scholarly journals The Pattern of Ocular Morbidity in a Tertiary Care Hospital in North India-A Hospital Based Cross-Sectional Study

Author(s):  
Dr Pooja Kanodia ◽  
Author(s):  
Shivani Juneja ◽  
Proteesh Rana ◽  
Parvinder Chawala ◽  
Rekha Katoch ◽  
Kulvir Singh ◽  
...  

Abstract Objectives The use of Hydroxychloroquine (HCQ) prophylaxis has been recommended by the National task force constituted by the Indian Council of Medical Research (ICMR) for the prevention of corona virus disease 2019 (COVID-19) among healthcare workers (HCWs). However, this recommendation was based essentially on the preclinical data and limited clinical experience. The aim of this study was to evaluate the efficacy and safety of HCQ as a pre-exposure prophylaxis for COVID-19 infection among Indian HCWs. Methods A cross-sectional study was conducted among HCWs of a tertiary care hospital in north India. The HCQ prophylaxis was initiated among 996 HCWs and they were followed up to 8 weeks for conversion to COVID-19 positive status and any adverse drug reaction (ADR). Results About 10.3% of the study participants were tested positive for COVID-19 which was comparable to the positivity rate among HCWs not taking HCQ prophylaxis (9.7%). Conclusions HCQ was well tolerated at a weekly dose of 400 mg for 8 weeks but provided no additional benefit in prevention of COVID-19 among HCWs.


2021 ◽  
Vol 59 (244) ◽  
pp. 1219-1224
Author(s):  
Pradeep Bastola ◽  
Polina Dahal

Introduction: Due to the ongoing coronavirus disease 2021 pandemic and lockdown, eye care services have been compromised globally. The magnitude of ocular diseases across all populations in Nepal are few and far between and rare during this pandemic. This study was aimed to find out the prevalence of ocular morbidity among patients visiting the department of Ophthalmology of a tertiary care hospital during the pandemic. Methods: A descriptive cross-sectional study was conducted among the patients visiting thedepartment of Ophthalmology of a tertiary care hospital from 18 August 2021 to 30 September 2021. Ethical clearance was taken from the Institutional Review Committee (Reference: 078/079-023). Convenience sampling was done. Basic demographic data, clinical characteristics, visual status and prevalence of ocular morbidities were noted. Data entry was done using Statistical Package for the Social Sciences version 26. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data. Results: Out of 650 study subjects examined, 454 (69.8%) (66-73.0 at 95% Confidence Interval) study subjects had at least one ocular morbidity in at least one eye. Refractive error 153 (33.7%) was the commonest ocular morbidity followed by headache 52 (11.5%), dry eyes 50 (11%), non-communicable diseases related ocular morbidity 41 (9%), and age related cataract 37 (8.1%). Conclusions: The prevalence of ocular morbidity in our study was higher than findings from other similar studies done at national and international levels, though the causes of ocular morbidity was similar.


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