scholarly journals Identification of occupational risk for arterial hypertension. 1: elimination of the modifyng influence of factors of cardiovascular risk

2019 ◽  
Vol 95 (3) ◽  
pp. 262-266
Author(s):  
Sergey A. Maksimov ◽  
A. P. Mikhailuts ◽  
G. V. Artamonova

On results of research in 13 occupational groups (3842 workers, men) there were performed an analysis of a contribution of non-occupational factors of cardiovascular risk (FCVRs) and the elimination of their modifying influence on risks for the development of the arterial hypertension (AH). In the capacity of non-occupational FCVRs there were considered 16 predictors of AH. There were calculated the relative risk of AH and 95% the confidential interval (CI) in occupational groups on benchmark data of the prevalence rate of AH and after the elimination of the modifying influence of FCVRs. Reference group was the general sample, that is, all the occupations. Modifying influence of FCVR was eliminated by means of direct standardization. With the aid of trees of classification from the number of FCVRs in occupational groups the presence of obesity and age of the worker (respectively, 100 and 78 conditional points) was shown to have the maximum impact on the development of AH. Elimination of the influence of data of FCVRs led to the change of benchmark values of occupational risks of AH in the average for 10%, in four occupations level of the statistical importance of risks of AH changed. In top-managers, and also in operating personnel and technical workers the risk for AH from the high decreased to not significant, respectively to 1,00 at 95%, CI: 0,74-1,36 and 1,20 at 95%, CI: 0,97-1,49. On the contrary, the risk for AH increased from low to statistically not significant in underground equipment operators (0,85 at 95%, CI: 0,71-1,01) and labourers (0,89 at 95%, CI:0,69-1,14).

2019 ◽  
Vol 95 (4) ◽  
pp. 365-369
Author(s):  
Sergey A. Maksimov ◽  
A. E. Skripchenko ◽  
A. P. Mikhailuts ◽  
G. V. Artamonova

This study is a continuation of (Report I) identification of the occupational risk of arterial hypertension (AH) in 13 occupational groups (3842 workers, men). In previous work there was eliminated the influence of traditional factors of the cardiovascular risk, in this study there was implemented the identification of the components of a healthy worker effect (HWE) and the elimination of their influence on the occupational risks of hypertension. Identification and removal of components HWE - the effect of a healthy recruitment (EHR) and the effect of the healthy worker persisting to work (EHWPW) - was carried out by the analytic rearranging of the standardized for age and obesity prevalence rate of arterial hypertension with the use of own methodological approaches. For the determination of the presence and severity of EHR there was performed an analysis of the initial prevalence rate of arterial hypertension in the youngest age groups (under 31 years). To overcome HER standardized for age and obesity indices of the arterial hypertension prevalence rate were adjusted by the ratio of the frequency of arterial hypertension in the most young occupational and reference comparable groups. Identification ofHWPW was executed by comparing the frequency of AH among workers retiring within 3 years from the occupational groups when compared to the whole sample. Then on the additional risk value there was adjusted the overall prevalence rate of AH in the occupation profession to overcome EHWPW. As a result of the consistent correction and elimination of the influence ofHWE components on the prevalence rate of AH, there were obtained risks values, primarily reflecting the impact of occupational factors which can be considered as true occupational risks. Factors of the cardiovascular risk and HWE significantly modified true occupational risks for AH in a number of occupational groups up to inversion. At the same time, the pronouncement of EHR has a paramount importance in the modifying effect


2012 ◽  
Vol 67 (12) ◽  
pp. 54-59 ◽  
Author(s):  
S. A. Maximov ◽  
A. E. Skripchenko ◽  
G. V. Artamonova

Risk analysis of development of arterial hypertension in 14 occupational groups of Western Siberia (4472 workers) is carried out. As a reference group the all-Russian data on prevalence of arterial hypertension by results of the second stage of monitoring of an epidemiological situation on arterial hypertension in the Russian Federation (2005–2007) were used. Paid off the odds ratio and 95% a confidential interval. The obtained data allowed to characterize occupational distinctions of risk of development of arterial hypertension and to allocate occupational groups of Western Siberia with high level of arterial hypertension. Results of research testifies to need of consideration of healthy worker effect as the factor of formation of frequency of arterial hypertension connected with a profession in occupational groups. 


Author(s):  
T. Yu. Obukhova ◽  
V. B. Gurvich ◽  
L. N. Budkar’ ◽  
S. L. Ust’yantsev ◽  
S. I. Solodushkin ◽  
...  

Relevance. Occupational factor nowadays is considered an important condition of cardiovascular risk increase, including arterial hypertension growth. With this, study of work conditions infl uence on probable arterial hypertension development and other cardiovascular risk factors appears topical.Objective. To construct prognostic model of probable arterial hypertension development in workers of asbestos-concentrating plant, who are exposed to higher concentration of fi brogenic dust containing chrysotile.Materials and methods. Main group (161 individuals) comprised patients with diagnosed occupational disease (asbestosis), reference group included workers (222 individuals) with long length of service, without occupational diseases. Th e groups matched in age, sex, length of exposure to hazards, smoking index.Results. Findings are high occupational conditionality of left  ventricle hypertrophy (relative risk 3.217, att ributable fraction 54.32%). Revealed factors that promote occupationally conditioned arterial hypertension (asbestosis, obesity, increased serum glucose, coronary heart disease, increased heart rate, lower saturation) served as a basis for prognostic model design by logic regression.Conclusion. Mathematic modelling helps to define contribution of occupational and non-occupational factors into arterial hypertension development in workers exposed to fi brogenic dust. Dust factor is an additional risk factor in arterial hypertension development am ong workers engaged into asbestos-concentrating production. 


Nanoscale ◽  
2017 ◽  
Vol 9 (39) ◽  
pp. 14897-14906 ◽  
Author(s):  
Ana F. Guedes ◽  
Filomena A. Carvalho ◽  
Carlos Moreira ◽  
José B. Nogueira ◽  
Nuno C. Santos

Arterial hypertension patients present stronger erythrocyte–erythrocyte interactions and high levels of γ′ fibrinogen, which compromise microcirculation and increase the cardiovascular risk.


2020 ◽  
Vol 12 (14) ◽  
pp. 68-72
Author(s):  
Ruziyeva Amira Asrorovna ◽  
Muradova Railya Rustamovna ◽  
Turaev Khikmatulla Negmatovich ◽  
Nuralieva Rano Matyakubovna

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