scholarly journals Oto acoustic emissions in early detection of sensorineural hearing loss in high-risk neonates

2021 ◽  
Vol 7 (11) ◽  
pp. 1794
Author(s):  
J. Ramanjaneyulu ◽  
S. Rajesh Kumar ◽  
V. Krishna Chaitanya ◽  
A. Kusumanjali
Keyword(s):  
Hearing Loss ◽  
High Risk ◽  
Early Detection ◽  
Sensorineural Hearing Loss ◽  
Brain Stem ◽  
Sensitivity And Specificity ◽  
Acoustic Emissions ◽  
Otoacoustic Emission ◽  
Auditory Neuropathy ◽  
Sensorineural Hearing

<p><strong>Background: </strong>Early identification of congenital hearing loss and early intervention ameliorated many adverse consequences. This study was performed to observe effectiveness of otoacoustic emission in screening of hearing loss in high-risk babies.</p><p><strong>Methods: </strong>Prospective study on 45 high-risk newborns delivered during period of 2013-2014. Selective newborn hearing performed with oto acoustic emissions (OAE) and auditory brain stem responses (ABR), in high-risk infants aged below 7 days, 15 days, after 45 days and after 90 days.</p><p><strong>Results: </strong>Study population comprised of 45 high-risk newborns. In 1<sup>st</sup> level screening, 28 (62%) babies showed recordable OAE, 17 (38%) babies failed. In 2<sup>nd</sup> level screening 31 (81%) passed and 7 (19%) failed and death occurred in 7 infants. In 3<sup>rd</sup> level screening both OAE and brain stem evoked response audiometry (BERA), was performed in 38 cases and positivity was reported in 37 cases. 4<sup>th</sup> level screening was similar to 3<sup>rd</sup> level screening where 3 babies failed ABR test. In our study incidence of sensorineural hearing loss found to be 78.91% (3/38×1000) per 1000 high-risk babies. Auditory neuropathy was observed in 2 (4.4%) patients. Sensitivity and specificity of OAE was 100% and 33.3% respectively. In high-risk low birth weight neonates’ sensitivity and specificity was 66.7% and 50.0%.</p><p><strong>Conclusions: </strong>In high-risk babies, appropriate time for screening with OAE is around 60 days of age. OAE are useful diagnostic tool in evaluation of high-risk neonates for early detection of sensorineural hearing loss.</p>

A Smartphone-Based Weber Test May Discriminate between a Conductive and a Sensorineural Hearing Loss

2019 ◽  
Vol 24 (4) ◽  
pp. 191-196
Author(s):  
Omer J. Ungar ◽  
Ophir Handzel ◽  
Oren Cavel ◽  
Yahav Oron
Keyword(s):  
Emergency Department ◽  
Hearing Loss ◽  
Clinical Study ◽  
Sensorineural Hearing Loss ◽  
Sensitivity And Specificity ◽  
Tuning Fork ◽  
Conductive Hearing Loss ◽  
Sensorineural Hearing ◽  
Unilateral Hearing Loss ◽  
Conductive Hearing

Objective: The aim of this paper was to compare the accuracy of a smartphone-based Weber test (SPWT) with the traditional tuning fork Weber test (TFWT) in identifying and differentiating between sensorineural hearing loss (SNHL) and conductive hearing loss (CHL). Study Design: We conducted a prospective, noncontrolled clinical study. Methods: Sixty patients referred to the emergency department due to unilateral hearing loss (HL) were enrolled. They were asked to press a single uncovered smartphone on their forehead and conduct a Weber test by means of the smartphone’s vibration application. The results were compared to the TFWT. Results: Twenty-six (43%) patients were diagnosed with a SNHL, and 34 (57%) with a CHL. The SPWT was in agreement with the TFWT (at a frequency of 512 Hz) in 55 (92%) patients. The sensitivity and specificity of the TFWT were 84.6 and 94.1%, respectively. The sensitivity and specificity of the SPWT were 76.9 and 97.1%, respectively. Conclusion: SPWT can serve as an auxiliary diagnostic tool in the absence of a 512-Hz tuning fork to assist in the identification of the type of HL and to potentially hasten the diagnosis and provision of treatment when indicated.

Preserved otoacoustic emission in a child with a profound unilateral sensorineural hearing loss

2001 ◽  
Vol 28 ◽  
pp. S117-S120 ◽  
Author(s):  
Ryuichiro Ohwatari ◽  
Satoshi Fukuda ◽  
Eiji Chida ◽  
Michiya Matsumura ◽  
Tsutomu Kuroda ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Otoacoustic Emission ◽  
Sensorineural Hearing

Steroid-dependent sensorineural hearing loss in a patient with Charcot-Marie-Tooth disease showing auditory neuropathy

2015 ◽  
Vol 42 (3) ◽  
pp. 249-253 ◽  
Author(s):  
Yukihide Maeda ◽  
Yuko Kataoka ◽  
Akiko Sugaya ◽  
Shin Kariya ◽  
Katsuhiro Kobayashi ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Auditory Neuropathy ◽  
Sensorineural Hearing ◽  
Charcot Marie Tooth ◽  
Charcot Marie Tooth Disease ◽  
Steroid Dependent ◽  
Tooth Disease

scholarly journals Cortical Neurophysiologic Correlates of Auditory Threshold in Adults and Children With Normal Hearing and Auditory Neuropathy Spectrum Disorder

2020 ◽  
pp. 1-15
Author(s):  
Garrett Cardon ◽  
Anu Sharma
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Normal Hearing ◽  
Auditory Neuropathy ◽  
Auditory Threshold ◽  
Sensorineural Hearing ◽  
Spectrum Disorder ◽  
Threshold Estimation ◽  
Auditory Thresholds ◽  
Auditory Neuropathy Spectrum Disorder

Purpose Auditory threshold estimation using the auditory brainstem response or auditory steady state response is limited in some populations (e.g., individuals with auditory neuropathy spectrum disorder [ANSD] or those who have difficulty remaining still during testing and cannot tolerate general anesthetic). However, cortical auditory evoked potentials (CAEPs) can be recorded in many such patients and have been employed in threshold approximation. Thus, we studied CAEP estimates of auditory thresholds in participants with normal hearing, sensorineural hearing loss, and ANSD. Method We recorded CAEPs at varying intensity levels to speech (i.e., /ba/) and tones (i.e., 1 kHz) to estimate auditory thresholds in normal-hearing adults ( n = 10) and children ( n = 10) and case studies of children with sensorineural hearing loss and ANSD. Results Results showed a pattern of CAEP amplitude decrease and latency increase as stimulus intensities declined until waveform components disappeared near auditory threshold levels. Overall, CAEP thresholds were within 10 dB HL of behavioral thresholds for both stimuli. Conclusions The above findings suggest that CAEPs may be clinically useful in estimating auditory threshold in populations for whom such a method does not currently exist. Physiologic threshold estimation in difficult-to-test clinical populations could lead to earlier intervention and improved outcomes.

scholarly journals Peran Ginkgo biloba terhadap pencegahan gangguan dengar sensorineural pada terapi sisplatin penderita tumor ganas

2015 ◽  
Vol 44 (2) ◽  
pp. 96 ◽  
Author(s):  
Raden Mohamad Krisna Barata ◽  
Muhammad Thaufiq Siddiq Boesoirie ◽  
Ratna Anggraeni Soepardi Poerwana
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Ginkgo Biloba ◽  
Malignant Tumors ◽  
Otoacoustic Emission ◽  
Ginkgo Biloba Extract ◽  
Sensorineural Hearing ◽  
Egb 761 ◽  
Distortion Product Otoacoustic Emission ◽  
Distortion Product

Latar belakang: Kemoterapi sisplatin adalah terapi yang sering diberikan untuk penderita tumor ganas yang mempunyai efek samping ototoksik dengan terbentuknya radikal bebas yang enyebabkan kematian sel rambut luar koklea sehingga terjadi gangguan dengar. Ginkgo biloba adalah antioksidan yang terbukti memiliki efek otoprotektif terhadap ototoksisitas akibat sisplatin dengan menghambat pembentukan radikal bebas. Tujuan: Mengetahui peran Ginkgo biloba terhadap pencegahan gangguan dengar sensorineural pada penderita tumor ganas dengan sisplatin. Metode: Penelitian ini merupakan penelitian uji klinis acak dengan sampel adalah semua penderita tumor ganas yang mendapat kemoterapi sisplatin di Rumah Sakit Hasan Sadikin pada bulan Oktober 2013 sampai Januari 2014. Sampel dibagi dua, kelompok perlakuan menjalani pengobatan kemoterapi sisplatin dengan tambahan ekstrak Ginkgo biloba (Egb 761) peroral 80 mg perhari sejak 1 hari sebelum kemoterapi selama 30 hari. Kelompok kontrol menjalani pengobatan kemoterapi sisplatin saja. Pemeriksaan fungsi pendengaran dilakukan dengan timpanometri, audiometri, dan Distortion Product Otoacoustic Emission (DPOAE) sebelum dan setelah kemoterapi sisplatin siklus pertama dan kedua. Hasil: Didapatkan total 40 data dari 20 pasien yang dibagi dalam dua kelompok. Kejadian gangguan dengar sensorineural setelah siklus pertama dengan pemeriksaan DPOAE didapatkan perbedaan yang bermakna (p=0,027). Kesimpulan: Pemberian terapi ekstrak Ginkgo biloba 80 mg peroral dapat mencegah gangguan dengar sensorineural akibat kemoterapi sisplatin pada penderita tumor ganas. Kata kunci: Sisplatin, Ginkgo biloba, ototoksik, gangguan dengar sensorineural, tumor ganas.ABSTRACTBackground: Chemotherapy with cisplatin is a treatment which often given to patients with malignant tumors with side effects of ototoxicity due to the formation of free radicals that caused cochlea outer hair cells death, causing hearing impairment. Ginkgo biloba is an antioxidant with otoprotective effect to cisplatin induced ototoxicity by inhibiting the formation of free radicals. Purpose:To find out the role of Ginkgo biloba against sensorineural hearing loss in patients with malignant tumors treated with cisplatin. Methods: This is a quasiexperimental clinical trial. The subject were all patients with malignant tumors who received cisplatin chemotherapy in Hasan Sadikin Hospital from October 2013 until January 2014. Sample was divided into 2 groups, the first group (treatment) are those who undergoing cisplatin chemotherapy treatment with additional Ginkgo biloba extract (EGb 761) 80 mg per day orally, started from 1 day prior chemotherapy for 30 days. The second group (control) is those who underwnet only cisplatin chemotherapy. Auditory function were assesed by tympanometry, audiometry and Distortion Product Otoacoustic Emission (DPOAE) examination before and after the first and second cycles cisplatin chemotherapy. Result: The data from right and left ear were analyzed separately, giving total 40 data from 20 patients divided in 2 groups. The incidence of sensorineural hearing loss after first cycle of chemotherapy with the DPOAE results showed significant differencess (p=0,027). Conclusion: Ginkgo biloba extract 80 mg perday orally could prevent cisplatin-induced ototoxicity in patients with malignancy. Keywords: Cisplatin, Ginkgo biloba, ototoxic, sensorineural hearing loss, malignant tumors.

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