Publicly Available Data-Based Flood Risk Assessment Methodology: A Case Study for a Floodplain in Poland

Flood risk assessment is used to estimate the expected consequences and probability of a flood. It leads to the strengthening of resilience through appropriate preparation for an event of a specific scale. The methodology described in this paper was developed by the authors for the purposes of flood risk assessment in Poland, introduced to and applied on an actual example. It is based on simple calculations and a comparison of the results with a template. All of the data required for calculation came from freely available sources. Therefore, it is essential to evaluate the effectiveness of the flood risk assessment methodology in improving construction safety and identifying the factors that influence its implementation. The approach presented in this article is based on implementation of the parameters of floods, describing the characteristics of the exposed area and human vulnerability, among other factors, to the national risk assessment methodology, and then using it to determine the directions of activities aimed at reducing the risk of flooding. Simultaneously, assessment of these parameters might not be related directly to flood threats, but rather to the broader approach to risk assessment, including other threats. As a result of the application of the described methodology, it was estimated that the flood risk in the studied area is catastrophic, which requires immediate decisions of people responsible for safety.

Novel 60 GHz Band Spatial Synthetic Exposure Setup to Investigate Biological Effects of 5G and Beyond Wireless Systems on Human Body

The global spread of 5th generation (5G) wireless systems causes some concern about health effects of millimeter waves (MMW). To investigate biological effects of local exposure to 5G-MMW on human body, a novel 60 GHz band exposure setup was developed, and its performance was validated. A spatial synthetic beam-type exposure setup using two dielectric lens antennas was proposed to achieve high intensity 60 GHz irradiation to the target area of human skin. Variety distributions and intensities of electromagnetic fields at the exposed area, which is modified by incident angles of the combined beams, were simulated using finite-difference time-domain methods. The exposure performance we estimated was verified by temperature elevations of surface in a physical arm-shaped silicone phantom during the MMW exposure. The interference fringes generated in the exposed area due to the combined two-directional beam radiations were observed both in the simulation and in the phantom experiment but eliminated by applying an orthogonalizing polarized feeding structure. Under these exposure conditions, the local temperature changes, which could evoke warmth sensations, were obtained at the target area of the human forearm skin, which means the achievement of exposure performance we intended.

Positive Association Between Location of Melanoma, Ultraviolet Signature, Tumor Mutational Burden, and Response to Anti–PD-1 Therapy

PURPOSE Emerging evidence suggests a correlation between the tumor mutational burden (TMB) and the response to programmed cell death-1 protein (PD-1) monotherapy across multiple cancer types. In skin cancers, as high TMB is mostly because of ultraviolet (UV) exposure, we hypothesized a correlation between the primary melanoma cutaneous location according to sun exposure and response to anti–PD-1 monotherapy. METHODS The aim of this study was to analyze, in advanced melanoma, the relationship between TMB, locations according to sun exposure, and response to PD-1 inhibitors. We conducted a prospective multicentric analysis, by sequencing the most recent metastatic sample before PD-1 inhibitors using FoundationOne assay. RESULTS One hundred two patients were included, with TMB available for 94 cases. In univariate and multivariate linear regression, TMB was significantly associated with sun-exposed areas of the primary melanoma location and with age (coefficients of the association with log-TMB: non-UV location, –1.05; chronic sun-exposed area, 1.12; P value for the location, < 10–5; age, 0.021 per year, P value for age, .002). Molecular UV signature present on the metastatic site was associated with higher TMB ( P = .003). Melanomas bearing a high TMB had a higher probability of response to PD-1 inhibitors compared with melanomas with a low TMB, with a dose-dependent effect following an exponential curve and a negative odds ratio of 0.40 (95% CI, 0.20 to 0.72, P = .004) between log-TMB and 6-month progression. CONCLUSION Cumulative sun exposure related to skin location and molecular UV signature present on the metastatic site appear to be relevant biomarkers directly linked to TMB. Because TMB is not yet available to all for routine clinical use, the location of the primary melanoma in a sun-exposed area may play an important role in clinical decisions regarding therapeutic choice.

What Is a Solitary Keratoacanthoma? A Benign Follicular Neoplasm, Frequently Associated with Squamous Cell Carcinoma

We present histopathological criteria for diagnosing keratoacanthoma (KA). In KA, four histological stages are recognized, which are the early/proliferative stage, well-developed stage, regressing stage and regressed stage. In diagnosing KA, we emphasize that KA consists of the proliferation of enlarged pale pink cells with ground glass-like cytoplasm without nuclear atypia, other than crateriform architecture. KA sometimes exhibits malignant transformation within the lesions. We describe the characteristics of benign and malignant epithelial crateriform tumors that should be differentiated from KA. We also present the data of histopathological diagnosis of lesions clinically diagnosed as KA, its natural course and related lesions after partial biopsy, and incidence of crateriform epithelial neoplasms. Based on these data, we recommend complete excision of the lesion when KA is clinically suspected, especially when the lesion is located on a sun-exposed area of an elderly patient. If complete excision is impossible, partial excision of a sufficient specimen with intact architecture is required. In such a case, however, careful investigation after biopsy will be needed, even if the histopathological diagnosis is KA, because there is some possibility that a conventional SCC lesion remains in the residual tissue.

Could the accident of “Ever Given” have been avoided in the Suez Canal?

The paper analyzes the causes of the accident that took place on March 23, 2021 at 101 kilometers of the Suez Canal with the supercontainer ship “Ever Given”. The vessel lost control at the narrowest point of the transoceanic corridor. According to various sources, the possible cause of the accident was weather conditions. At the moment of passing through the Suez Canal, the vessel got into the area of a sandstorm with the increased wind speed and poor visibility. Sandstorms are frequent in the area. To avoid similar accidents, a quantitative analysis was performed to determine its causes. The analysis was undertaken based on solving the system of equations for mathematical model of a container ship with similar characteristics. The calculation was carried out according to well-proven methods with the involvement of databases for determining the hydrodynamic and aerodynamic characteristics. It has been established that a vessel with wind exposed area typical for vessels of the “Ever Given” type cannot be steered at wind speeds exceeding 12 m/s. In addition, a significant effect of the density of the air-dust mixture on the controllability of the vessel has been found. In the presence of an admixture of sand in the air, the vessel can lose controllability even at 9 m/s.

Assessment of environmental impacts of Rabak cement factory on vegetation and soil by cement dust

Globally, the cement industry has been identified as a factor which causes significant pollution. This study is conducted to assess environmental impacts of cement industry - Rabak Cement Factory on vegetation and soil. Standard methods were followed in collecting, preparation and examination of some plant and soil samples from the study areas. The results showed that, the mean values of soil pH, electric conductivity and moisture contents, were (7.58, 449.38 µs/cm, 4.56%), respectively in the exposed area, and (7.28, 343.63 µs/cm, 4.31%) in the unexposed area. There were significance differences between exposed and unexposed areas with regard to concentrations of oxides of elements (Fe2O3, CaO, MgO, Mn2O, Na2O and K2O) in soil and in different vegetables (Radish, Jews mallow, Fennel, Rocket) in the study area. The factory management should further provide the latest technologies to reduce industrial emissions to protect the environment and population living around the factory. Further studies are needed to investigate the impacts of cement industry on environment.

African Heritage Sites threatened by coastal flooding and erosion as sea-level rise accelerates

Important heritage sites along the African coast are at risk from the threats associated with rising sea levels. Here, we quantify the exposure of natural and cultural heritage sites in Africa to coastal flooding and erosion in the 21st century. We develop a comprehensive database of 284 coastal African Heritage Sites (AHS), composed of 213 natural and 71 cultural heritage sites, which is then combined with coastal flooding and erosion projections to assess exposure to coastal extreme events for a moderate (RCP4.5) and high (RCP8.5) greenhouse gas emissions scenario. We find that 56 AHS are presently at risk from a 100-year extreme sea-level event, with a total exposed heritage area of 2,222 km2. Most of the currently exposed AHS are located in Northern and Western Africa. By mid-century, the number of exposed AHS is projected to increase more than 3 times to reach 191 and 198 under moderate and high emissions respectively. In the second half of the century, the number of exposed sites stabilizes, but the median exposed area increases to 6.6 to 8.5 times the present-day value, under moderate and high emissions, respectively. Mitigation from high to moderate emissions will reduce the end-century median exposed area and number of very highly exposed sites by 20% and 25% respectively.

Optimized Placement of Voltage Sag Monitors Considering Distributed Generation Dominated Grids and Customer Demands

Voltage sag causes serious economic losses to sensitive customers. However, the existing optimal placement methods of sag monitors ignore the economic needs of customers. The optimal placement model of voltage sag monitor is proposed in this paper, which considers the sag economic loss weight, realizes the redundant coverage of important customers, and reduces the risk of sag loss of them. The model is also suitable for the system with a large number of DG access. Firstly, the calculation model of exposed area based on Chebyshev iterative method is established to obtain the system exposed area quickly, and the influence of DG replacing traditional generator on exposed area and economic loss is analyzed qualitatively. Then, the economic loss is quantitatively evaluated based on the exposed area. What’s more, the priority of important customers is determined accordingly, and the optimal placement model of sag monitor is proposed. Finally, simulation results show that in large-scale DG access, the customer’s economic loss caused by sag will increase. Compared with traditional methods, this method can reduce the risk of loss and ensure the economic benefits of important customers.

Fasting increases shelter use in house crickets (Acheta domesticus)

Fasting, i.e. depriving the animals of food prior to harvesting, has been practised in the production of house crickets (Acheta domesticus). However, the effectiveness of this method in reducing microbial loads is still unclear. In addition, there may be costs of fasting to the organism, which could compromise product quality and animal welfare. Here, we analysed spontaneous behaviour displayed after 0, 24 or 48 hours of fasting. We show that after 48 hours of fasting, shelter use was increased and the duration spent on the exposed area of the floor was decreased. The same trend was seen after 24 hours fasting. Moreover, in both fasting treatments, a strong reduction in grooming was seen. We conclude that, in the absence of a microbial lowering effect of fasting and considering the current finding that fasting induces behavioural responses in crickets, there is currently no scientific support for using fasting in cricket production.