scholarly journals Granulomatous Slack Skin with Hypercalcemia Indolently Mimicking Sarcoidosis

2021 ◽  
Vol 8 (1) ◽  
pp. 116
Author(s):  
Sarah Colando ◽  
Jennifer Seyffert ◽  
Daniel Rivlin
Keyword(s):  
T Cell ◽  
Rare Variant ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Elastic Fibers ◽  
Cutaneous T Cell Lymphoma ◽  
Unique Case ◽  
History Of ◽  
Previously Treated

<p class="abstract">Granulomatous slack skin is a rare variant of cutaneous T-cell lymphoma characterized by lax skin and granulomatous infiltrate with loss of elastic fibers on histology. We report a unique case of a female presenting with CD30-granulomatous slack skin complicated by hypercalcemia, initially diagnosed, and managed as sarcoidosis. Interestingly, she had a history of previously treated CD30+ cutaneous T-cell lymphoma. Granulomatous slack skin can frequently mimic other benign and malignant cutaneous diseases, prompting the need for clinical vigilance from dermatologists.</p>

A rare variant of cutaneous T-cell lymphoma

2004 ◽  
Vol 50 (3) ◽  
pp. P114
Author(s):  
Helen Radoszycki ◽  
Alyson Penstein
Keyword(s):  
T Cell ◽  
Rare Variant ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma

scholarly journals Primary Cutaneous CD30-Positive Large T-Cell Lymphoma in an 80-Year-Old Man: A Case Report

2011 ◽  
Vol 2011 ◽  
pp. 1-3 ◽  
Author(s):  
Rehan Hussain ◽  
Amir Bajoghli
Keyword(s):  
T Cell ◽  
Cell Lymphoma ◽  
Large Cell ◽  
T Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma ◽  
Left Forearm ◽  
Favorable Prognosis ◽  
History Of ◽  
Indolent Disease ◽  
Rule Out

Primary cutaneous CD30-positive large cell lymphoma (CD30+ PCLCL) is a rare subtype of cutaneous T-cell lymphoma (CTCL) that can present in a variety of ways. We report a patient with a three-month history of an enlarging, exophytic mass with two smaller satellite lesions on the left forearm. Biopsy of the skin stained positive for CD30, and, after thorough systemic evaluation, a diagnosis of CD30+ PCLCL was made. When PCLCL is suspected, it is important to perform immunohistological studies for CD30 types and conduct a thorough workup to rule out systemic LCL. These measures will reduce the use of unnecessarily aggressive chemotherapy regimens for CD30+ PCLCL, an indolent disease with a favorable prognosis.

scholarly journals Matrix Metalloproteinase-2 Promoter Genotype as a Marker of Cutaneous T-Cell Lymphoma Early Stage

2010 ◽  
Vol 2010 ◽  
pp. 1-5 ◽  
Author(s):  
Anna Vasku ◽  
Julie Bienertova Vasku ◽  
Miroslav Nečas ◽  
Vladimir Vasku
Keyword(s):  
T Cell ◽  
Skin Diseases ◽  
Cell Lymphoma ◽  
Early Stage ◽  
Clinical Diagnostics ◽  
T Cell Lymphoma ◽  
Matrix Metalloproteinase 2 ◽  
Potential Candidate ◽  
Cutaneous T Cell Lymphoma ◽  
History Of

The aim of the study was to investigate the DNA polymorphic genotype in MMP-2 promoter gene as a potential candidate region for the development of the cutaneous T-cell lymphoma (CTCL) and/or its progression. A total of 89 Czech patients with CTCL (including 23 patients with large plaque parapsoriasis) were compared to 198 controls of similar age and sex distribution, without personal or family history of chronic skin diseases and without personal history of malignancy. The three selected polymorphisms in the promoter of MMP-2 gene (−1575G/A,−1306C/T, and−790T/G) were determined using the PCR-based methodology with RFLP. In our cohort, the associatedGGCCTTMMP-2 promoter genotype was highly significantly more frequent in CTCL-Ia stage patients compared to patients with parapsoriasis, the tests having high sensitivity and specificity (78%, 83%, resp.). To conclude, use of associated MMP-2 promoter genotype as a DNA marker might make it possible to distinguish between the patients with parapsoriasis and those with CTCL stage Ia, which could substantially improve possibilities of clinical diagnostics, therapy design, and prognosis of this serious condition in the early stages.

Woringer-Kolopp Disease of the Foot: A Case Report

2020 ◽  
Vol 110 (6) ◽  
Author(s):  
James J. LaPolla ◽  
Lawrence A. DiDomenico ◽  
Robert T. Brodell ◽  
Michael L. Casteel
Keyword(s):  
Case Report ◽  
T Cell ◽  
Mycosis Fungoides ◽  
Rare Variant ◽  
Cell Lymphoma ◽  
Treatment Options ◽  
T Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma ◽  
Review Of The Literature ◽  
Intralesional Steroids

Woringer-Kolopp disease is a rare variant of mycosis fungoides, a type of cutaneous T-cell lymphoma. Described is a case of a small annular plaque on the foot diagnosed histologically as Woringer-Kolopp disease and treated successfully with topical and intralesional steroids. In addition, a brief review of the literature and treatment options is provided.

Cutaneous T‐cell lymphoma mimicking palmoplantar pustular psoriasis: A rare variant

2021 ◽  
Author(s):  
Emma Hignett ◽  
Lucia Seminario‐Vidal ◽  
Kenneth Shulman ◽  
Naveed Sami
Keyword(s):  
T Cell ◽  
Rare Variant ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Pustular Psoriasis ◽  
Cutaneous T Cell Lymphoma

scholarly journals Mogamulizumab versus vorinostat in previously treated cutaneous T-cell lymphoma (MAVORIC): an international, open-label, randomised, controlled phase 3 trial

2018 ◽  
Vol 19 (9) ◽  
pp. 1192-1204 ◽  
Author(s):  
Youn H Kim ◽  
Martine Bagot ◽  
Lauren Pinter-Brown ◽  
Alain H Rook ◽  
Pierluigi Porcu ◽  
...  
Keyword(s):  
T Cell ◽  
Cell Lymphoma ◽  
T Cell Lymphoma ◽  
Cutaneous T Cell Lymphoma ◽  
Open Label ◽  
Phase 3 ◽  
Previously Treated ◽  
Randomised Controlled
Sign in / Sign up

Export Citation Format

Share Document