scholarly journals A Neurocosmological Neurotheology Organized Around Reissner’s Fiber

2018 ◽  
Vol 1 (1) ◽  
pp. 56-65
Author(s):  
Lawrence Wile
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Genetic Analysis ◽  
Central Axis ◽  
Religious Experiences ◽  
Reissner's Fiber ◽  
Scientific Rigor ◽  
New Approach ◽  
Reissner’S Fiber ◽  
The Central Nervous System

Neurotheology is the study of the neurobiological correlates of religious experiences. A key problem for this nascent field is that interpretations of religious experiences range from a regression to the oceanic oneness of the womb to supersensory apprehensions of transcendent realities. Identifying appropriate subjects is therefore problematic. Correlating the complex array of neurobiological data obtained from neuroimaging, genetic analysis and lab tests with such elusive “religious experiences” offers little hope of scientific rigor. This paper proposes a new approach. Mystical traditions have consistently described a “subtle anatomy” organized around a circuit running through the center of the spine that connects the human and the divine. If descriptions of this circuit are based on actual interoceptions, then it corresponds to a little-known, epigenetically suppressed structure that ensheathes the central axis of the central nervous system; Reissner’s fiber (RF). Rather than identifying subjects based on self-reporting and correlating their experiences with an array of neurobiological data, this new approach would regenerate the fiber, measure its activity and explore possible correlations with religious experiences.

scholarly journals The Broken Thread of Asian Culture

2018 ◽  
Vol 3 (2) ◽  
pp. 65
Author(s):  
Lawrence Wile
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Empirical Testing ◽  
Reissner's Fiber ◽  
Reissner’S Fiber ◽  
Justified Belief ◽  
Theory Of Religion ◽  
The Central Nervous System ◽  
Sociobiological Theory ◽  
Anatomical Connection

Sociobiology derives its atheistic stance from the Darwinian framework of purposeless, naturally selections of random variations of matter in motion. However, explanatory gaps in sociobiology’s explanation of religion, from the initial cosmic singularity to free will, invite a Divine foot in the door. By interpreting yogic, Taoist and Kabbalistic descriptions of the anatomical connection between the human and the divine not as primitive, poetic metaphors but as interoceptions of a little-known, enigmatic, epigenetically suppressed, structure running through the central axis of the central nervous system called Reissner’s fiber. I propose a new theistic sociobiological theory of religion. Justified belief in this theory could epigenetically reawaken the suppressed Reissner’s fiber genes and begin the empirical testing of the theory.

scholarly journals Dying to Fall Asleep

2019 ◽  
pp. 724-742
Author(s):  
Jessica Vensel Rundo ◽  
Hillor Mehta ◽  
Reena Mehra
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Genetic Analysis ◽  
Genetic Disease ◽  
Prion Proteins ◽  
Amyloid Plaques ◽  
Definitive Diagnosis ◽  
Common Features ◽  
The Central Nervous System ◽  
Autonomic Hyperactivity

Fatal familial insomnia (FFI) is a rare autosomal dominant genetic disease characterized by progressive insomnia, autonomic hyperactivity, memory deficits, hallucinations, and myoclonus. Unlike its name, insomnia is not the most common initial presentation in patients with FFI. More common features like autonomic hyperactivity (hypertension and tachycardia) are often missed, delaying the diagnosis of FFI. Genetic analysis of FFI shows a D178N-129M mutation that results in generation of insoluble proteins (prion proteins) that aggregate to form amyloid plaques, leading to deterioration of the central nervous system, particularly in the hypothalamus. This case illustrates the difficulty in determining a definitive diagnosis in patients with FFI. Unfortunately, no treatment or cure is available for FFI. The disease is fatal in all the patients.

scholarly journals Burkitt Lymphoma of Central Nervous System in an elderly-patient: A new approach with a modified classic regimen

2021 ◽  
pp. 244
Author(s):  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Tumor Response ◽  
Progression Free Survival ◽  
Clinical Prognosis ◽  
Free Survival ◽  
New Approach ◽  
The Central Nervous System ◽  
Unfit Patients ◽  
The One

Burkitt’s lymphoma (BL) is one of the high-grade lymphomas, characterized by a rapid growth. They are usually treated with intensive chemotherapy regimens, being normally chemo-sensitive, but at the expense of high toxicity secondary to treatment. Additionally, the compromise of the central nervous system (CNS) implies a major risk as well as greater toxicity, taking into account a worse clinical prognosis with a requirement of more intensive schemes to achieve control of the disease. This implies doubts in the management of older patients with BL with CNS compromise, in whom toxicity is a limitation to these therapies, and there are no other alternatives that offer better benefit in terms of less frequent or severe adverse events, with similar outcomes in terms of progression-free survival (PFS) or overall survival (OS). Therefore, clarifying cases such as the one we report below allows us to provide a therapeutic alternative for older or unfit patients, in whom the intention of treatment should be to seek a good tumor response, but without ignoring the potential toxicity of chemotherapy.

scholarly journals Hedonic representations in primary somatosensory cortices; Pain but not pleasure?

2020 ◽  
Author(s):  
James H. Kryklywy ◽  
Mana R. Ehlers ◽  
Andre O. Beukers ◽  
Sarah R. Moore ◽  
Rebecca M. Todd ◽  
...  
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Internal State ◽  
Somatosensory System ◽  
Similarity Analysis ◽  
New Approach ◽  
External Stimulation ◽  
Somatosensory Cortices ◽  
Sensory Cortices ◽  
The Central Nervous System

AbstractIn the somatosensory system, hedonic information is coded by mechanoreceptors at the point of contact. Pleasure and pain signals travel along peripheral nerve pathways distinct from those for discriminative touch. Yet it remains unknown whether the central nervous system represents tactile hedonic information in sensory cortices as another dimension of exteroceptive information, similar to discriminative touch signals, or if tactile hedonic information is instantiated in regions mediating internal interoceptive states. Employing representational similarity analysis with a new approach of pattern component modeling, we decomposed multivoxel patterns to demonstrate that signals of painful but not pleasurable touch are represented in primary somatosensory cortices. By contrast, all hedonic touch representations were identified in regions associated with affect and interoception. This suggests that touch should be divided into external-exteroceptive and internal-interoceptive dimensions, with hedonic touch represented as an internal state, even though evoked by external stimulation.

scholarly journals Determinant genes that effect the central nervous system and their antenatal identification

2020 ◽  
Vol 9 (11) ◽  
pp. 4612
Author(s):  
Christy Vijay ◽  
Preetha Tilak
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Genetic Analysis ◽  
Complex Structure ◽  
Genetic Mutation ◽  
Temporal Region ◽  
Genetic Syndromes ◽  
Mri Findings ◽  
Diagnostic Center ◽  
The Central Nervous System

Background: The central nervous system is an intricate networking of electric signals that intertwines the functioning of all senses of speech, thoughts etc. A genetic mutation in this complex structure is known to cause many neurological diseases.Methods: Records of the genetic analysis reports of patients were studied. Patients with CNS genetic syndromes or tubulinopathies in fetus of the present pregnancy or previous pregnancy who presented themselves only for genetic counseling with the genetic analysis report done at an outside diagnostic center were selected.Results: Ten patients presented with history congenital abnormalities of the structure of the central nervous system in pregnancy. Non-invasive investigations in the first child led to the need for genetic analysis of the present foetus. EEG showing independent S2 foci and left central parietal and right temporal region with bilateral synchronous discharge was noticed. MRI findings such as chronic infarct with encephalomalacia were seen.Conclusions: Our study identified genes responsible for CNS abnormalities in structure and function and the Exom sequence in which they occurred. We were able to observe various types of clinical presentations of the syndromes on MRI/USG.

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