scholarly journals Role of Amniotic Membrane Transplantation in Brittle Cornea Syndrome-A Case Report

2020 ◽  
Vol 08 (01) ◽  
Author(s):  
Dr Prasanta Kumar Nanda ◽  
2013 ◽  
Vol 34 (3) ◽  
pp. 485-491 ◽  
Author(s):  
Shalini Mohan ◽  
Ina Budhiraja ◽  
Amit Saxena ◽  
Perwez Khan ◽  
S. K. Sachan

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Sheelah F. Antao ◽  
Tariq Ayoub ◽  
Hasan Tahir ◽  
Dipak N. Parmar

Purpose. To report the use of infliximab in the rapid stabilization of a case of progressive, bilateral rheumatoid peripheral ulcerative keratitis (PUK) that failed to respond to conventional immunosuppressive therapy.Methods. A single interventional case report.Results. A patient with rheumatoid arthritis presented with bilateral PUK following a 2-month history of ocular discomfort and redness. His systemic prednisolone (PDN) and methotrexate (MTX) were increased and, despite an initial favorable response, bilateral recurrent corneal perforations ensued. Both eyes underwent cyanoacrylate glue repair, amniotic membrane transplantation (AMT), and penetrating keratoplasty (PKP). Recurrence of the disease and bilateral perforations of the second PKP in both eyes prompted administration of intravenous infliximab immediately after the fourth PKP. The disease activity rapidly settled in both eyes, and at eighteen-month followup, after 12 infliximab infusions, the PUK remains quiescent with no further graft thinning or perforation.Conclusion. Infliximab can be used to arrest the progression of severe bilateral rheumatoid PUK in cases that are refractory to conventional treatment.


Ophthalmology ◽  
2016 ◽  
Vol 123 (3) ◽  
pp. 484-491 ◽  
Author(s):  
Namrata Sharma ◽  
S.A. Thenarasun ◽  
Manpreet Kaur ◽  
Neelam Pushker ◽  
Neena Khanna ◽  
...  

2013 ◽  
Vol 53 (4) ◽  
pp. 33-41 ◽  
Author(s):  
Kristine Lo ◽  
Sahar Kohanim ◽  
Danielle Trief ◽  
James Chodosh

2021 ◽  
Author(s):  
Farhad Nejat ◽  
Khosrow Jadidi ◽  
Shima Eghtedari ◽  
Maryam Moradi ◽  
Nazanin Sadat Nabavi

Abstract Background: conjunctival nevi are benign ocular lesions with a low risk of malignant transformation to melanoma. Due to cosmetic reasons patients usually consider surgical removal options. In this case report, we are presenting a new approach using plasma-assisted noninvasive surgery (PANIS) with amniotic membrane transplantation (AMT) to sublimate the nevus border and fuse the AMT with the remaining conjunctiva.Case presentation: A 33-year-old man with a history of large conjunctival nevus in his left eye, that its benignity was proved by an expert ophthalmologist through years of examination, has visited our center in September 2020. Plasma spots were used to sublimate the nevus border and fuse AMT with the conjunctiva. The patient was discharged fully satisfied without any complications and no recurrences were seen in a year of follow-up. Visual parameters were not significantly changed while the Ocular Surface Disease Index (OSDI) was reduced dramatically. Conclusion: Conjunctival nevi removal using the PANIS method with AMT is a safe, minimally invasive, and inexpensive therapeutic option. Plasma spots are suitable for AMT adhesion to the remaining conjunctiva after the nevus removal.


‘Conjunctiva’ provides the reader with a practical approach to the assessment and management of conjunctival disease. After outlining the relevant anatomy and physiology of this structure, the chapter addresses the key clinical presentations arising from conjunctival disease, notably infective conjunctivitis (including bacterial, viral and chlamydial), allergic conjunctivitis, cicatricial conjunctivitis, dry eyes and conjunctival lesions. Using a patient-centred approach the key clinical features, investigations and treatment (medical and surgical) are described for each condition. There is also extended discussion around the role of amniotic membrane transplantation and corneal transplantation.


2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Antonio Fea ◽  
Paola Maria Loredana Cannizzo ◽  
Giulia Consolandi ◽  
Carlo Alessandro Lavia ◽  
Giulia Pignata ◽  
...  

Traditional options in managing failed trabeculectomy (bleb needling, revision, additional incisional surgery and tube surgery) have a relatively high failure and complication rate. The use of microinvasive glaucoma surgery (MIGS) has generally been reserved to mild to moderate glaucoma cases, proving good safety profiles but significant limitations in terms of efficacy. We describe a patient who underwent MIGS (XEN Aquesys subconjunctival shunt implantation) after a prior failed trabeculectomy. After the surgery, the IOP was well controlled but as the stent was close to an area of scarred conjunctiva of the previous trabeculectomy, it became partially exposed. As a complete success was achieved, we decided to remove the conjunctiva over the exposed area and replace it by an amniotic membrane transplantation and a conjunctiva autograft. Six months after surgery, the unmedicated IOP is still well controlled with complete visual acuity recovery.


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