Impact of Socio-Economic Status, Rural Background and Gender on the Prevalence of Chronic Obstructive Pulmonary Disease

2016 ◽  
Vol 5 (2) ◽  
pp. 1247
Author(s):  
A. Vardhan
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Economic Status ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Rural Background ◽  
Socio Economic Status ◽  
And Gender

scholarly journals LINC01414/LINC00824 genetic polymorphisms in association with the susceptibility of chronic obstructive pulmonary disease

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xiaoman Zhou ◽  
Yunjun Zhang ◽  
Yutian Zhang ◽  
Quanni Li ◽  
Mei Lin ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Genetic Polymorphisms ◽  
Chronic Obstructive ◽  
Nucleotide Polymorphisms ◽  
Obstructive Pulmonary Disease ◽  
Logistic Analysis ◽  
Copd Patients ◽  
Increased Risk ◽  
And Gender

Abstract Objective Chronic obstructive pulmonary disease (COPD) is a complicated multi-factor, multi-gene disease. Here, we aimed to assess the association of genetic polymorphisms in LINC01414/ LINC00824 and interactions with COPD susceptibility. Methods Three single nucleotide polymorphisms (SNPs) in LINC01414/LINC00824 was genotyped by Agena MassARRAY platform among 315 COPD patients and 314 controls. Logistic analysis adjusted by age and gender were applied to estimate the genetic contribution of selected SNPs to COPD susceptibility. Results LINC01414 rs699467 (OR = 0.73, 95% CI 0.56–0.94, p = 0.015) and LINC00824 rs7815944 (OR = 0.56, 95% CI 0.31–0.99, p = 0.046) might be protective factors for COPD occurrence, while LINC01414 rs298207 (OR = 2.88, 95% CI 1.31–6.31, p = 0.008) risk-allele was related to the increased risk of COPD in the whole population. Rs7815944 was associated with the reduced risk of COPD in the subjects aged > 70 years (OR = 0.29, p = 0.005). Rs6994670 (OR = 0.57, p = 0.007) contribute to a reduced COPD risk, while rs298207 (OR = 7.94, p = 0.009) was related to a higher susceptibility to COPD at age ≤ 70 years. Rs298207 (OR = 2.54, p = 0.043) and rs7815944 (OR = 0.43, p = 0.028) variants was associated COPD risk among males. Rs7815944 (OR = 0.16, p = 0.031) was related to the reduced susceptibility of COPD in former smokers. Moreover, the association between rs298207 genotype and COPD patients with dyspnea was found (OR = 0.50, p = 0.016), and rs7815944 was related to COPD patients with wheezing (OR = 0.22, p = 0.008). Conclusion Our finding provided further insights into LINC01414/LINC00824 polymorphisms at risk of COPD occurrence and accumulated evidence for the genetic susceptibility of COPD.

scholarly journals Illness perception in chronic obstructive pulmonary disease

2010 ◽  
Vol 63 (3-4) ◽  
pp. 179-182 ◽  
Author(s):  
Marija Mitkovic ◽  
Lidija Ristic ◽  
Olivera Zikic ◽  
Vuk Milosevic ◽  
Grozdanko Grbesa
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Economic Status ◽  
Family Relations ◽  
Illness Perception ◽  
Personal Control ◽  
Self Report ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Copd Patients

Introduction The aim of the study was to investigate illness perception in patients with chronic obstructive pulmonary disease (COPD), and to explore its relation to socio-demographic and illness/treatment-related characteristics. Material and methods 44 consecutive COPD patients answered the general questionnaire (which identified data on gender, age, education, economic status, employment, personal estimate of family relations quality) and IPQ-R (which evaluates the illness perception components). The data were statistically processed using T-test, Mann-Whitney U-test, one way anova, and correlation analysis. Results COPD patients perceived their illness predominantely negatively. The markers of negative illness perception were female gender, older age, medium economic status, being employed, and high number of hospital treatments. The self report of good family relations was associated with both positive (strong belief in personal control) and negative illness perception (belief in serious consequences). Believing that external causes were predominantly responsible for the illness onset was related to the positive illness representation and to a lower education level Conclusion Illness perception in COPD patients is negative and associated with certain socio-demographic and illness/treatment-related characteristics; this may have implications for detecting and modifying negative perception patterns in patients at risk.

scholarly journals COPD AND GENDER AND OBESITY: IS THERE A LINK? A STUDY OF PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AMONG INNER CITY NEW YORKERS

CHEST Journal ◽  
2009 ◽  
Vol 136 (4) ◽  
pp. 50S
Author(s):  
Sucheta Pai ◽  
Veronica Fusco-Garcia ◽  
Miriam Lagunas-Fitta ◽  
Cristina Gutierrez ◽  
Balavenkatesh Kanna ◽  
...  
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Inner City ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
And Gender ◽  
New Yorkers

scholarly journals Healthcare Costs of Patients With Chronic Obstructive Pulmonary Disease in Denmark – Hospital Treated Versus Primary Care Only

2021 ◽  
Author(s):  
Jesper Lykkegaard ◽  
Jesper Bo Nielsen ◽  
Maria Munch Storsveen ◽  
Dorte Ejg Jarbøl ◽  
Jens Søndergaard
Keyword(s):  
Chronic Obstructive Pulmonary Disease ◽  
Primary Care ◽  
Pulmonary Disease ◽  
Secondary Care ◽  
Healthcare Costs ◽  
Hospital Treatment ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
And Gender ◽  
The Individual

Abstract Background: Many patients are treated for chronic obstructive pulmonary disease (COPD) in primary care but have never received COPD treatment in secondary care. They are seldom included in COPD cost studies but may account for a substantial proportion of the total costs.Objective: To estimate and specify the total healthcare costs of patients treated for COPD in Denmark comparing those who have- and have not had COPD treatment in secondary care.Setting: Denmark, population 5.7 million citizens.Methods: Via national registers, we specified the total healthcare costs of all +30-years-old current users of respiratory pharmaceuticals. We then compared those with at least one episode of hospital treatment for COPD (=secondary-care) to those with no hospital treatment for COPD but who redeem prescriptions specifically for COPD (=primary-care-only).Results: Among totally 329,428 users of respiratory drugs, we identified 46,084 with secondary-care- and 68,471 with primary-care-only COPD. Primary-care-only accounted for 40% of the two groups’ total healthcare costs. The age- and gender-adjusted coefficient relating the individual total costs secondary-care versus primary-care-only was 2.19. The individual costs ranged widely and overlapped considerably (p25-75: secondary-care 2,175€ - 12,625€, primary-care-only 1,110€ - 4,350€). Hospital treatment accounted for most of the total cost (secondary-care 78%, primary-care-only 62%; coefficient 2.81), pharmaceuticals (secondary-care 16%, primary-care-only 27%; coefficient 1.28), and primary care costs (secondary-care 6%, primary-care-only 11%; coefficient 1.13).Conclusion: Healthcare cost estimators and planners should consider the substantial volume of patients who are treated for COPD in primary care, but do not appear in hospital statistics.

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