scholarly journals TCF7L2 rs290481 T>C polymorphism is associated with an increased risk of type 2 diabetes mellitus and fasting plasma glucose level

Oncotarget ◽  
2017 ◽  
Vol 8 (44) ◽  
pp. 77000-77008 ◽  
Author(s):  
Li Zhu ◽  
Zhiqiang Xie ◽  
Jianping Lu ◽  
Qiu Hao ◽  
Mingqiang Kang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Plasma Glucose Level ◽  
Fasting Plasma Glucose Level ◽  
Increased Risk

The risk of type 2 diabetes mellitus according to 2-h plasma glucose level: The Korean Genome and Epidemiology Study (KoGES)

2018 ◽  
Vol 146 ◽  
pp. 130-137 ◽  
Author(s):  
Sung Keun Park ◽  
Jae-Hong Ryoo ◽  
Chang-Mo Oh ◽  
Joong-Myung Choi ◽  
Young-Jun Choi ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Plasma Glucose Level ◽  
Epidemiology Study

scholarly journals Association of serum creatinine levels and risk of type 2 diabetes mellitus in Korea: a case control study

2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Do Kyeong Song ◽  
Young Sun Hong ◽  
Yeon-Ah Sung ◽  
Hyejin Lee
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Skeletal Muscle ◽  
Type 2 Diabetes Mellitus ◽  
Serum Creatinine ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Increased Risk

Abstract Background Reduced skeletal muscle has been suggested as a potential risk factor for type 2 diabetes mellitus (T2DM). Serum creatinine is the primary metabolite of creatine in skeletal muscle. Therefore, low serum creatinine levels may be associated with an increased risk of T2DM. We aimed to evaluate the association between serum creatinine levels and the risk of T2DM in Korea. Methods We analyzed a total of 264,832 nondiabetic adults older than 40 years of age who had undergone a national health examination at least once from 2009 to 2015 in the Korean National Health Insurance Service Cohort. Hazard ratios for T2DM were calculated. Results In men, serum creatinine levels and the risk for T2DM showed an inverse J-shaped association. This association was confirmed after adjustment for age, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), and fasting plasma glucose. In women, there was a trend that serum creatinine levels were inversely associated with the risk of T2DM among those with serum creatinine below 1.1 mg/dl. However, serum creatinine levels were not significantly associated with the risk of T2DM after adjustment for age, BMI, SBP, DBP, and fasting plasma glucose. Conclusions Reduced levels of serum creatinine were significantly associated with an increased risk of T2DM in men with creatinine below 1.20 mg/dl. There was a trend that decreased levels of serum creatinine were associated with an increased risk of T2DM among women with serum creatinine below 1.1 mg/dl, although this result was not statistically significant.

scholarly journals The Effect of Tempe Dietary Intake on Plasma Glucose Level in Elderly Patients with Type 2 Diabetes Mellitus

2017 ◽  
Vol 1 (6) ◽  
Author(s):  
Grace Puspasari ◽  
Drupadi Dillon ◽  
Budiman Budiman
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Treatment Group ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Plasma Glucose Level ◽  
Daily Intake ◽  
Control Group

The aim of the study was to investigate  the effect of daily intake of 100 grams tempe for four weeks on plasma glucose level in elderly patients with type 2 diabetes mellitus. This study was a parallel randomized clinical trial. Subjects were 30 diabetic elderly living in four nursing homes in Jakarta. In the study subjects were assigned to two groups using block randomization. All subjects had to take diabetic regiment with calorie and macronutrient following diabetic recommendation diet. The treatment group (n=16) received tempe, while control group (n=14) received legumes other than tempe. Fasting plasma glucose level (FPG) was assessed before and after intervention. Unpaired t test and Mann Whitney were used to analyzed data with the 5% significance level. There were 27 subjects completed the study: 15 of treatment group and 12 of control group. Both group were comparable in age, gender, BMI, calorie and macronutrient intake before treatment. Fat, fiber, and isoflavone intake were significantly higher in treatment group compare to control group. Decrease in FPG after intervention were observed but were statisticaly insignificant. In conclusion daily intake of 100 grams tempe for four weeks did not decrease FPG.  Keywords: elderly, plasma glucose level, tempe, type 2 diabetes

scholarly journals HIGH BLOOD GLUCOSE LEVEL INCREASE CARDIOVASCULAR DISEASE RISK IN TYPE 2 DIABETES MELLITUS

2017 ◽  
Vol 52 (2) ◽  
pp. 127
Author(s):  
Laili Zahrina Marchelia ◽  
Purwati Purwati ◽  
Rio Wironegoro
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Cardiovascular Disease ◽  
Type 2 Diabetes Mellitus ◽  
Glucose Level ◽  
Plasma Glucose ◽  
Fasting Plasma Glucose ◽  
Postprandial Glucose ◽  
Type 2 Dm

Type 2 diabetes mellitus (DM) is the 10th leading cause of death in the world and had a risk 4.06 times greater to have cardiovascular disease (CVD). Fasting plasma glucose and 2-hours postprandial glucose level as diagnostic tests to evaluate DM and also as a predictive factors to CVD. This research uses descriptive analytic research with cross sectional design. The subject of this study is Type 2 DM patients came to Dr Soetomo hospital from January-October 2014. Data was recorded from medical records of patients and was analyzed with Chi Square test with p<0.05. As result, there is 102 Type 2 DM patients with 36 patients have CVD manifestation and 66 patients without complication. There is a significant association between fasting plasma glucose (FPG), 2-hours postprandial glucose (2hPPG) level, and CVD manifestation (p=0.00). So FPG and 2hPPG have a significant association with CVD manifestation. There are other factors that influencing the formation of CVD, hence, further research is needed.

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