scholarly journals Lumbago is different from prolapse of lumbar intervertebral disc

2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Wei Zhou ◽  
Yanbo Qiu ◽  
Shaoqiu Zhou ◽  
Wei Zhao
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Lumbar Disc ◽  
Posterior Longitudinal Ligament ◽  
Low Back ◽  
Lumbar Intervertebral Disc ◽  
Disc Protrusion ◽  
Medical Reform ◽  
System Disease

<p>There are many errors found in the content of textbook in National Higher Education.For example:One of the errors found in the“Surgery”version no 418 is about movement system disease section.In chapter 677 Section III,the content misinterpretation of the cause of low back pain is the intervertebral disc protrusion that stimulate the outer annulus and the posterior longitudinal ligament in the sinus nerve fibers.For the past twenty years,feedbacks had been reflected repeatedly to the involved party but no one had admitted the contents of the textbook are wrong.The errors had brought great economy loss,physical and mental pain to patients.Every year,the country has to spend billions of dollars in the waste of medical reform reimbursement.This article is aimed to discuss about low back pain is not due to lumbar disc herniation.</p>

Does elite swimming accelerate lumbar intervertebral disc degeneration and increase low back pain? A cross-sectional comparison

2016 ◽  
Vol 25 (9) ◽  
pp. 2849-2855 ◽  
Author(s):  
Steffen Folkvardsen ◽  
Erland Magnussen ◽  
Jaro Karppinen ◽  
Juha Auvinen ◽  
Rasmus Hertzum Larsen ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Intervertebral Disc Degeneration ◽  
Low Back ◽  
Lumbar Intervertebral Disc ◽  
Cross Sectional

scholarly journals Transforaminal Epidural Injection of Dexamethasone vs Methylprednisolone in Reducing Low Back Pain and Disability in Prolapsed Lumbar Intervertebral Disc in Manipur, India: A RCT

2021 ◽  
Author(s):  
Kanti Rajkumari ◽  
Akoijam Joy Singh ◽  
Longjam Nilachandra Singh ◽  
Margaret Chabungbam ◽  
C Sreejith ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Steroid Injection ◽  
Epidural Injection ◽  
P Value ◽  
Low Back ◽  
Lumbar Intervertebral Disc ◽  
Transforaminal Epidural Injection ◽  
Epidural Steroid

Introduction: Treatment for Low Back Pain (LBP) due to Prolapsed Intervertebral Disc (PIVD) includes conservative management, Epidural Steroid Injection (ESI), and surgery. Transforaminal Epidural Steroid Injection (TFESI) is a more recently described approach. All corticosteroid preparations used for TFESI are particulate except dexamethasone and betamethasone sodium phosphate. But while comparing methylprednisolone with dexamethasone, the latter has more potent anti-inflammatory action with least likelihood of causing embolic events and is also less expensive. Aim: To compare the efficacy of transforaminal epidural injection of dexamethasone and methylprednisolone in reducing LBP and disability in prolapsed lumbar intervertebral disc amongst the indigenous population of Manipur, India. Materials and Methods: This was a randomised controlled study on 80 patients with PIVD attending Outpatient Department (OPD) at physical medicine and rehabilitation was conducted from September 2016 to August 2018. A single dose of lumbar TFESI with dexamethasone in the study group and methylprednisolone in the control were given under C-arm guidance. The outcome variables Visual Analog Scale (VAS) for pain and Oswestry Disability Index (ODI) for function were measured at one week, one month and six months. Statistical tests like t-test, Chi-square test were used for intra group and inter group analysis. Results: In the total sample of 80 patients, 40 (15 males and 25 females, mean age: 38.28±8.55 years) were categorised as Dexamethasone patients and 40 (17 males and 23 females; mean age: 39.28±7.80 years) as methylprednisolone patients, there were significant improvement in mean score of VAS and ODI in both the groups (p-value <0.05). At six months, both treatment groups maintained initial observed improvements, with no significant differences between groups on the VAS {95% Confidence Interval (CI), -0.02 to 0.4; p-value=0.07} and ODI (95% CI,-0.21 to 3.43; p-value=0.08). Conclusion: Non-particulate steroid dexamethasone was similar in efficacy to the particulate steroid methylprednisolone in lumbar TFESI. However, in view of the greater safety profile of dexamethasone, it is suggested that dexamethasone may be used as the preferred agent in lumbar TFESI.

scholarly journals Establishment of a New Model of Lumbar Intervertebral Disc Degeneration With Pathological Characteristics

2021 ◽  
pp. 219256822110123
Author(s):  
Yongming Jin ◽  
Guangfeng Mao ◽  
Chen Yang ◽  
Chen Xia ◽  
Chuyong Chen ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Disc Degeneration ◽  
Lumbar Disc ◽  
Enzyme Linked Immunosorbent Assay ◽  
Low Back ◽  
Lumbar Disc Degeneration ◽  
Discogenic Low Back Pain ◽  
Collagen Ii

Study Design: A prospective study. Objectives: Intervertebral disc degenerative disease is a common and frequently-occurring disease in adults and is the main cause of lower back pain. However, there is a lack of universal animal models to study disc degeneration. Methods: Forty-two male New Zealand white rabbits aged 12 months were used in this study. We established an endplate ischemic disc degeneration model though surgical ligation of rabbit lumbar vertebral body segment arteries. Two weeks after surgery, 6 experimental animals were randomly selected for follow-up tests. First, ischemia and lumbar disc degeneration were confirmed using imaging techniques. Then, immunohistochemical staining was performed to observe the growth of the annulus fibrosus. Finally, quantitative polymerase chain reaction, enzyme-linked immunosorbent assay, and western blotting were used to detect mRNA expression and protein content of IL-1α, TNFα, collagen II, MMP-3, aggrecan, and PLA2 in the nucleus pulposus of the disc. Results: Imaging examination confirmed the successful construction of a lumbar disc degeneration model. Histological analysis and biochemical analysis showed a damaged intervertebral disc structure, and collagen II and aggrecan, the key extracellular matrix components of intervertebral discs, were reduced in synthesis and content. The synthesis and expression of IL-1α, TNFα, PLA2, and MMP-3 related to disc catabolism and inflammatory response were enhanced. Conclusions: We successfully constructed a lumbar disc degeneration ischemia model, which provides a novel approach to study the pathological mechanisms involved in discogenic low back pain and to prevent and treat discogenic low back pain.

scholarly journals Epidemiology of lumbar disc herniations in adults with low back pain in Enugu, Nigeria

2019 ◽  
Vol 6 (1) ◽  
pp. 1
Author(s):  
Godson E. Anyanwu ◽  
Remigius T. Ekwunife ◽  
Emmanuel C. Iyidobi ◽  
Cajetan U. Nwadinigwe ◽  
Henry C. Ekwedigwe ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Lumbar Disc Herniation ◽  
Disc Herniation ◽  
Lumbar Disc ◽  
Low Back ◽  
Inclusion Criteria ◽  
Laptop Computer ◽  
Disc Herniations

<p class="abstract"><strong>Background:</strong> Lumbar intervertebral disc herniation is used to describe a spectrum of anatomical abnormalities involving disc extension beyond the interspace. It follows a tear in the annulus fibrosus of the intervertebral disc. It is one of the most common causes of low back pain among adults. The study aims to assess the epidemiological pattern of lumbar disc herniations among adults with low back pain in Enugu urban.</p><p class="abstract"><strong>Methods:</strong> The study was a prospective study at National Orthopedic Hospital Enugu and Annunciation Specialist Hospital Enugu. Following ethical approval and written informed consent, patients who met the inclusion criteria were consecutively recruited. The MRI scans of the participants were viewed using DICOM® (Digital Imaging and Communications in Medicine) software on laptop computer. The data included the patients’ demographics, functional disability index for back pain, weight, height, the anatomical level(s) and site(s) of the herniated disc among other parameters.<strong></strong></p><p class="abstract"><strong>Results:</strong> A total of 81 subjects who met the inclusion criteria were included and analyzed using SPSS version 20.0. The mean age of the subjects is 52.99±13.13 years. The most common affected age group is 51-60 years (27.2%). Majority of the subjects (68; 84%) had multiple level herniations which usually includes L4 level(74; 91.4%).</p><p class="abstract"><strong>Conclusions:</strong> That multilevel lumbar disc herniation is far more common than single level herniation with a prevalence of 84% among adults with low back pain in Enugu urban. That, there is statistically significant association of lumbar disc herniation and increasing age.</p>

scholarly journals SubclinicalPropionibacterium acnesinfection estimation in the intervertebral disc (SPInE-ID): protocol for a prospective cohort

BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e017930 ◽  
Author(s):  
Nelson Astur ◽  
Delio E Martins ◽  
Marcelo Wajchenberg ◽  
Mario Ferretti ◽  
Fernando G Menezes ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Prospective Cohort ◽  
Lumbar Disc ◽  
Herniated Disc ◽  
Decompression Surgery ◽  
Low Back ◽  
Informed Consent Form ◽  
Study Results

IntroductionLow back pain and vertebral endplate abnormalities are common conditions within the population. Subclinical infection caused by indolent pathogens can potentially lead to these findings, with differentiation between them notably challenging from a clinical perspective. Progressive infection of the intervertebral disc has been extensively associated with increasing low back pain, withPropionibacterium acnesspecifically implicated with in relation to sciatica. The main purpose of this study is to identify if the presence of an infective pathogen within the intervertebral disc is primary or is a result of intraoperative contamination, and whether this correlates to low back pain.Methods and analysisAn open prospective cohort study will be performed. Subjects included within the study will be between the ages of 18 and 65 years and have a diagnosis of lumbar disc herniation requiring open decompression surgery. Excised herniated disc fragments, muscle and ligamentum flavum samples will be collected during surgery and sent to microbiology for tissue culture and pathogen identification. Score questionnaires for pain, functionality and quality of life will be given preoperatively and at 1, 3, 6 and 12 months postoperatively. A MRI will be performed 12 months after surgery for analysis of Modic changes and baseline comparison. The primary endpoint is the rate of disc infection in patients with symptomatic degenerative disc disease. The secondary endpoints will be performance scores, Modic incidence and volume.Ethics and disseminationThis study was approved by our Institutional Review Board and was only initiated after it (CAAE 65102617.2.0000.0071). Patients agreeing to participate will sign an informed consent form before entering the study. Results will be published in a peer reviewed medical journal irrespective of study findings. If shown to be the case, this would have profound effects on the way physicians treat chronic low back pain, even impacting health costs.Trials registration numberNCT0315876; Pre-results.

Quantitative T2 evaluation at 3.0T compared to morphological grading of the lumbar intervertebral disc: A standardized evaluation approach in patients with low back pain

2012 ◽  
Vol 81 (2) ◽  
pp. 324-330 ◽  
Author(s):  
David Stelzeneder ◽  
Goetz Hannes Welsch ◽  
Balázs Krisztián Kovács ◽  
Sabine Goed ◽  
Tatjana Paternostro-Sluga ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Intervertebral Disc ◽  
Low Back ◽  
Lumbar Intervertebral Disc ◽  
Evaluation Approach
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