Bacteriological profile and antibiotic sensitivity in Chronic Suppurative Otitis Media

2020 ◽  
pp. 1-4
Author(s):  
Ajit Damle

Introduction: Chronic suppurative otitis media (CSOM) is a destructive and persistent disease with irreversible sequel and can proceed to serious intra and / or extra cranial complications. Causative agents of infection include bacteria, fungi and viruses with bacteria being the commonest cause. Hence bacteriological studies of CSOM are important for determining effective antibiotic choice and surveillance of bacterial patterns and their relative sensitivities. Materials and Methods:Total 157 patients having CSOM were included in the study. Ear discharge was processed with standard Microbiological procedures. Results: On aerobic culture Staphylococcus aureus 58 (36.96%) was the most common isolate followed by Pseudomonas aeruginosa 35 (21.21%). Fungal culture yielded 19 (11.2%) isolates. Conclusion: Evaluation of microbiological pattern and antibiotic sensitivity of isolates is necessary to decrease the potential risk of complications of CSOM by early institution of appropriate treatment.


Author(s):  
Kiran J. Shinde ◽  
Netra A. Pathak ◽  
Namrata J. Katake

<p class="abstract"><strong>Background: </strong>Chronic suppurative otitis media is a long-standing infection of the middle ear cleft which is characterized by recurrent and persistent ear discharge and persistent non healing perforation of tympanic membrane. It can lead to severe complications if not treated appropriately. Due to emerging antibiotic resistance, it is necessary to understand the antimicrobial pattern and their sensitivity to antibiotics which will help clinicians to select antibiotic which is sensitive to their corresponding microorganism. The aim of the study is to isolate the prevalent microorganism and study their antibiotic sensitivity pattern in patients of chronic suppurative otitis media (CSOM).</p><p class="abstract"> <strong>Methods:</strong> Total 100 patients were examined, ear swab were collected by sterile ear swab and sent for microscopy and culture sensitivity examination to microbiology department. Results were documented and analyzed.</p><p class="abstract"><strong>Results: </strong>Pseudomonas aeruginosa was the most common isolate (41%) followed by Staphylococci (28.2%). Gram negative cocci showed high degree of sensitivity to Cotrimoxazole (100%), Amikacin (79%) and Piperacillin - tazobactum (75%). Gram positive cocci showed high degree of sensitivity to Linezolid.</p><p class="abstract"><strong>Conclusions: </strong>Study of bacteriological profile and their sensitivity pattern helps in empirical therapy and reduces the risk of complications.</p>


Author(s):  
Rashmi Ramashesh ◽  
Samira Abdul Wajid ◽  
Smitha Chandra

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is an ever growing concern of preventable hearing loss and is a major health concern especially in tropical countries. Lack of cleanliness, overcrowding, poverty, malnutrition and medical ignorance are few of the contributing factors. The microbiological flora is constantly changing due to indiscriminate use of antibiotics with rapid change in the antibiotic sensitivity patterns. Hence, this study was undertaken to determine the epidemiological profile, bacteriological profile and the antibiotic sensitivity pattern which would help in establishing a protocol in management of CSOM patients in the hospital.</p><p class="abstract"><strong>Methods:</strong> A total of 100 patients of CSOM attending the ENT Outpatient Department of The Oxford medical College, Hospital and Research Centre were included in the study. The samples were immediately sent to the Microbiology laboratory for further processing according to standard procedure.  </p><p class="abstract"><strong>Results:</strong> Out of 100 cases, 74 were active mucosal type and 26 were active squamous, with Pseudomonas species (33.6%) being the predominant organism. <em>Staphylococcus aureus</em> was the next common organism with MSSA (16.3%) and MRSA (12.5%), CONS were 6.7%. Among the 28 gram-negative bacilli, <em>Klebsiella pneumoniae</em> (7.7%), was followed by <em>Escherichia coli</em> (5.7%), and <em>Proteus mirabilis</em> (4.8%).</p><p class="abstract"><strong>Conclusions:</strong> Pseudomonas species and <em>Staphylococcus aureus</em> are the commonest organisms of CSOM. Ciprofloxacin can be used as a topical agent for treating gram-negative bacilli. Among systemic antibiotics- Linezolid, Amikacin and Imepenam remains the drug of choice.</p><p><br /><br /></p>


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