-Valverde ◽

Ana Suarez ◽

Bruno Macedo de Sousa ◽

...

Keyword(s):

Systematic Review ◽

Helicobacter Pylori ◽

Clinical Studies ◽

Periodontal Diseases ◽

Meta Analysis ◽

Helicobacter Pylori Infection ◽

Enzyme Linked Immunosorbent Assay ◽

Rapid Urease Test ◽

Common Denominator ◽

Urease Test

Review question / Objective: Is gastric helicobacter pylori infection related to periodontal diseases? Condition being studied: Therefore, the aim of this systematic review and meta-analysis was to identify and analyze clinical studies to determine the direct correlation between Helicobacter Pylori gastric infection andPeriodontal Disease. Study designs to be included: Clinical studies that provided data on Helicobacter Pylori infection in both the stomach and oral cavity, confirmed by polymerase chain reaction (PCR), rapid urease test (RUT) or enzyme-linked immunosorbent assay (ELISA). Clinical studies that associated PD with Helicobacter Pylori. The diagnosis of PD was confirmed ac-cording to the diagnostic criteria in periodontology.

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