Dexmedetomidine and Buprenorphine as Adjuvant to Hyperbaric Bupivacaine for Spinal Subarachnoid Block - A Comparative Study

2017 ◽  
Author(s):  
P. Shubha ◽  
Karl Sa Ribeiro
Keyword(s):  
Comparative Study ◽  
Hyperbaric Bupivacaine ◽  
Subarachnoid Block

scholarly journals Comparative Study of Hyperbaric Bupivacaine and Isobaric Ropivacaine for Lower Limb Surgery under Spinal Anesthesia

2019 ◽  
Vol 2 (2) ◽  
pp. 22-27
Author(s):  
Gunjan Regmi ◽  
Rejina Shahi ◽  
Kanak Khanal ◽  
Kumud Pyakurel ◽  
Chetan Bohora ◽  
...  
Keyword(s):  
Heart Rate ◽  
Comparative Study ◽  
Spinal Anesthesia ◽  
Lower Limb ◽  
Motor Block ◽  
Hyperbaric Bupivacaine ◽  
Subarachnoid Block ◽  
Arterial Blood ◽  
Group I ◽  
Lower Limb Surgery

Introduction: Subarachnoid block is commonly employed technique for lower abdominal and lower limb procedures. Bupivacaine and ropivacaine are commonly used local anesthetics for subarachnoid block. The aim of this study is to compare the efficacy and safety of isobaric Ropivacaine over hyperbaric Bupivacaine. Methods: This was a prospective comparative study for a duration of six months. 60 ASA grade I-II adult patients between 16-60 years undergoing lower limb surgery under spinal anesthesia were randomized into two groups. Group I including patients who received 15 mg of hyperbaric bupivacaine 0.5% and group II including patients who received 22.5 mg of isobaric ropivacaine 0.75%. The onset and duration of sensory and motor block and hemodynamics including heart rate (HR), non invasive mean arterial blood pressure (MAP) and respiratory depression were recorded. Data were entered in Microsoft excel and statistical analysis was done by chi square test and T test using SPSS (version 23.0). Results: Both the groups were demographically statistically insignificant. Successful block was attained in all patients in both groups. The sensory onset and motor onset were significantly delayed in the Ropivacaine Group compared to the Bupivacaine Group P<0.001. There was no significant difference in the hemodynamics (heart rate and mean arterial pressure ). Conclusions: Though isobaric ropivacaine provided lesser degree of sensory and motor block with delayed onset compared to hyperbaric bupivacaine, it can effectively and safely used in subarachnoid block in lower limb surgeries without any major hemodynamic changes and adverse effects.

scholarly journals Clinical benefits of preemptive oral clonidine versus oral tramadol for abdominal hysterectomy conducted under subarachnoid block with 0.5% hyperbaric bupivacaine: a comparative evaluation

2017 ◽  
Vol 5 (7) ◽  
pp. 3129
Author(s):  
Kumkum Gupta ◽  
Swati Sharma ◽  
Prashant K. Gupta ◽  
Guljeet Kaur ◽  
Vasundra Tyagi ◽  
...  
Keyword(s):  
Muscle Relaxation ◽  
Abdominal Hysterectomy ◽  
Hyperbaric Bupivacaine ◽  
Subarachnoid Block ◽  
Oral Clonidine ◽  
Significant Difference ◽  
Clinical Benefits ◽  
Intraoperative Period ◽  
American Society ◽  
To Receive

Background: Neuraxial techniques possess many benefits for elective abdominal hysterectomy due to profound surgical anesthesia and muscle relaxation. The present study was aimed to compare the clinical benefits of pre-emptive oral clonidine with oral tramadol for abdominal hysterectomy conducted under subarachnoid block with 0.5% hyperbaric bupivacaine.Methods: Sixty adult female patients of American Society of Anaesthesiologists (ASA) physical status I and II, aged 42 to 65 years, were randomized into two groups of 30 patients each to receive either oral clonidine, 100 µg (Group C) or oral tramadol 50 mg tramadol (Group T), 90 min before initiation of subarachnoid block with 3.5 mL of 0.5% hyperbaric bupivacaine. Intraoperative hemodynamic changes, duration of analgesia and incidence of shivering were recorded as primary end points. Drug related effects of pruritus, sedation, nausea, vomiting, and respiratory depression were recorded as secondary outcomes.Results: The onset of sensory and motor block was comparable between the groups but the time to two dermatome regression were prolonged in patients of Group C with statistical significant difference (p=0.05). Duration of analgesia was also enhanced in patients of Group C (268.27±12.18 min versus 223.15±14.31 min in Group T) with statistically highly significant difference (p=0.000). The incidence of shivering was lower in the patients of clonidine group. The heart rate was lower in patients of clonidine throughout intraoperative period and no incidence of bradycardia, hypotension or sedation occurred in any patient.Conclusions: Both drugs showed clinical benefits as pre-emptive oral medication for abdominal hysterectomy conducted under subarachnoid block but oral clonidine (100 µg) proved to be more beneficial.

scholarly journals Combined spinal epidural anaesthesia versus epidural anaesthesia: a comparative study

2020 ◽  
Vol 10 (2) ◽  
pp. 36-39
Author(s):  
Pramesh Sunder Shrestha ◽  
Ninadini Shrestha ◽  
Anil Shrestha ◽  
Roshana Amatya ◽  
Bigen Man Shakya ◽  
...  
Keyword(s):  
Comparative Study ◽  
Epidural Anaesthesia ◽  
Epidural Block ◽  
Spinal Block ◽  
Epidural Group ◽  
Hyperbaric Bupivacaine ◽  
Chi Square ◽  
Cross Sectional ◽  
Group B ◽  
Spinal Epidural

Background: Regional anaesthesia are widely utilized in surgical gynaecology practice. The Com­bined Spinal Epidural Anaesthesia (CSEA) technique and Continuous epidural anaesthesia both have been extensively used in elective gynaecological surgeries. This prospective cross-sectional comparative study was designed to compare the quality of anaesthesia between CSEA and Epi­dural anaesthesia. Methods: Sixty-four patients between age group 15- 65 years of ASA grade I, II were randomly di­vided into 2 groups. Group A patients received CSEA using “double needle double interspace tech­nique” and were given 2.5 ml of 0.5% hyperbaric bupivacaine for spinal block. Group B patients received epidural block with catheter using 10 ml of 0.5% plain bupivacaine. In all patients, subse­quent dosage of 2 ml per unblocked segment 0.5% plain bupivacaine was administered through the epidural catheter to achieve a block up to T4-5. Mean was calculated using t-test, median with Mann Whitney U test and Chi-square test where appropriate and the Statistical Analysis was done using SPSS program, version 11.0. Results: The surgical anaesthesia and motor blockade occurred significantly early in CSEA group. Duration of analgesia was significantly shorter in CSEA (84.1±40.6 min) as compared to epidural group (138.6±32.9 min). The total amount of bupivacaine required to attain the same target level was two times in epidural group (p<0.05). Haemodynamic changes were comparable in both the groups. No neurological side effects were observed. Conclusions: Sequential CSEA is superior alternative to epidural block, which combines the advan­tages of spinal and epidural while minimizing their drawbacks in elective gynaecological surgeries.

scholarly journals Comparative Study of 0.5% Hyperbaric Bupivacaine and 0.5% Hyperbaric Tetracaine in Spinal Anesthesia

2000 ◽  
Vol 38 (6) ◽  
pp. 1002
Author(s):  
Dong Choon Ha ◽  
Yong Hun Jung ◽  
Young Hi Lee ◽  
Byoung Youn Jeoung
Keyword(s):  
Comparative Study ◽  
Spinal Anesthesia ◽  
Hyperbaric Bupivacaine ◽  
Hyperbaric Tetracaine
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