Myringoplasty with Autologous Platelet Rich Plasma -A Prospective Study

Background: Platelet-rich plasma (PRP) is a natural concentrate of autologous blood growth factors experimented in different fields of medicine in order to test its potential to enhance tissue regeneration. The aim of our study is to study the effects of intra articular injections of autologous “Platelet Rich Plasma“ in the osteoarthritis of knee joint and to assess the functional outcome after injecting platelet rich plasma in osteoarthritic knee joints and compare the results with standard studies and draw conclusions.Methods: This is a prospective study done on 161 Kellgren-Lawrence radiological grade I and grade II knee joints, between August 2013 and March 2016 which, were treated with PRP intra-articular injections. The procedure consisted of injection of 8 ml platelet concentrate into the knee joint with an 18- gauge needle without local anaesthetic. Patients were assessed with WOMAC (Western Ontario McMaster Universities Arthritis Index) scoring pre injection of PRP and post injection period of 1 month and 6 months. A reduction in WOMAC score is suggestive of improvement in the patient’s condition.Results: There is a significant improvement in WOMAC score of all the patients and the results sustained for more than 6 months. Though there is clinically better results are seen in grade I knee joints than grade II knee joints, these results are statistically not significant.Conclusions: Osteoarthritis (Grade I and Grade II) of Kellgren Lawrence radiological grading does give relief from pain, stiffness and improves functionality without any major side effects and can be recommended as a viable modality of treatment.

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Effect of autologous platelet-rich plasma on clinical outcome in patients with suboptimal endometrium in fresh ICSI/FET cycle − an interventional prospective study

Fertility Science and Research ◽

10.4103/2394-4285.288718 ◽

2020 ◽

Vol 7 (1) ◽

pp. 70

Author(s):

Jyoti Gupta ◽

Bharti Jain ◽

Kuldeep Jain

Keyword(s):

Clinical Outcome ◽

Prospective Study ◽

Platelet Rich Plasma ◽

Autologous Platelet Rich Plasma ◽

Autologous Platelet

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Treatment with platelet-rich plasma of surgically related dormant corneal ulcers

European Journal of Ophthalmology ◽

10.1177/1120672117747042 ◽

2018 ◽

Vol 28 (5) ◽

pp. 515-520 ◽

Cited By ~ 11

Author(s):

Jorge L Alio ◽

Alejandra E Rodriguez ◽

Pablo De Arriba ◽

Sandra Gisbert ◽

Ahmed A Abdelghany

Keyword(s):

Platelet Rich Plasma ◽

Corneal Edema ◽

Rank Test ◽

Eye Drops ◽

Corneal Surgery ◽

Corneal Ulcers ◽

Signed Rank Test ◽

Autologous Platelet Rich Plasma ◽

A Prospective Study ◽

Autologous Platelet

Purpose: To assess the effectiveness of autologous platelet-rich plasma for the treatment of dormant corneal ulcers secondary to corneal surgery and unresponsive to conventional treatment. Setting: VISSUM, Ophthalmology Institute of Alicante, Alicante, Spain. Design: Prospective nonrandomized, observational consecutive study. Methods: A total of 44 eyes of 28 patients with dormant corneal ulcers secondary to corneal surgery were included in a prospective study and treated with autologous platelet-rich plasma during 6 weeks. Wilcoxon signed-rank test was used to compare the effect of the treatment. Results: In all, 28 patients (65.1%) improved their visual acuity at least one line in Snellen chart, 26 (59.09%) had a decrease in the size of the ulcer or even a total closure, and 40 (90.9%) experienced an improvement in their symptoms. The results are also provided for the four groups of patients (keratoplasty, refractive surgery, cross-linking, and chronic postsurgical corneal edema). Conclusion: Platelet-rich plasma eye drops shows to be a good option for the treatment of dormant corneal ulcers secondary to corneal surgery.

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