Study On Cardiovascular Disease Classification Using Machine Learning Approaches

Author(s):  
R. Subha
Author(s):  
Stuti Pandey ◽  
Abhay Kumar Agarwal

In a human body, the heart is the second primary organ after the brain. It causes either a long-term impairment or death of a person if suffering from a cardiovascular disease. In medical science, a proper medical analysis and examination of a cardiovascular disease is very crucial, convincing, and sophisticated task for saving a human life. Data analytics rises because of the absence of sufficient practical tools for exploring the trends and unknown relationships in e-health records. It predicts and achieves information which can ease the diagnosis. This survey examines cardiovascular disease prediction systems developed by different researchers. It also reviews the trend of machine learning approaches used in the past decade with results. Related studies comprise the performance of various classifiers on distinct datasets.


2021 ◽  
Author(s):  
Qian Zhou ◽  
Jia-Yi Yin ◽  
Wei-Yue Liang ◽  
Dong-Mei Chen ◽  
Qing Yuan ◽  
...  

Gout is a common inflammatory arthritis associated with various comorbidities, such as cardiovascular disease and metabolic syndrome.


Open Heart ◽  
2021 ◽  
Vol 8 (2) ◽  
pp. e001802
Author(s):  
Ashish Sarraju ◽  
Andrew Ward ◽  
Sukyung Chung ◽  
Jiang Li ◽  
David Scheinker ◽  
...  

ObjectivesIdentifying high-risk patients is crucial for effective cardiovascular disease (CVD) prevention. It is not known whether electronic health record (EHR)-based machine-learning (ML) models can improve CVD risk stratification compared with a secondary prevention risk score developed from randomised clinical trials (Thrombolysis in Myocardial Infarction Risk Score for Secondary Prevention, TRS 2°P).MethodsWe identified patients with CVD in a large health system, including atherosclerotic CVD (ASCVD), split into 80% training and 20% test sets. A rich set of EHR patient features was extracted. ML models were trained to estimate 5-year CVD event risk (random forests (RF), gradient-boosted machines (GBM), extreme gradient-boosted models (XGBoost), logistic regression with an L2 penalty and L1 penalty (Lasso)). ML models and TRS 2°P were evaluated by the area under the receiver operating characteristic curve (AUC).ResultsThe cohort included 32 192 patients (median age 74 years, with 46% female, 63% non-Hispanic white and 12% Asian patients and 23 475 patients with ASCVD). There were 4010 events over 5 years of follow-up. ML models demonstrated good overall performance; XGBoost demonstrated AUC 0.70 (95% CI 0.68 to 0.71) in the full CVD cohort and AUC 0.71 (95% CI 0.69 to 0.73) in patients with ASCVD, with comparable performance by GBM, RF and Lasso. TRS 2°P performed poorly in all CVD (AUC 0.51, 95% CI 0.50 to 0.53) and ASCVD (AUC 0.50, 95% CI 0.48 to 0.52) patients. ML identified nontraditional predictive variables including education level and primary care visits.ConclusionsIn a multiethnic real-world population, EHR-based ML approaches significantly improved CVD risk stratification for secondary prevention.


Oncogene ◽  
2021 ◽  
Author(s):  
Wencke Walter ◽  
Claudia Haferlach ◽  
Niroshan Nadarajah ◽  
Ines Schmidts ◽  
Constanze Kühn ◽  
...  

AbstractArtificial intelligence (AI) is about to make itself indispensable in the health care sector. Examples of successful applications or promising approaches range from the application of pattern recognition software to pre-process and analyze digital medical images, to deep learning algorithms for subtype or disease classification, and digital twin technology and in silico clinical trials. Moreover, machine-learning techniques are used to identify patterns and anomalies in electronic health records and to perform ad-hoc evaluations of gathered data from wearable health tracking devices for deep longitudinal phenotyping. In the last years, substantial progress has been made in automated image classification, reaching even superhuman level in some instances. Despite the increasing awareness of the importance of the genetic context, the diagnosis in hematology is still mainly based on the evaluation of the phenotype. Either by the analysis of microscopic images of cells in cytomorphology or by the analysis of cell populations in bidimensional plots obtained by flow cytometry. Here, AI algorithms not only spot details that might escape the human eye, but might also identify entirely new ways of interpreting these images. With the introduction of high-throughput next-generation sequencing in molecular genetics, the amount of available information is increasing exponentially, priming the field for the application of machine learning approaches. The goal of all the approaches is to allow personalized and informed interventions, to enhance treatment success, to improve the timeliness and accuracy of diagnoses, and to minimize technically induced misclassifications. The potential of AI-based applications is virtually endless but where do we stand in hematology and how far can we go?


2020 ◽  
Vol 10 (5) ◽  
pp. 1005-1022 ◽  
Author(s):  
Shahan Yamin Siddiqui ◽  
Atifa Athar ◽  
Muhammad Adnan Khan ◽  
Sagheer Abbas ◽  
Yousaf Saeed ◽  
...  

Background: To provide ease to diagnose that serious sickness multi-technique model is proposed. Data Analytics and Machine intelligence are involved in the detection of various diseases for human health care. The computer is used as a tool by experts in the medical field, and the computer-based mechanism is used to diagnose different diseases in patients with high Precision. Due to revolutionary measures employed in Artificial Neural Networks (ANNs) within the research domain in the medical area, which appear to be in the data-driven applications usually described in the domain of health care. Cardio sickness according to name is a type of an ailment that is directly connected to the human heart and blood circulation setup, so it should be diagnosed on time because the delay of diagnosing of that disease may lead the sufferer to death. The research is mainly aimed to design a system that will be able to detect cardiovascular sickness in the sufferer using machine learning approaches. Objective: The main objective of the research is to gather information of the six parameters that is age, chest pain, electrocardiogram, systolic blood pressure, fasting blood sugar and serum cholesterol are used by Mamdani fuzzy expert to detect cardiovascular sickness. To propose a type of device which will be successfully used in overcoming the cardiovascular diseases. This proposed model Diagnosis Cardiovascular Disease using Mamdani Fuzzy Inference System (DCD-MFIS) shows 87.05 percent Precision. To delineate an effective Neural Network Model to predict with greater precision, whether a person is suffering from cardiovascular disease or not. As the ANN is composed of various algorithms, some will be handed down for the training of the network. The main target of the research is to make the use of three techniques, which include fuzzy logic, neural network, and deep machine learning. The research will employ the three techniques along with the previous comparisons, and given that, the results will be compared respectively. Methods: Artificial neural network and deep machine learning techniques are applied to detect cardiovascular sickness. Both techniques are applied using 13 parameters age, gender, chest pain, systolic blood pressure, serum cholesterol, fasting blood sugar, electrocardiogram, exercise including angina, heart rate, old peak, number of vessels, affected person and slope. In this research, the ANN-based research is one of the algorithms collections, which is the detection of cardiovascular diseases, is proposed. ANN constitutes of many algorithms, some of the algorithms are employed in the paper for the training of the network used, to achieve the prediction ratio and in contrast of the comparison of the mutual results shown. Results: To make better analysis and consideration of the three frameworks, which include fuzzy logic, ANN, Deep Extreme Machine Learning. The proposed automated model Diagnosis Cardiovascular Disease includes Fuzzy logic using Mamdani Fuzzy Inference System (DCD-MFIS), Artificial Neural Network (DCD–ANN) and Deep Extreme Machine Learning (DCD–DEML) approach using back propagation system. These frameworks help in attaining greater precision and accuracy. Proposed DCD Deep Extreme Machine Learning attains more accuracy with previously proposed solutions that are 92.45%. Conclusion: From the previous comparisons, the propose automated Diagnosis of Cardiovascular Disease using Fuzzy logic, Artificial Neural Network, and deep extreme machine learning approaches. The automated systems DCDMFIS, DCD–ANN and DCD–DEML, the framework proposed as effective and efficient with 87.05%, 89.4% and 92.45 % success ratios respectively. To verify the performance which lies in the ANNs and computational analysis, many indicators determining the precise performance were calculated. The training of the neural networks is made true using the 10 to 20 neurons layers which denote the hidden layer. DEML reveals and indicates a hidden layer containing 10 neurons, which shows the best result. In the last, we can conclude that after making a consideration among the three techniques fuzzy logic, Artificial Neural Network and Proposed DCD Deep Extreme Machine, the Proposed DCD Deep Extreme Machine Learning based solution give more accuracy with previously proposed solutions that are 92.45%.


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