scholarly journals Trichomonas Vaginalis Infection in Men with High-Risk Sexual Behaviors

Author(s):  
Abdolhossein Dalimi ◽  
Samira Payameni

Background: Trichomonas vaginalis is a protozoan pathogen of the human genitourinary tract, which is the cause of trichomoniasis. The disease is one of the most important non-viral sexually transmitted infections in the world. Many studies have been performed on the molecular identification of Trichomonas in men in different parts of the world, but in Iran, such a study has been very limited. We aimed to detect T. vaginalis in urine of men with unusual sexual behavior by wet mount microscopic observation, culturing in TYM-33 and molecular method in Tehran, Iran. Methods: Totally, 47 urine samples were collected from men with high-risk sexual behaviors referred to Health Care Centers in South of Tehran, Iran during 2017-2018. After urine centrifugation and wet mount sediment preparation, the samples were cultured in TYM-33 medium and examined microscopically. Then DNA was extracted from urine sediment samples and finally the 18srRNA gene was amplified by PCR. Results: Thirty-one (65.95%) urine samples were positive for T. vaginalis by PCR. Of these, only 6 (12.76%) were detected positive by wet mount method and 25 (53.19%) by culture and successive passages.  Conclusion: The high prevalence of trichomoniasis among men with high-risk sexual behavior in Tehran indicates a potent health risk condition for families. Of course, this percentage is not the real infection rate in ordinary men in Tehran. This situation could be controlled by promoting concurrent diagnosis and treatment of T. vaginalis infection in men and women, as well as strengthening religious beliefs and health education in the individuals.

Author(s):  
Hyunjean Kim ◽  
Yingxin He ◽  
Ryan Pham ◽  
Gira J. Ravelo ◽  
Patria Rojas ◽  
...  

Latinas are often more affected by HIV due to their socio-economic and demographic profiles and are also less likely to receive proper mental health care. Latina immigrants are often even more vulnerable due to socio-economic and cultural factors that place them at higher risk. The current study seeks to examine the association between depression and risky sexual behaviors among adult Latina immigrants from a farm working community in South Miami-Dade County, (Florida, USA). Cross-sectional secondary data analysis was used for responses from a community-based participatory research (CBPR) study. Out of 234 Latina immigrants, 15% reported being depressed and 80% were reported as having engaged in risky sexual behavior. Although no association was found between depression and high-risk sexual behavior, significant secondary findings present associations between risky sexual behavior and low sexual relationship power, interpersonal violence, and relationship status. Implications for future research on depression and risky sexual behaviors among this population are discussed.


2015 ◽  
Vol 45 (2) ◽  
pp. 459-465 ◽  
Author(s):  
Dennis E. Reidy ◽  
Kathryn A. Brookmeyer ◽  
Brittany Gentile ◽  
Danielle S. Berke ◽  
Amos Zeichner

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S527-S528
Author(s):  
Stephanie Clavijo ◽  
Matthew Herrmann ◽  
Katya Corado

Abstract Background According to the Centers for Disease Control (CDC), PrEP coverage in the United States was approximately 18% in 2018 and 21.9% in California. We predict that PrEP prescription is lower at Harbor-UCLA Medical Center (HUMC) and affiliated clinics within Los Angeles County Department of Health Services. Methods A retrospective chart review of HIV-negative patients with ICD-10 coded diagnoses of sexually transmitted infections (STIs) or high-risk sexual behavior was performed across various medical specialties at HUMC and affiliated clinics in 2018. Documentation of sexual behavior risk reduction counseling, PrEP discussion and prescription was reviewed from electronic medical records for each encounter. Descriptive statistics and analysis were completed in STATA Version 16.1, StataCorp LLC. Results The sample included 250 individual patients, all with indications for PrEP. Of those, 47.2% identified as Latinx and 27.2% Black. Table 1 shows 74% of patients identified as heterosexual whereas 9.2% identified as gay, and 4.4% bisexual. Of the 250 individual patients, 87 (34.8%) returned for a 2nd visit, 35 (14.0%) for a third, and 9 (3.6%) for a 4th visit, for a total of 381 encounters. Of the total encounters, 49.3% had sexual behavior risk reduction counseling, 7.3% had discussions about PrEP with their provider, and only 2.1% were newly prescribed PrEP (Table 2). Of the 2.1% new PrEP prescriptions, 1.8% were prescribed by family medicine providers with no new prescriptions by OB/GYN or acute care providers. Only 25% of new PrEP prescriptions were female patients. A positive test for an STI occurred in 45.1% of total encounters while high risk sexual behavior was identified in 54.9% of encounters (Table 3). Table 1: First Encounter Demographics (N=250 Individual Patients) Table 2: Primary Outcomes by Specialty (N=381 Total Encounters) Table 3: Sexually Transmitted Infections Frequency (N=381 Total Encounters) Conclusion Our findings demonstrate that the percent of individuals newly prescribed PrEP (2.1%) at HUMC and affiliated clinics is less than that reported nationally and in California. This suggests that municipal health systems fall short in PrEP usage, notably for structurally vulnerable populations such as racial minorities as well as heterosexual females. Ending racial/ethnic disparities in HIV and in PrEP coverage not only requires educating specialty providers on PrEP, but also addressing structural racism and identifying structural barriers to care in vulnerable communities. Disclosures All Authors: No reported disclosures


2021 ◽  
Vol 15 (02) ◽  
pp. 297-300
Author(s):  
Vito Fiore ◽  
Andrea De Vito ◽  
Nicholas Geremia ◽  
Petrana Martineková ◽  
Elija Princic ◽  
...  

Introduction: Ethnical segregation and migration influence sexual health. Differences in sexual networks and the risk of sexually transmitted diseases (STDs) between racial/ethnic minorities and the native population have been described in the literature. Methodology: We collected data on sexual behavior and physical examination. Basing on CDC 2015 guidelines on STDs, anamnesis, and clinical features, screening for HIV/STDs was proposed. Results: We enrolled 209 migrants, the median age was 32.5 (26-40) years, and 146 (69.9%) were male. The most represented nationalities were Nigerian, Senegalese, and Somali, with 85 (40.7%), 68 (32.5%), and 16 (7.7%) people, respectively. Twenty-two (10.5%) patients referred perianal/genital lesions, 6 (2.9%) abdominal/pelvic discomfort, and 183 (87.6%) were asymptomatic. Almost all symptomatic patients accepted the tests. 52/183 (28.4%) asymptomatic subjects accepted the tests, and only 24/52(46.2%) performed them. Among symptomatic patients were 6 (24%) HBsAg positivities and one (4%) HCV infection. Four (16%) people had latent syphilis; in 12 (48%) people, HPV-related genital warts were present, 7 (28%) people had Molluscum contagiosum, and 6 (24%) women had pelvic inflammatory diseases. Among patients referring no symptoms, there were 10 (41.7%) HBsAg positivities, one (4.2%) HIV infection, four (16.7%) latent syphilis, one (4.2%) HPV-related genital infection, and one (4.2%) PID. Being Nigerian and having symptoms were associated with a more high acceptance of the STDs test. Having a high-risk behavior was significantly associated with the development of at least one STD. Conclusions: migrants have high-risk sexual behavior. Despite this, they have a low perception of HIV/STDs risk and healthcare needs. Particular attention should be given to improve access to HIV/STDs services that provide screening and treatment and increase the perception of healthcare needs.


2018 ◽  
Vol 10 (1) ◽  
pp. 32-39
Author(s):  
Yuli Fitriasih ◽  
Yuli Fitriasih ◽  
Nurhalim Shahib ◽  
Farid Husin

Abstract Sexually transmitted infections are infections that can be spread through vaginal, anal or oral. Female sex workers particularly at risk for sexually transmitted infections. Preliminary studies in Cilacap district STI clinic in 2011 showed that the incidence of sexually transmitted infections is still quite high (60.81%). Complex causal factors cause the difficulty of breaking the chain of IMS. This study aims to analyze the relationship between demographic factors and high-risk sexual behavior of high risk on the incidence of sexually transmitted infections and the risk factors on the incidence of sexually transmitted infections in female sex workers. Analytic survey research through case-control study (case-control) with a total sampling on 70 female sex workers in brothels Slarang conducted during the month of November 2013. Questionnaire as a means of collecting research data. Univariate analysis to determine the frequency distribution of incidence of STIs. Bivariate analysis using contingency coefficient test. Multivariate analysis using logistic regression. The results showed that there is a significant association between the incidence of STIs in high- risk demographic factors with r value (0.239) and p-value (0.040), there is a significant association between the incidence of STIs in high- risk sexual behavior factors with values ​​of r (0.307; 0.230) and the p-value ( 0.007; 0.048) respectively. Multivariate analysis showed that condom use is not routine is that most risk factors on the incidence of sexually transmitted infections in female sex workers with OR value 5.835. Conclusions of the study: female sex workers who do not regularly use condoms have 5.835 times greater risk for sexually transmitted infections. A total of 65% the proportion of female sex workers suffer preventable sexually transmitted infection, if condom use. Keywords : female sex workers, demographic factors, sexual behavior factors, sexually transmitted infections


2021 ◽  
Vol 8 (Supplement_1) ◽  
pp. S523-S523
Author(s):  
Mo Zhou ◽  
Yan Song ◽  
Emily Gao ◽  
Yohance Whiteside ◽  
Emma Billmyer ◽  
...  

Abstract Background To describe trends in emtricitabine and tenofovir disoproxil fumarate (FTC/TDF) PrEP uptake in 2012-2018 and characterize high risk individuals who use PrEP. Methods The study identified individuals aged ≥ 15 years old with claims suggesting high risk for HIV infection in the IBM MarketScan® Commercial Claims and Multi-state Medicaid Databases. High risk was defined using ICD codes indicating high risk sexual behavior or rectal/repeated bacterial sexually transmitted infection (STI). The index date was defined as the earliest of the first high risk sexual behavior diagnosis, the first rectal bacterial STI diagnosis, or the second non-rectal bacterial STI diagnosis within 12 months. Individuals were considered PrEP users if they had at least one FTC/TDF PrEP prescription within 12 months of index date. Individuals with evidence of HIV prior to or within 30 days after PrEP initiation/index date were excluded. Comorbidities were assessed using a modified Charlson Comorbidity Index that excluded HIV/AIDS. Results FTC/TDF PrEP uptake increased from 0.1% to 7.3% among commercially insured individuals between 2012-2018, and from 0.01% to 0.5% among Medicaid insured individuals between 2012-2017. Individuals ≥ 35 years old had the largest increase in PrEP uptake (0.1% to 13.0%), while those 16-25 years old had the smallest increase (0.03% to 2.3%). The largest proportion of PrEP users across all years were aged 25-34 while the largest proportion of non-PrEP users were aged 18-24. Compared to PrEP users, a larger proportion of PrEP non-users were female (62.9% vs. 1.4%, p < 0.05) and blacks/African American (49.1% vs. 40.3%, p < 0.05). A larger proportion of PrEP users had a risk status of homosexual (46.6% vs. 1.5%, p < 0.05) or bisexual (3.9% vs. 0.8%, p < 0.05) behavior than non-PrEP users. PrEP users also had more comorbidities than non-users among individuals with Medicaid and were less likely to have fee-for-service insurance plans overall (p < 0.05). Table 1. Characteristics of people at high-risk for HIV who do vs. do not use FTC/TDF PrEP measured during the follow-up period Conclusion Despite an increase in FTC/TDF PrEP initiations, uptake was low, especially among young adults, women, heterosexuals and blacks/African Americans. Low initiation rates in these groups may illustrate that FTC/TDF PrEP is not meeting the needs of all high-risk individuals. Disclosures Mo Zhou, PhD, Merck & Co., Inc. (Consultant) Yan Song, PhD, Merck & Co., Inc. (Consultant) Emily Gao, MS, MPH, Merck & Co., Inc. (Consultant) Yohance Whiteside, PhD, MSPH, Merck & Co., Inc. (Employee) Emma Billmyer, BA, Merck & Co., Inc. (Consultant) James Signorovitch, PhD, Merck & Co., Inc. (Consultant)


2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 5540-5540
Author(s):  
Ankur Bahl ◽  
Lalit Dar ◽  
BK Mohanti ◽  
Pankaj Kumar ◽  
Alok Thakar ◽  
...  

5540 Background: Among oropharyngeal squamous cell carcinoma (OSCC), the true prevalence of HPV remains variable and studies have estimated that up to 60% may be HPV positive. Patients with HPV positive tumor are usuallyyounger in age, less likely to have history of tobacco or alcohol consumption and associated with a better prognosis but this information for Indian patients is largely unknown. Methods: 105 newly diagnosed patients of OSCC were enrolled. HPV genotyping was done on the biopsy specimen by consensus polymerase chain reaction and reverse line-blot hybridization assay. HPV prevalence was studied according to gender, age, tobacco and alcohol use and high risk sexual behavior. Results: Overall HPV prevalence was 22.8%. HPV positive patients were younger by 8 years as compared to negative patients (P=0.003). No significant correlation between tobacco consumption, alcoholic habits, and HPV status was observed. The mean number of life time sexual partners in HPV positive patients was 1.66 while, it was 1.33 in HPV negative patients (P=0.049). Incidence of high risk sexual behaviors was more in HPV positive patients (P<0.001). There were no significant associations between the two groups with respect to tumor size, nodal stage and the overall stage of the tumor. 16% of the base of tongue cancers and 40% of tonsillar carcinoma were positive (P = 0.02). Among positive samples, HPV 16 was the commonest (79%) followed by HPV 18 (12%). 96% of patients received treatment. At 18.8 months there was no significant difference in OS, EFS between HPV positive and negative OSCC (P = 0.97 and P= 0.51 respectively). Conclusions: The current study reconfirms that HPV positive OSCC patients are younger with high risk sexual behavior. Impact of smoking and alcohol consumption on HPV status was not found in this study. HPV positive rates were significantly higher for tonsillar cancer. Contrary to literature, we did not find any differences in OS or EFS between two groups. Small numbers of patients in the study group, short follow up period and significant tobacco smoking in HPV group may be the one of the reason for this.


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