scholarly journals Antibody to Hepatitis B Surface Antigen in Vaccinated Healthcare Workers in a Tertiary Care Centre – A Descriptive Study from South Kerala

2021 ◽  
Vol 8 (20) ◽  
pp. 1554-1558
Author(s):  
Sathya Bhama M.C ◽  
Saritha Narayanan Kutty ◽  
Jyothi Rajahamsan

BACKGROUND Hepatitis B virus (HBV) has long been recognized as a work-related hazard for health-care personnel (HCP). HCPs are all paid and unpaid persons giving health care or working or training in health-care settings, who have reasonably expected risks for exposure to infectious materials. Post-vaccination serological testing is suggested 4 to 8 weeks after completion of the primary course in all health care workers. If the anti - HBs levels are less than 10 mIU / ml 4 - 8 weeks after the third dose of vaccine, the person's serum has to be tested for markers of HBV. The objective of the study was to evaluate the immune response after hepatitis B vaccination in health care workers. METHODS This study was a cross-sectional study that was conducted for a period of one year (January 2016 – December 2016). In this study, blood samples of 211 HCP were collected and sera were tested for quantitative anti - HBs level using anti - HBs EIA kit (Diapro, Italy). RESULTS 75. 83 % of HCP were completely vaccinated and 24.17 % did not complete the three-dose regimen. 91.87 % of completely vaccinated HCP had an anti- HBs titre of more than 10mIU/ml while 80.39 % of incompletely vaccinated HCP had protective antibody levels. 71.42 % of males and 90.35 % of females had protective antibody titre. The housekeeping staff were the most protected (100 %) while doctors were the least protected (54.54 %). Among the different vaccine, compliant subgroups 85.96 % of HCP who were completely vaccinated and had not taken booster dose had protective antibody titre even after five years where as 90.47 % of HCP who were completely vaccinated and had taken a booster dose and had protective antibody titre even after 5 years. It was also noted that 95.23 % of HCP who were vaccinated before the age of 20 had a protective antibody titre while only 70.58 % of those who got vaccinated after the age of forty had a protective antibody titre. CONCLUSIONS The records, if possible retrievable electronic records, should be maintained in health care centers as a reference in case of occupational exposure or for other purposes. KEYWORDS Hepatitis B, Anti HBs, Health Care Personnel

Author(s):  
Vani Srinivas ◽  
Tess Shajan ◽  
Sudheesh Muthuthodiyil Karippankunnath ◽  
Theertha Pradeep Reshmi ◽  
Vidhu Victor ◽  
...  

Background: Hepatitis B is one of the most important blood borne infection, the health care workers may acquire while providing care to the patients. The overall aim of this study was to estimate the Hepatitis B vaccine coverage and its determinants among health care workers.Methods: This cross-sectional study was done in a rural tertiary care hospital in Palakkad district, of Kerala. We particularly looked for self-reported hepatitis B vaccination coverage and its determinants, using self-administered pretested questionnaire in 410 health workers. We calculated the proportions and looked for association between the various independent variables and dependent variables for vaccination coverage.Results: Out of 410 study participants, 119 (29%) of them were males and 291 (71%) of them were females. The mean age of the participant was 31.3 years and the range was between 19 to 70 years. 365 (89%) were vaccinated with atleast one dose of Hepatitis B Vaccine. Of these 306 (74.6%) had received all the 3 doses of vaccine, as per schedule. Gender and years of experience was not associated with the Hepatitis B vaccination status. However, variables like educational status, professional background was associated with hepatitis B vaccine coverage.Conclusions: The coverage of hepatitis B vaccine was high. Among those with incomplete vaccination few of them were waiting for completing the vaccination schedule in near future. Good hospital policies like vaccinating the new medical students and new employees were the main factors responsible for high vaccination coverage among the health care workers in our study.


2021 ◽  
Vol 2 (1) ◽  
pp. 57-62
Author(s):  
A S Obekpa ◽  
A O Malu ◽  
R Bello ◽  
M Duguru

Health care workers are high-risk group for contracting hepatitis B and C virus infections. Hepatitis B and C can be contracted in the hospital setting by needle prick injury, contact with blood (and body fluids) and during invasive medical procedures. This study aims to assess the risk of exposure, the concern or perception of healthcare workers about getting infected (with HBV and/or HCV) from the workplace and the level of HBV vaccination uptake among them. The study was carried out during a capacity building workshop organized for health care workers from all the Local Government Areas in Benue State. A self-administered questionnaire was distributed to 168 participants in attendance, after obtaining verbal consent. One hundred and thirty-eight (138) questionnaires were properly filled and returned, 115 (83.3%) have had needle prick injury, 127 (92%) have had blood spilling on them and 118 (85.5%) have been involved in the management of hepatitis patients. One hundred and nineteen (86.2%) were afraid of contracting hepatitis infection from their place of work, 133 (96.4%) were aware of hepatitis B vaccine for adult, 87 (63%) had received at least one dose of hepatitis B vaccine but only 56 (40.6%) received the complete three doses. Health care workers in Benue State are aware of the risk of contracting viral hepatitis at their workplace and are concerned about this risk. However, the uptake of hepatitis B vaccination among them remains poor.


2013 ◽  
Vol 23 (1) ◽  
pp. 72-77 ◽  
Author(s):  
H.G. Ouédraogo ◽  
S. Kouanda ◽  
S. Tiendrébeogo ◽  
G.A. Konseimbo ◽  
C.E. Yetta ◽  
...  

1988 ◽  
Vol 9 (10) ◽  
pp. 462-464 ◽  
Author(s):  
Michael B. Snyder

The availability of both plasma-derived and recombinant hepatitis B vaccines has given hospitals and other health care institutions the possibility of significantly reducing a major infectious hazard in the workplace. With the increasing use and acceptance of these vaccines, many employees who have a significant blood or body fluid exposure (percutaneous or mucous membrane) have already completed hepatitis B vaccination. Concerns have arisen over the duration of protection of vaccination, as it has been over five years since the introduction of the plasma-derived vaccine.


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