Asymptomatic Bacteriuria and Urinary Tract Infection in Pregnancy

Author(s):  
Mary Lee Barron ◽  
Kelly D. Rosenberger ◽  
Amy M. Seibert
Author(s):  
Ashish Khanna ◽  
Menka Khanna

<strong>Background:</strong>Bacteriuria during pregnancy has been known to cause many complications like low birth weight and premature delivery.<p><strong>Objective</strong>: This study was done to evaluate the diagnostic accuracy of rapid dipstick test to predict urinary tract infection in pregnancy against the gold standard urine culture.</p><p><strong>Material&amp;Methods:</strong> A total of 200 mid stream urine samples were collected from asymptomatic pregnant females. These specimens were cultured in blood agar and MacConkey's agar by using the standard loop technique and incubated aerobically at 37°C overnight. The criterion for clinically significant bacteriuria was either a pure or predominant culture of &gt;10<sup>5</sup> colony forming units (CFU)/ml. All the specimens were also examined microscopically for pyuria and bacteriuria.</p><p><strong>Results:</strong> The prevalence of asymptomatic bacteriuria in pregnancy was 15 % in our study. The sensitivity and the specificity for leucocyte esterase were 85.7% and 74.4% and for nitrites, they were 64.2% and 72%.</p><p><strong>Conclusion:</strong> The study revealed that use of either leukocyte esterase or nitrite for screening of asymptomatic bacteriuria in pregnancy was associated with many false positive and negative results when compared with the gold standard urine culture method. By using their combination maximum negative predictive value of .98 was achieved.</p>


2010 ◽  
pp. 2103-2107
Author(s):  
John D. Firth

Urinary tract infection—2 to 10% of pregnancies are complicated by asymptomatic bacteriuria, which progresses to symptomatic infection in 40% of cases and is associated with adverse fetal outcome. Antibiotic treatment reduces the chances of developing symptomatic infection and of infants being born with low birth weight....


2018 ◽  
Vol 11 (1) ◽  
pp. 19
Author(s):  
Edy Fakhrizal

To obtain a prevalence of urinary tract infection in pregnancy andits influential risk factors.This is a cross sectionalstudy. The subjects were all pregnant women who came to Obstetric & Gynecology clinic of Arifin Achmad Pekanbaru– Riau Hospital, between June 1st and October 31st 2016. Subjects with appropriate inclusion and exclusion criteriaand agreed to join this study were asked to fill out questionnaire and urinalysis test was done.The data was analyzedwith Stata 12. The distribution of data was analyzed with descriptive univariate and presented in (n) and(%). Bivariateanalysis was done to see any influential risk factors to urinary tract infection in pregnancy. From recruited 74 subjects,27subjects (36,5%) were with urinary tract infection and 4 subject of its (14,8%) was asymptomatic bacteriuria. Theprevalence of urinary tract infection in pregnancy in this study was 36,5% and the influential risk factors wereeducation, occupation, total water consumpted a day, and cleaning vagina before coitus.


1994 ◽  
Vol 28 (2) ◽  
pp. 248-251 ◽  
Author(s):  
Lavern M. Vercaigne ◽  
George G. Zhanel

OBJECTIVE: To establish and recommend a therapeutic regimen for the treatment of urinary tract infection (UTI) in pregnancy based on the published studies. DATA SOURCES: An English-language literature search employing MEDLINE, Index Medicus, and bibliographic reviews of the references obtained were searched (key terms: urinary tract infection, UTI, pregnancy, bacteriuria). STUDY SELECTION AND DATA EXTRACTION: All identified human studies dealing with bacteriuria or UTI in pregnancy were analyzed. DATA SYNTHFSIS: Limited data are available regarding the appropriate antibiotic management of UTI in pregnancy. Single-dose cure rates with amoxicillin are approximately 80 percent. Trimethoprim/sulfamethoxazole provides cure rates of greater than 80 percent. Cephalosporins and nitrofurantoin produce variable results. CONCLUSIONS: We recommend separating pregnant subjects with UTI into two groups. Those with asymptomatic bacteriuria can be treated with a single dose of an antimicrobial to which the organism is susceptible. For those with symptomatic UTI, we recommend amoxicillin 500 mg tid for three days. Urine cultures should be repeated seven days following therapy to assess cure or failure. Well-designed studies need to be performed, comparing single-dose and three-day therapy for UTI in pregnancy.


Author(s):  
Indira Guntoory ◽  
Poornima Penmetsa ◽  
Sarath B. Rayapu ◽  
Nambaru R. Nambaru

Background: Urinary tract infection in pregnancy is a problem of global significance. Untreated asymptomatic bacteriuria in pregnancy is known to be associated with maternal and foetal outcome in the form of symptomatic urinary tract infection (UTI), acute pyelonephritis, anaemia, pregnancy induced hypertension (PIH), preterm labour (PTL), low birth weight (LBW), intrauterine growth restriction (IUGR) and prematurity. This study is aimed to compare the maternal and foetal outcome of pregnant women with bacteriuria with that of women without bacteriuria and also to see if screening later in pregnancy at 28-37 weeks of gestation is as effective as screening at less than 20 weeks of pregnancy in terms of maternofoetal outcome.Methods: 165 pregnant women attending the antenatal clinic at MIMS, Nellimerla, Vizianagaram district, Andhra Pradesh, India were screened for asymptomatic bacteriuria by urine culture and sensitivity. They were grouped into asymptomatic bacteriuria negative and culture positive groups. Culture positives were further grouped as early detected and late detected group based on the gestational age at sampling. They were followed up till delivery. The maternofoetal outcome was compared between different groups by computing Odd’s ratio and P value of less than 0.05 was taken as significant.Results: There was no statistically significant increase in adverse maternofoetal outcome between early detected and bacteriuria negative group. The women of late detected group had greater odds of developing symptomatic UTI, PIH, PTL, LBW, IUGR and neonatal intensive care unit admissions when compared to early detected and bacteriuria negative group which was statistically significant.Conclusions: Screening for asymptomatic bacteriuria early in pregnancy at less than 20 weeks is more effective in reducing the adverse maternofoetal outcome.


Author(s):  
Nalam Neelima ◽  
Ushadevi Gopalan

Asymptomatic bacteriuria is more common in pregnancy and if left untreated it may progress to upper urinary tract infection. Early detection and treatment of asymptomatic bacteriuria prevents further progression of the infection and thereby preventing undesirable complications to the mother and fetus. It is advisable to do Urine culture and sensitivity in all antenatal women irrespective of the gestational age and symptoms.


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