scholarly journals Evaluation of Plasma-Assisted Noninvasive Surgery (PANIS) as a New Technique for Sublimating Large Benign Conjunctival Nevus with Amniotic Membrane Transplantation (AMT); A Clinical Case Report

2021 ◽  
Author(s):  
Farhad Nejat ◽  
Khosrow Jadidi ◽  
Shima Eghtedari ◽  
Maryam Moradi ◽  
Nazanin Sadat Nabavi
Keyword(s):  
Case Report ◽  
Amniotic Membrane ◽  
Therapeutic Option ◽  
Amniotic Membrane Transplantation ◽  
Surgical Removal ◽  
Ocular Surface Disease Index ◽  
Noninvasive Surgery ◽  
Ocular Lesions ◽  
History Of ◽  
A New Technique

Abstract Background: conjunctival nevi are benign ocular lesions with a low risk of malignant transformation to melanoma. Due to cosmetic reasons patients usually consider surgical removal options. In this case report, we are presenting a new approach using plasma-assisted noninvasive surgery (PANIS) with amniotic membrane transplantation (AMT) to sublimate the nevus border and fuse the AMT with the remaining conjunctiva.Case presentation: A 33-year-old man with a history of large conjunctival nevus in his left eye, that its benignity was proved by an expert ophthalmologist through years of examination, has visited our center in September 2020. Plasma spots were used to sublimate the nevus border and fuse AMT with the conjunctiva. The patient was discharged fully satisfied without any complications and no recurrences were seen in a year of follow-up. Visual parameters were not significantly changed while the Ocular Surface Disease Index (OSDI) was reduced dramatically. Conclusion: Conjunctival nevi removal using the PANIS method with AMT is a safe, minimally invasive, and inexpensive therapeutic option. Plasma spots are suitable for AMT adhesion to the remaining conjunctiva after the nevus removal.

scholarly journals Stabilization of Bilateral Progressive Rheumatoid Corneal Melt with Infliximab

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Sheelah F. Antao ◽  
Tariq Ayoub ◽  
Hasan Tahir ◽  
Dipak N. Parmar
Keyword(s):  
Rheumatoid Arthritis ◽  
Case Report ◽  
Amniotic Membrane ◽  
Conventional Treatment ◽  
Penetrating Keratoplasty ◽  
Amniotic Membrane Transplantation ◽  
Cyanoacrylate Glue ◽  
Ocular Discomfort ◽  
History Of ◽  
Ulcerative Keratitis

Purpose. To report the use of infliximab in the rapid stabilization of a case of progressive, bilateral rheumatoid peripheral ulcerative keratitis (PUK) that failed to respond to conventional immunosuppressive therapy.Methods. A single interventional case report.Results. A patient with rheumatoid arthritis presented with bilateral PUK following a 2-month history of ocular discomfort and redness. His systemic prednisolone (PDN) and methotrexate (MTX) were increased and, despite an initial favorable response, bilateral recurrent corneal perforations ensued. Both eyes underwent cyanoacrylate glue repair, amniotic membrane transplantation (AMT), and penetrating keratoplasty (PKP). Recurrence of the disease and bilateral perforations of the second PKP in both eyes prompted administration of intravenous infliximab immediately after the fourth PKP. The disease activity rapidly settled in both eyes, and at eighteen-month followup, after 12 infliximab infusions, the PUK remains quiescent with no further graft thinning or perforation.Conclusion. Infliximab can be used to arrest the progression of severe bilateral rheumatoid PUK in cases that are refractory to conventional treatment.

Evaluation of Plasma-Assisted Noninvasive Surgery (PANIS) As a New Approach for Pterygium Removal with Amniotic Membrane Transplantation (AMT); a Clinical Case Series

2021 ◽  
Vol 6 (11) ◽  
pp. 808-813
Author(s):  
Farhad Nejat ◽  
Khosrow Jadidi ◽  
Shima Eghtedari ◽  
Nazanin Sadat Nabavi ◽  
Maryam Moradi
Keyword(s):  
Visual Acuity ◽  
Amniotic Membrane ◽  
Surgical Procedure ◽  
Clinical Case ◽  
Case Series ◽  
Cost Benefit ◽  
Amniotic Membrane Transplantation ◽  
Ocular Surface Disease Index ◽  
Noninvasive Surgery ◽  
Uncorrected Visual Acuity

Purpose: Medical plasma application has been used in different fields recently. In this study, we assess the outcome of using plasma-assisted noninvasive surgery (PANIS) with amniotic membrane transplantation (AMT) in pterygium surgical treatment. Methods: This clinical case series was conducted in 4 patients with primary grades 1, 2, and 3 pterygium (Table 1). After exclusion and inclusion criteria considerations, patients underwent different examinations. Various measurements were obtained such as uncorrected visual acuity (UCVA), refractive error (RE), the best-corrected visual acuity (BCVA), and ocular surface disease index (OSDI). The surgical procedure was pterygium removal from the cornea and then AMT attached to the conjunctival borders with plasma spots using a white handpiece of Plexr device (Plexr, GMV s.r.l Grottaferrata, Italy) instead (Table 2). After postoperative follow-ups within the first week of the surgery and in 1 month and 6 months later the results were obtained. Results: All patients have been fully recovered after the surgery without any complications. In all 4 cases, UCVA, BCVA, and RE parameters have improved during 6 months after the surgical procedure. Every patients’ OSDI decreased after the surgery. Recurrence has not been seen in any cases during 6 months follow-up. Conclusion: Pterygium removal surgery using the PANIS technique with AMT is safe, effective, fast, and cost-benefit.

scholarly journals Case Report. Extracorporeal Membrane Oxygenation in Nivolumab Associated Pneumonitis

2017 ◽  
Vol 3 (2) ◽  
pp. 84-88
Author(s):  
Thomas-Michael Schneider ◽  
Friederike Klenner ◽  
Franz Brettner
Keyword(s):  
Case Report ◽  
Extracorporeal Membrane Oxygenation ◽  
Therapeutic Option ◽  
High Dose ◽  
Great Success ◽  
Case Presentation ◽  
Computed Tomographic ◽  
Rehabilitation Hospital ◽  
Membrane Oxygenation ◽  
History Of

Abstract Background: Newly approved immunotherapeutic agents, like CTLA-4 inhibitors and antibodies against PD-1, are a promising therapeutic option in cancer therapy. Case presentation: A 74-year-old man, with a history of advanced stage melanoma and treatment with ipilimumab, pembrolizumab and nivolumab, was admitted to the hospital due to respiratory failure with hypoxemia and dyspnoea. He rapidly developed severe acute respiratory distress syndrome (ARDS), which required treatment in the intensive care unit which included mechanical ventilation and extracorporeal membrane oxygenation (ECMO). Computed tomographic imaging (CT) showed signs of a pneumonitis, with an ARDS pattern related to the use of PD-1 antibodies. Treating the patient with high-dose immunosuppressive steroids led to an overall improvement. He was transferred to a rehabilitation hospital and subsequently to his home. Discussion and conclusion: This is a unique case report of a patient suffering a grade 4 adverse event under nivolumab who survived having been treated with ECMO. It highlights the possibility of associated adverse reactions as well as the use of ECMO in palliative care patients. ECMO can be of great success even in patients with malignancies, but careful decision making should be done on a case by case basis.

scholarly journals First Autochthonous Infection of a Cat with Dirofilaria immitis in Austria

Pathogens ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 1104 ◽  
Author(s):  
Lisa-Maria Kulmer ◽  
Maria Sophia Unterköfler ◽  
Hans-Peter Fuehrer ◽  
Varvara Janovska ◽  
Matus Pagac ◽  
...  
Keyword(s):  
Case Report ◽  
Dirofilaria Immitis ◽  
Complete Blood Count ◽  
Clinical Signs ◽  
Surgical Removal ◽  
Negative Results ◽  
Heartworm Disease ◽  
History Of ◽  
One Year ◽  
The Right

This case report is about a seven-year-old male neutered European Shorthair cat infected by Dirofilaria immitis as the first reported autochthonous Dirofilaria immitis infection in Austria. There was no history of periods abroad. Echocardiography showed suspected D. immitis in the right cardiac chamber with increased pulmonary pressure and ascites. Surgical removal of the heartworms was performed. Twenty adult heartworms were removed by transvenous jugular approach under general anesthesia and stored in 4% formalin. Five out of 20 specimens were examined via light and stereomicroscopy and feline heartworm infection was confirmed. Amplification of a 203 bp or 724 bp fragment of the cytochrome c oxidase subunit I gene was unsuccessful. After surgery the cat developed acute renal failure but recovered quickly. One year later, the cat underwent a control examination including echocardiography and blood work. There were no more D. immitis detectable at echocardiography. Lung pressure was mildly increased. Complete blood count and creatinine were unremarkable. The Knott’s test and Dirofilaria-Antigen-test produced negative results. The cat did not show any clinical signs during the follow-up period. The aim of this case report is to highlight the growing risk of acquiring infection with D. immitis not only for Austrian dogs, but also for cats. This case report represents the first report of autochthonous D. immitis infection in Austria. Moreover, even if the prognosis in cats with caval syndrome due to feline heartworm disease is guarded to poor, surgical removal of the filariae can be a successful treatment option.

Vortioxetine Efficiency in Controlling Obsessive Symptoms in Patients with Depression. A Case Report

2017 ◽  
Vol 41 (S1) ◽  
pp. S715-S715
Author(s):  
G. Pardo de Santayana ◽  
R. Landera ◽  
M. Juncal ◽  
O. Porta ◽  
L. Sánchez ◽  
...  
Keyword(s):  
Case Report ◽  
Sexual Dysfunction ◽  
Sexual Function ◽  
Depressive Episode ◽  
Therapeutic Option ◽  
Recurrent Depression ◽  
Patient Reported ◽  
History Of ◽  
Competing Interest ◽  
Stress At Work

IntroductionObsessive symptomatology can sometimes be worsened when a patient with this personality trait suffers through a period of increased stress.AimTo review articles in PubMed related to how vorticoxetine affects obsessive symptoms in patients with depression.MethodsWe review the case of a 45-year-old male with obsessive personality traits diagnosed of recurrent depression. He was going through a period of stress at work that had worsened his obsessive symptoms (primarily obsessive thoughts). In a previous depressive episode, he was treated with an antidepressant that triggered sexual dysfunction as a side effect. Trying to prevent another antidepressant-induce sexual dysfunction, we decided to use voricoxetine because of its low tendency to interact with the sexual function.ResultsWe started treatment with vorticoxetine reaching a dose of 10 mg/day. Three weeks later the patient reported a decrease in his levels of anxiety, a slight upturn of his mood and a relieve of his obsessive symptoms.ConclusionsVorticoxetine can be considered a good therapeutic option in the treatment of obsessive symptoms in a depressive episode with patients with a history of antidepressant-induce sexual dysfunction.Disclosure of interestThe authors have not supplied their declaration of competing interest.

Ossification of the Achilles Tendon: A Case Report

1994 ◽  
Vol 15 (1) ◽  
pp. 44-47 ◽  
Author(s):  
Masahito Hatori ◽  
Atsushi Kita ◽  
Yoshinori Hashimoto ◽  
Nikichi Watanabe ◽  
Minoru Sakurai
Keyword(s):  
Case Report ◽  
Achilles Tendon ◽  
Previous History ◽  
Rare Condition ◽  
Chief Complaint ◽  
Surgical Removal ◽  
Intramembranous Ossification ◽  
History Of ◽  
Bony Mass ◽  
The Right

Ossification of the Achilles tendon is a rare condition. We recently treated a patient with ossification of bilateral Achilles tendons. The patient was a 50 year old male whose chief complaint was discomfort around the Achilles tendon. He had a previous history of treatment of bilateral club feet On the roentgenograms, the length of the bony mass in the Achilles tendon was 5.5 cm on the right side and 1.5 cm on the left side. The left side was treated by surgical removal of a bony mass and suture of the tendon. Microscopic examination of the extirpated specimen revealed bone formation through enchondral and intramembranous ossification in the Achilles tendon.

Sign in / Sign up

Export Citation Format

Share Document