scholarly journals Dermatological life quality index in psoriasis

2019 ◽  
Vol 5 (4) ◽  
pp. 812
Author(s):  
N. R. Vignesh ◽  
Jayakar Thomas
Keyword(s):  
Quality Of Life ◽  
Quality Index ◽  
Tertiary Care ◽  
Life Quality ◽  
Inflammatory Disorder ◽  
Scalp Psoriasis ◽  
Patient Reported ◽  
Significant Impairment ◽  
Life Quality Index

<p class="abstract"><strong>Background:</strong> Psoriasis is an immune mediated chronic inflammatory disorder characterized by chronicity of the condition and periods of relapses and remissions. Dermatological life quality index (DLQI) is a widely used measure to determine the patient reported outcome in psoriasis. This study was conducted to evaluate the quality of life in psoriasis patients depending upon their age, sex, type of the disease, duration of the disease and with treatment.</p><p class="abstract"><strong>Methods:</strong> This is a cross sectional study performed in a tertiary care center in Chennai. The study was performed in 100 patients with a prepared DLQI questionnaire. The patients were asked to fill in the questionnaire and the results were graded from mild to very severe.<strong></strong></p><p class="abstract"><strong>Results:</strong> In this study, males outnumbered women in the ratio of 1.2:1. Patients in the age group 41-60 years formed the majority in this study. Itching and soreness of the lesions worsened the DLQI in majority of the patients. Quality of life of patients with psoriasis vulgaris was much affected when compared with other types of psoriasis like erythrodermic and scalp psoriasis. Also, married patients with psoriasis had significant impairment in their quality of life compared to unmarried patients.</p><p class="abstract"><strong>Conclusions:</strong> The findings of this study showed that psoriasis has a significant impairment in the quality of life and hence DLQI should be assessed at the first visit and also after treatment to improve the compliance of the patients towards the doctor as well as to the treatment.</p>

scholarly journals Dermatology life quality index in patients of acne vulgaris presenting to a tertiary care hospital: an observational study

2021 ◽  
Vol 7 (5) ◽  
pp. 692
Author(s):  
Darshana R. Kundale ◽  
Anil P. Gosavi ◽  
Ravindranath B. Chavan ◽  
Neelamkumari Bhatt
Keyword(s):  
Quality Of Life ◽  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Acne Vulgaris ◽  
Tertiary Care ◽  
Life Quality ◽  
Care Hospital ◽  
Age Group ◽  
Life Quality Index

<p class="abstract"><strong>Background: </strong>Acne vulgaris is a common, chronic disorder resulting from the inflammation of pilosebaceous unit, present with clinically various forms. It is usually prevalent in adolescent may persist in adulthood. This study was conducted to evaluate the quality of life (QoL) in patients suffering from acne vulgaris.</p><p class="abstract"><strong>Methods:</strong> Hospital based cross sectional study was conducted in 60 patients. Dermatology life quality index (DLQI) questionnaire was used to observe the effect of acne among patients.</p><p class="abstract"><strong>Results: </strong>Total numbers of patients enrolled were 60 (43 females,17 males). The mean age was 24.85±5.63 years. Maximum patients were of the age group 26-30 years (22 patients; 36%) and least were of 31-36 age group. Out of 60 patients, 29 patients had grade II acne followed by 20 with grade I acne, grade III acne was present in 11 patients. Most of the patients 31 (52%) were having “moderate impact” on quality of life followed by 23 (38%) with “small impact” on QOL. There was a significant positive correlation between grade of acne and DLQI (Pearson correlation=0.753, p=0.00).</p><p class="abstract"><strong>Conclusions: </strong>Our study showed significant impairment of QoL in acne patients. DLQI increases with increase in severity of acne. Treatment of acne should not be guided only by the clinical grade of acne, but take into consideration the psychosocial impact the condition has on the patient. Adequate counselling along with early treatment of acne vulgaris is essential in order to reduce the disease related psychosocial sequelae and increase treatment efficacy.</p>

scholarly journals Translating the Science of Quality of Life into Practice: What Do Dermatology Life Quality Index Scores Mean?

2005 ◽  
Vol 125 (4) ◽  
pp. 659-664 ◽  
Author(s):  
Yan Hongbo ◽  
Charles L. Thomas ◽  
Michael A. Harrison ◽  
M. Sam Salek ◽  
Andrew Y. Finlay
Keyword(s):  
Quality Of Life ◽  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Life Quality ◽  
Life Quality Index

scholarly journals Assessment of the quality of life of pediatric patients at a center of excellence in dermatology in southern Brazil

2012 ◽  
Vol 87 (5) ◽  
pp. 697-702 ◽  
Author(s):  
Magda Blessmann Weber ◽  
Daniel Lorenzini ◽  
Clarissa Prieto Herman Reinehr ◽  
Bárbara Lovato
Keyword(s):  
Quality Of Life ◽  
Skin Disease ◽  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Pediatric Patients ◽  
Skin Diseases ◽  
Life Quality ◽  
Chronically Ill ◽  
Life Quality Index

BACKGROUND: Skin diseases cause negative impact on the emotional state, social relationships and daily activities, due to the stigma caused by the appearance of the lesions. OBJECTIVE: This study aimed to assess the quality of life of pediatric patients with skin diseases attending a dermatology service, compare the scores obtained among the dermatoses found in the sample and associate them to the variables, in addition to observing how the skin disease specifically affects quality of life. METHODS: Cross-sectional study, with patients between 5 and 16 years attending the Dermatology Service of the University of Health Sciences of Porto Alegre, Brazil, between July 2010 and February 2011. The data collection instruments were the Children's Dermatology Life Quality Index questionnaire and the AUEQI questionnaire. RESULTS: A total of 161 patients were interviewed, with mean age of 9,66 years. The main dermatoses were atopic dermatitis (29.8%), warts (13%) and molluscum contagiosum (7.5%). Chronic diseases (73.9%) were the most prevalent. The overall mean Children's Dermatology Life Quality Index score was 5.01 for chronic dermatoses and 2.07 for acute illnesses, indicating a compromised quality of life among chronically ill patients. The comparison between the scores obtained with the AUEQI scale and the Children's Dermatology Life Quality Index scores indicates that the overall quality of life is less affected than the specific quality of life related to the dermatosis. CONCLUSIONS: The data presented reinforce how important it is that the patients, their families and caregivers understand the symptoms, triggers and treatment of the skin disease in question. This information facilitates adherence to the treatment and justifies the conduct adopted by the dermatologist.

Loss of Work Productivity and Quality of Life in Patients With Autoimmune Bullous Dermatoses

2015 ◽  
Vol 19 (6) ◽  
pp. 546-554 ◽  
Author(s):  
K. Heelan ◽  
S. L. Hitzig ◽  
S. Knowles ◽  
A. M. Drucker ◽  
N. Mittmann ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Life Quality ◽  
Work Productivity ◽  
Activity Impairment ◽  
Work Impairment ◽  
Life Quality Index ◽  
The Impact

Background: Little is known about quality of life and work productivity in autoimmune bullous dermatoses (AIBDs). Objective: To determine the impact of AIBDs on quality of life and work productivity. Methods: An observational cross-sectional study took place between February and May 2013 at an AIBD tertiary referral centre. Ninety-four patients were included. All participants completed the Dermatology Life Quality Index and the Work Productivity and Activity Impairment–Specific Health Problem questionnaires. Results: Responders to treatment had less impairment ( P < .001) than nonresponders. Patients with severe AIBD had significantly more impairment that those with mild ( P < .001) and moderate ( P = .002) AIBD. Greater impairment was associated with higher percentage of work missed. Those with a higher Dermatology Life Quality Index score had greater work impairment and overall activity impairment ( P = .041, P = .024). Nonresponders had increased impairment while working ( P < .001), overall work impairment ( P < .001), and activity impairment ( P < .001). Severely affected patients had worse impairment in all Work Productivity and Activity Impairment Questionnaire domains. Conclusions: AIBD has the potential to be a large burden on ability to work and quality of life. Larger studies are needed to clarify how these domains change over time and whether or not they improve with treatment.

Skin Cancer and Quality of Life: Assessment With the Dermatology Life Quality Index

2004 ◽  
Vol 30 (4) ◽  
pp. 525-529 ◽  
Author(s):  
John S. Rhee ◽  
B. Alex Matthews ◽  
Marcy Neuburg ◽  
Timothy L. Smith ◽  
Mary Burzynski ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Skin Cancer ◽  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Life Quality ◽  
Life Assessment ◽  
Quality Of Life Assessment ◽  
Life Quality Index

scholarly journals A study on the dermatology life quality index in patients with acne vulgaris

2019 ◽  
Vol 5 (4) ◽  
pp. 774
Author(s):  
Sangaiah Sivaramakrishnan ◽  
Thomas Jayakar
Keyword(s):  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Acne Vulgaris ◽  
Tertiary Care ◽  
Life Quality ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Significant Impairment ◽  
Life Quality Index

<p class="abstract"><strong>Background:</strong> Acne vulgaris is a common, chronic disorder, involving inflammation of the pilosebaceous units that can be varied in presentation and difficult to treat. Most adolescents experience some acne; however, it may linger into adulthood. This study was done<strong> </strong>to evaluate the dermatology life quality index in patients with acne vulgaris.</p><p class="abstract"><strong>Methods:</strong> A cross sectional study was done with pretested Dermatology life quality index (DLQI) questionnaire on 100 acne patients 15 years and above, in a tertiary care hospital. Interpretation of score and impact on quality of life (QoL) was done and graded as no effect, small effect, moderate effect, and very large effect.<strong></strong></p><p class="abstract"><strong>Results:</strong> In our study, females outnumbered males (M: F ratio=1: 1.22). The age group most affected was within 15 and 20 years of age. The mean DLQI score was 5.59±4.07. Most of them had a ‘small impact’ on the QoL. QoL was worse in females. The most common grade of acne overall was grade 2 acne. Grade 3 acne was more common in men. Most of the patients (84%) experienced some degree of embarrassment or increased self-consciousness due to their acne.</p><p class="abstract"><strong>Conclusions:</strong> Our study showed significant impairment of QoL in acne patients. Treatment of acne should not be guided only by the clinical grade of acne, but take into consideration the psychosocial impact the condition has on the patient. Adequate counselling along with early treatment of acne vulgaris is essential in order to reduce the disease-related psychosocial sequelae and increase treatment efficacy.</p>

scholarly journals Specificity of hand-foot skin reaction induced by multikinase inhibitors: clinical, histological and ultrasound characteristics

2020 ◽  
Vol 10 (2) ◽  
pp. 30-37
Author(s):  
E. A. Shatokhina ◽  
S. B. Potkin ◽  
P. G. Malkov ◽  
L. S. Kruglova ◽  
A. S. Polonskaya
Keyword(s):  
Quality Of Life ◽  
Skin Reaction ◽  
Dermatology Life Quality Index ◽  
Quality Index ◽  
Life Quality ◽  
Reticular Dermis ◽  
Multikinase Inhibitors ◽  
Hand Foot Skin Reaction ◽  
Life Quality Index

Background. Multikinase inhibitors of angiogenesis are currently the most effective group of drugs in target therapy for cancer. They are associated with a high prevalence of a specific cutaneous adverse reaction, which manifests as a hand-foot skin reaction (HFSR). This side effect is quite prominent in the majority of patients, usually graded as II–III degree, which leads to the dose reduction and even discontinuation of the drug. The study objective is to evaluate clinical, histological and ultrasound characteristics of a HFSR associated with MKI treatment, and to assess the influence of a HFSR on patient’s quality of life. Materials and methods. The study included 46 patients with HFSR, who were previously treated with sorafenib or lenvatinib. Clinical characteristics of HFSR, including severity grading, were evaluated. We also performed ultrasound and histological examinations and assess the Dermatology Life Quality Index. Results. Grade III HFSR was in 5 (10.86 %) patients, grade II – in 25 (54.35 %), and grade I – in 16 (34.79 %). Dermatology Life Quality Index depended on the HFSR severity, with the mean value 24.5 ± 2.4. Pathomorphological examination revealed irregular epidermal proliferation with hypertrophic psoriasiform acanthosis, minimal keratinocyte vacuolization, few apoptotic figures, dyskeratosis, hyperkeratosis and microvessel dilation in the papillary dermis. Ultrasound examination showed increased vascularization in papillary and reticular dermis in affected skin areas, which was more prominent in patients with severe degrees of HFSR. The pronounced enhancement of vascularization was detected in fragmented hypoechogenic sites along the border of papillary and reticular dermis and in similar sites along the border of dermis and hypodermis. Conclusion. The use of multikinase inhibitors leads to pronounced changes not only in the surface layers of the skin, but also in the dermis and subcutaneous fat, which significantly worsens the quality of life of patients. This indicates the need to search for pathogenetically based methods of treatment of HFSR and create practical guidelines for supportive treatment of patients with HFSR taking multikinase inhibitors.

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