scholarly journals In-Vitro cytotoxicity activity of Mallotus oppositifolius and Enantia polycarpa extracts against Human Foreskin Fibroblast (HFF) Cell Line

2016 ◽  
Vol 12 (6) ◽  
pp. 29
Author(s):  
Alain S.A. Ambe ◽  
Cynthia Y. Yapo ◽  
Bosson A.M.B. Orsot ◽  
Goueh Gnahoue ◽  
Djeneb Camara ◽  
...  

The use of plants in traditional medicine become very common nowadays throughout the world and in developing countries in particular. The current study was carried out aiming to evaluate the cytotoxicity of Mallotus oppositifolius (Geisel.) Müll.-Arg (Euphorbiaceae) and Enantia polycarpa (DC) Engl. and Diels (Annonaceae) two medicinal plants mostly used for human traditional medicine to treat diarrhea in Côte d’Ivoire on Human Foreskin Fibroblast (HFF) cells. These plants were selected after ethno-botanical investigations in southern Côte d’Ivoire. Therefore, The results proved that the ethanolic extract of Enantia polycarpa showed the biggest yield (56,4%). The 70 % éthanolic extract of Mallotus oppositifolius is not cytotoxic at 1000 µg / ml concentration, but mitogen. Our study has shown that the ethanolic extract of Mallotus oppositifolius stimulates HFF cells (131% of viability confluents cells and 156% of viability cells in division). While Enantia polycarpa seems cytotoxic on HFF cells at 1000 µg / ml concentration (36% of viability confluents cells and 55% of viability cells in division). The study revealed that the moderate use of these medicinal plants only represents a limited risk of toxicity.

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
Bruno Koffi Koko ◽  
Brou André Konan ◽  
Jules Marius Kacou Djetouan ◽  
Flora Kouamé Amoin Kouacou ◽  
Jeanne Akoua Kanga ◽  
...  

<p>This study aims to inventory plants and traditional medicinal recipes used by the population of Tanda (Gontougo region, Côte d’Ivoire) to boost milk production in women.</p><p>Using a questionnaire, the methods consisted in carrying out a survey near the traditional medicine actors of 15 localities. Among 47 actors of traditional medicine aged from 34 to 80 years investigated, 70.21 % were women. These women had more knowledge on the galactagogue plants than the men (29.79 % of the actors). They were represented by matrons, specialists in lactation, healers and saleswomen of medicinal plants. Among about fifteen listed galactagogue plants, <em>Euphorbia hirta </em>(Euphorbiaceae) was the most used plant. Leaves represented the majority of the medicinal preparations (73.33 %). These preparations were in 66.67 % of the cases associated with various other biological or mineral ingredients (pepper, meat, vegetables, ash, kaolin…). The direct application of crushings on mammary glands (cutaneous way) by friction constituted the principal route of administration (66.67 % of the medical receipts).</p>Traditional medicine actors of the town of Tanda are actively interested in the search of solutions to the lacteal secretion issues which occur in the breast-feeding mothers. They have about fifteen medicinal plants which enable them to stimulate the production of maternal milk when a need is expressed.


2004 ◽  
Vol 93 (1) ◽  
pp. 43-49 ◽  
Author(s):  
W.M Koné ◽  
K.Kamanzi Atindehou ◽  
C Terreaux ◽  
K Hostettmann ◽  
D Traoré ◽  
...  

Author(s):  
Koffi Akissi Jeanne ◽  
Tano Konan Dominique ◽  
Kangah Orphée Michelle Alerte ◽  
Rasmane Na Ahou Kaddy ◽  
Ehoulé Kroa ◽  
...  

Mosquitoes have developed resistance, hence the need for anti-malarial medicines. This resistance calls for therapeutic an interest to therapeutic alternatives, including the medicinal plants. An ethnopharmacological survey was conducted amongst 15 Traditional Healers, recommended by the National Program for the Promotion of Traditional Medicine using semi-structured interviews in the city of Bouna. The ethnobotanical survey conducted in 2019 has enabled the identification of 32 plant species belonging to 30 genera and grouped into 19 families. The most represented families were Fabaceae (5 species) Anacardiaceae (4 species), Annonaceae (3 species), Rubiaceae, Zingiberaceae, Asteraceae, and Combretaceae with 2 species each. The species were mostly trees (63.63%). Leaves were the most frequently used parts of the plants (44.4%). The results of our investigations show that the most used mode is the decoction (42.22%). The oral route (60%) is the most used mode of administration. These species complete the non-exhaustive list of medicinal plants that the populations of Cote d'Ivoire use. It was found out that, people in this area commonly use medicinal plants with trust they have built on the curative outcome witnessed. However, this creates a further work to test for the antiplasmodial activity and to develop of Traditional Improved Medicines (MTAs).


2005 ◽  
Vol 43 (1) ◽  
pp. 72-78 ◽  
Author(s):  
W. Mamidou Koné ◽  
K. Kamanzi Atindehou ◽  
Traoré Dossahoua ◽  
Bruno Betschart

2017 ◽  
Vol 13 (12) ◽  
pp. 70
Author(s):  
Kandé Brahima ◽  
Koné Mamidou Witabouna

Pyrrolizidine Alkaloids (PAs) are toxic for human and livestock. Several outbreaks in human intoxications were reported worldwide. This study aimed at assessing the presence and quantifying the PAs in some Asteraceae, Boraginaceae and Leguminosae used in traditional medicine in Côte d'Ivoire. TLC detection with Ehrlich reagent (method of Mattocks) and spectrophotometric dosage were used to analyze 21 plants species. All the studied plants showed at least trace amount of PAs except Caesalpinia bonduc, Parkia filicoidea and Pilostigma thonningii. The contents obtained ranged between 0.261 and 1.518 mg/ml. However, for the majority of the studied plant species, there was a significant difference between aqueous and methanol extracts. The richest species were Heliotropium indicum, Tridax procumbens and Vernonia colorata. The presence of PAs in the studied plants is an indication of people exposure to probable toxicity. This raises the need for an evaluation of the risk related to the consumption of such medicinal plants in Côte d'Ivoire.


2021 ◽  
Vol 15 (3) ◽  
pp. 1104-1120
Author(s):  
Serge-Roland Sidio ◽  
Koffi N'guessan

Dans le but de contribuer à la sauvegarde des savoirs médicaux ancestraux et à la valorisation de la médecine traditionnelle, cent vingt tradipraticiens du département de Gagnoa ont été soumis à des entretiens semi-structurés portant sur les procédés nomenclaturaux des plantes médicinales employées dans le traitement des troubles gastroentérologiques. Ainsi, cinquante et une plantes médicinales ont été inventoriées et reparties en 47 genres et 24 familles d’Angiospermes avec une prépondérance des Fabaceae et des Lamiaceae regroupant chacune 13,73% des espèces recensées. Ces plantes portent des appellations en langues locales ivoiriennes. Quarante-cinq espèces portent des noms en langue autochtone Bété représentant 88,24% des espèces recensées. Seulement neuf d’entre elles sont désignées par des noms ayant un sens. Leurs significations se rapportent soit à leur milieu de vie, soit à leur utilité ou à leur aspect ou encore font référence à des animaux. Cette étude revêt un intérêt pour les pays africains, en particulier la Côte d’Ivoire où le savoir ancestral se perd au fil du temps avec l’abandon d’un certain nombre de valeurs culturelles.   order to contribute to the preservation of ancestral medical knowledge and the promotion of traditional medicine, one hundred and twenty tradipraticians of the department of Gagnoa were subjected to semantic interviews structured on the nomenclatural processes of medicinal plants used in the treatment of gastroenterological disorders. Thus, fifty-one medicinal plants were inventoried and divided into 47 genera and 24 families of Angiosperms with a preponderance of Fabaceae and Lamiaceae, each comprising 13.73% of the species surveyed. These plants have names in local Ivorian languages. Forty-five species have native Bété names representing 88.24% of the species surveyed. Only nine are referred to as names with meaning. Their meanings refer either to their environment, their usefulness or their appearance, or to animals. This study is of interest to African countries, in particular Côte d'Ivoire, where traditional knowledge is lost over time with the abandonment of certain cultural values


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