scholarly journals Risk Factors for Depression in Elderly Persons Attending the General Outpatient Clinics of the University of Uyo Teaching Hospital, Uyo

Author(s):  
Uduakobong Morgan ◽  
2020 ◽  
Vol 61 (3) ◽  
pp. 120
Author(s):  
UwemedimbukSmart Ekanem ◽  
EmemIme Dan ◽  
GeorgeGeorge Etukudo ◽  
IdongesitIbanga Ndon ◽  
EkeminiEssien Etebom ◽  
...  

2017 ◽  
Vol 23 (1) ◽  
pp. 187
Author(s):  
Elvis Mbu Bisong ◽  
Henry Ohem Okpa ◽  
Udoezuo Kingsley Ogbonna ◽  
Ofem Egbe Enang ◽  
Emmanuel Monjok

Author(s):  
Inye Faye Korubo ◽  
Justina Omoikhefe Alegbeleye ◽  
Chris Iheanachor Akani

Aim: To identify the microorganisms in urine before and after delivery. Also, to identify the incidence, risk factors and antibiotic susceptibility pattern in postpartum bacteriuria.      Methods: A quasi-interventional study of 50 women who had term vaginal deliveries at the University of Port Harcourt Teaching Hospital (UPTH) Nigeria, between September 1, 2016 and December 31, 2016. Clean catch midstream urine samples collected in sterile containers from parturients before and after delivery were processed. All significant isolates were subjected to antimicrobial susceptibility testing. Socio-demographic data and data regarding labour and risk factors were collected on a pre-designed proforma and entered on a spread sheet. Statistical analysis was done using SPSS version 22.0. Results: Majority 49 (98%) of the parturients were booked (women that received antenatal care). Eight (16%) of the parturients had bacteriuria pre and post-delivery. Four of the parturients who were negative for bacteriuria before delivery had postpartum bacteria, giving an incidence of 8% for postpartum bacteriuria. The commonest micro-organism isolated post-delivery was Escherichia coli (50%). The number of vaginal examinations, vacuum delivery, episiotomy, perineal tear and bladder catheterization did not significantly increase the risk of postpartum bacteriuria. Conclusion: Escherichia coli is the most common urinary pathogens and sensitive to Nalidixic acid. Routine screening of women for bacteriuria after delivery and an understanding of the antimicrobial sensitivity will help in reducing associated morbidities.


2019 ◽  
Author(s):  
PRISCILLA KAPOMBE ◽  
LUNGOWE SITALI ◽  
PATRICK MUSONDA

Abstract Background Neisseria gonorrhea, the causative agent of Gonorrhea, has developed antibiotic resistance to the “last-line” Cephalosporin’s, Quinolones and Macrolides which is cause for concern. In Zambia, despite recommendations of discontinued use, Ciprofloxacin is used for treatment. The lack of an active surveillance system, appropriate and structured data management and analysis tools magnifies the problem because resistance patterns cannot be monitored. The study aimed to ascertain effectiveness of Ciprofloxacin a Quinolone in comparison with Ceftriaxone a Cephalosporin, in treatment of Gonorrhea using Susceptibility testing; and to identify possible risk factors associated with resistance. Methods Study design was parallel non-inferior quasi experimental study. Patients at the University Teaching Hospital with discharge and Gonorrhea symptoms who gave consent, were recruited. Fishers Exact Test for associations was used. Data was analyzed using Ordinal logistic regression as the Susceptibility was at 3 levels; Susceptible, Intermediate or Resistant with an assumed Ordinal nature. Proportionality assumption was checked, and when violated Partial Proportional Odds Model was used instead. Results A total of 104 isolates were obtained. The overall proportion of patients who had Susceptible, Intermediate and Resistant results were: 49 (47.1%), 55 (52.9%) and 0 (0) for Ceftriaxone and 70 (68.0%), 10 (9.7%) and 22 (22.3%) for Ciprofloxacin respectively. Adjusted estimates in partial Proportional Odds model showed that, Males were 4.1 (95% CI; 1.8, 9.4, p-value=0.001) times more likely to have Intermediate or Susceptible results compared to Resistance than females, or they were more likely to have Susceptible compared to Resistance or Intermediate result compared to females. Ciprofloxacin was 70% less likely than Ceftriaxone of having susceptible or intermediate results compared to resistance and this could be as high as 90% and as high as 40% p-values <0.001). Conclusion Level of Ciprofloxacin resistance detected from the Susceptibility testing, shows it is not an effective treatment for Gonorrhea. Ceftriaxone remains a satisfactory option for first-line treatment of Gonorrhea at UTH. Risk factors identified to be associated with resistance in this study were being female and use of Ciprofloxacin. Ethical Clearance Ethical clearance was obtained from University of Zambia Biomedical Ethics Research Committee (UNZABREC Ref # 033-06-17).


Author(s):  
Nchimunya Machila ◽  
◽  
Chishala Chabala ◽  
Chisambo Mwaba ◽  
Catherine Chunda-Liyoka ◽  
...  

Background: Improved medical care has led to the improved life expectancy of sickle cell anaemia (SCA) patients hence complications associated with SCA such as chronic kidney disease (CKD) are being seen more frequently. Globally, nephropathy of varying severity occurs in 5 to 18 % of the SCA population across all age groups with a third of the adults proceeding to develop CKD while over 30 % of paediatric SCA patients have CKD in Africa. The mortality rate in SCA patients CKD is high. This study sought to determine the prevalence and risk factors of CKD in SCA, information that was not available in Zambia prior to this study. This information will guide in targeting and timing of screening for CKD in SCA in children in our population. Objectives: To determine the prevalence of haematuria, proteinuria, abnormal estimated glomerular filtration rate (eGFR), CKD, and risk factors of CKD among the steady-state SCA patients aged 5 to 16 years at the University Teaching Hospital (UTH), Lusaka. Methodology: This was a prospective cross-sectional study of 197 children aged 5 to 16 years with SCA at the UTH - Lusaka conducted from August 2014 to July 2015. Demographic and clinical data were collected using a structured questionnaire. Urine and blood samples were used to determine the urine albumin creatinine ratio (ACR) and full blood count /blood biochemistry respectively. CKD was defined and determined using the Kidney Disease Outcome Quality Initiative 2012 guidelines employing urine ACR, dipstick urinalysis and eGFR. In this study, spot urine ACR and dipstick urinalysis were done and repeated three months later if initial tests were abnormal. Data was analysed using SPSS version 21. Chi-square and t-test were used to compare proportions between groups. Relation between study variables and CKD were examined using logistic regression. Results: The mean age of the participants was 9.6 years (SD ±3.6). Male to female ratio was 1:1. The median age at diagnosis of SCA was 22 months (IQR = 44). The prevalence of haematuria, proteinuria and CKD among the study participants was 14.2%, 36% and 36 % respectively. Low haemoglobin and elevated mean corpuscular volume (MCV) were associated with CKD-AOR 0.62, 95% CI; 0.46-0.84 and 1.04, 95% CI; 1.01 – 1.08 respectively. Recurrent admissions (due to VOCs, severe anaemia and febrile illness) were also risk factors associated with CKD- AOR 0.52, 95% CI; 0.27-0.98. CKD was not associated with age at enrolment, sex, age at diagnosis of SCA, recurrent Vaso-occlusive crisis (VOCs) or abnormal liver function tests. Conclusion: The prevalence of CKD among the SCA patients at UTH- Lusaka is high (36%) with lower Haemoglobin, elevated MCV and recurrent admissions being risk factors for developing CKD. SCA patients should be screened for CKD routinely at least once a year. Interventions such as the early introduction of hydroxyurea, proactive blood transfusions and ACE inhibitors can reduce the risk of CKD and its progression to end-stage renal disease.


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