Combined trabeculotomy-trabeculectomy versus Ahmed valve implantation for refractory primary congenital glaucoma in Egyptian patients: a long-term follow-up

Aim To determine the long-term outcomes of a cohort of complex patients with primary congenital glaucoma, aniridia and anterior segment dysgenesis. Methods Retrospective consecutive series between 1990–2021 in two UK tertiary centres: Guy's and St Thomas’ NHS Foundation Trust and King's College Hospital NHS Foundation Trust. We recorded the number and types of surgical and laser treatments along with preoperative and postoperative data, including intraocular pressures (IOP) and anti-glaucoma medications. Results A total of 41 eyes of 21 patients were included. Primary diagnoses were primary congenital glaucoma in 16 eyes (39.0%), aniridia in 14 eyes (34.2%), and anterior segment dysgenesis in 8 eyes (19.5%). Sixteen eyes (39.0%) had one or more glaucoma surgery or laser procedures for advanced glaucoma, and the long-term follow-up was 12.8 ± 3.6 years. There was a significant decrease in postoperative IOP (mmHg) at 3 months (16.5 ± 1.6; p = 0.0067), 6 months (18.7 ± 2.1; p = 0.0386), 12 months (18.6 ± 1.7; p = 0.0229), 3 years (14.7 ± 1.2; p = 0.0126), 5 years (15.5 ± 1.8; p = 0.0330) and 10 years (15.4 ± 2.3; p = 0.7780), compared to preoperatively (24.1 ± 2.6). Surgical success (complete and qualified) was 62.5%, 50.0%, 43.8%, 46.2%, 45.5% and 28.6% at 3 months, 6 months, 12 months, 3 years, 5 years and 10 years, respectively. There was no significant change in the number of anti-glaucoma drugs postoperatively ( p > 0.05). Four eyes (25.0%) had postoperative complications (hyphaema, hypotony) that resolved after conservative management. Conclusions Surgical management of these complex eyes with advanced glaucoma is challenging. Overall, the cohort had good surgical outcomes with a significant decrease in IOP by 36.1% after long-term follow-up.

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Evaluation of functional and morphological parameters in eyes with primary congenital glaucoma after trabeculectomy in the long-term follow-up

Klinika Oczna ◽

10.5114/ko.2018.82899 ◽

2018 ◽

Vol 2018 (4) ◽

pp. 200-204

Author(s):

Bronisława Koraszewska-Matuszewska ◽

Małgorzata Nita ◽

Andrzej Grzybowski

Keyword(s):

Congenital Glaucoma ◽

Morphological Parameters ◽

Primary Congenital Glaucoma ◽

Long Term Follow Up

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Mid- and Long-Term Follow-up after Percutaneous Pulmonary Valve Implantation in Children with the Melody Transcatheter Pulmonary Valve System

10.1055/s-0041-1725733 ◽

2021 ◽

Author(s):

P. Simmen ◽

V. Quiriconi ◽

D. Quandt ◽

W. Knirsch ◽

M. Christmann ◽

...

Keyword(s):

Pulmonary Valve ◽

Valve System ◽

Percutaneous Pulmonary Valve Implantation ◽

Long Term Follow Up ◽

Valve Implantation ◽

Percutaneous Pulmonary Valve ◽

Pulmonary Valve Implantation

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Transscleral Fixation of Black Diaphragm Intraocular Lens in Complete Aniridia and Aphakia Due to Posttraumatic Eye Rupture: A Pilot Study

Journal of Clinical Medicine ◽

10.3390/jcm8010046 ◽

2019 ◽

Vol 8 (1) ◽

pp. 46

Author(s):

Tomasz Chorągiewicz ◽

Katarzyna Nowomiejska ◽

Dariusz Haszcz ◽

Dominika Nowakowska ◽

Teresio Avitabile ◽

...

Keyword(s):

Intraocular Lens ◽

Anterior Segment ◽

Case Series ◽

Functional Restoration ◽

Long Term Outcomes ◽

Ahmed Valve ◽

Post Traumatic ◽

Valve Implantation

Introduction: To assess long-term outcomes of implantation of black diaphragm intraocular lens (BD IOL) in post-traumatic aniridia and aphakia due to eye rupture. Methods: This is a retrospective consecutive case series of 14 eyes with post-traumatic complete aniridia and aphakia treated with scleral fixation BD IOL. Measurements included ophthalmological comorbidities, best corrected visual acuity (BCVA), complications, and postoperative interventions. The average postoperative follow-up period was 36 months. Results: BCVA improved in 6 cases, was stable in 6 cases and worsened in 2 cases. The lens was well centered in 13 cases. Glaucoma was diagnosed in six cases developed, and three of them required Ahmed valve implantation. One lens developed opacity. The cornea was decompensated in 6 cases, while two of them required penetrating keratoplasty. Conclusion: Implantation of BD IOL in eyes with severely traumatized eyes enables reconstruction of the anterior segment and some functional restoration, although many complications may arise during the longitudinal follow-up.

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Long-term functional outcomes of different subtypes of primary congenital glaucoma

British Journal of Ophthalmology ◽

10.1136/bjophthalmol-2019-315131 ◽

2019 ◽

pp. bjophthalmol-2019-315131 ◽

Cited By ~ 2

Author(s):

Richard Sher Chaudhary ◽

Amisha Gupta ◽

Ajay Sharma ◽

Shikha Gupta ◽

Rayees Ahmad Sofi ◽

...

Keyword(s):

Visual Acuity ◽

Congenital Glaucoma ◽

Cumulative Probability ◽

Primary Congenital Glaucoma ◽

Visual Outcomes ◽

Post Surgery ◽

Kaplan Meier ◽

Significant Difference

AimTo analyse long-term visual outcomes across different subtypes of primary congenital glaucoma (PCG).MethodsPatients with PCG with a minimum of 5-year follow-up post surgery were included in the study. Snellen visual acuity recordings taken at their last follow-up were analysed. We evaluated the results using Kaplan-Meier curves to predict the probability of maintaining good vision (as defined by a visual acuity of 6/18 or better) in our patients after 30-year follow-up. The results were also analysed to determine whether there were any differences in the long-term visual acuities with time between the neonatal and infantile PCG. We also analysed the reasons for poor visual outcomes.ResultsWe assessed a cohort of 140 patients with PCG (235 eyes) with an average follow-up of 127±62.8 months (range 60–400 months). Overall, the proportion of eyes with good visual acuity was 89 (37.9%), those with fair visual acuity between 6/60 and 6/18 was 41 (17.4%), and those with poor visual acuity (≤6/60) was 105 (44.7%). We found a significant difference (p=0.047) between neonatal and infantile patients with PCG whereby the neonatal cohort fared worse off in terms of visual morbidity. On Kaplan-Meier analysis, the cumulative probability of survival of a visual acuity of 6/18 or better was more among the infantile PCG in comparison to the neonatal PCG (p=0.039) eyes, and more among the bilateral than the unilateral affected eyes (p=0.029). Amblyopia was the most important cause for poor visual acuity as shown on a Cox proportional-hazards regression model .ConclusionsLong-term visual outcomes of infantile are better than neonatal PCG. Eyes with unilateral have worse visual outcomes compared with those with bilateral PCG because of the development of dense amblyopia.

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Long-Term Follow-Up of Transcatheter Aortic Valve Implantation With Portico Versus Evolut Devices

The American Journal of Cardiology ◽

10.1016/j.amjcard.2020.01.018 ◽

2020 ◽

Vol 125 (8) ◽

pp. 1209-1215 ◽

Cited By ~ 1

Author(s):

Nicola Corcione ◽

Giuseppe Biondi-Zoccai ◽

Paolo Ferraro ◽

Alberto Morello ◽

Sirio Conte ◽

...

Keyword(s):

Aortic Valve ◽

Transcatheter Aortic Valve Implantation ◽

Transcatheter Aortic Valve ◽

Long Term Follow Up ◽

Aortic Valve Implantation ◽

Valve Implantation

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On the problem of the classification of congenital glaucoma

Russian Pediatric Ophthalmology ◽

10.18821/1993-1859-2016-11-4-179-183 ◽

2016 ◽

Vol 11 (4) ◽

pp. 179-183 ◽

Cited By ~ 1

Author(s):

L. A Katargina ◽

Andrei Olegovich Tarasenkov ◽

E. V Mazanova

Keyword(s):

Visual Acuity ◽

Age And Growth ◽

Congenital Glaucoma ◽

Initial Examination ◽

Anatomical Changes ◽

Long Term Follow Up ◽

Objective State

Objective. To monitor congenital glaucoma and to determine the proportion of the exposed stage of the disease revealed during the initial examination and the long-term follow up. Materials and methods. The present study included 27 children (47 eyes) at the age ranging from 8 to 17 years presenting with various forms of compensated congenital glaucoma at the initial, advanced, and terminal stages of the disease. Results. The clinical and functional characteristics of the eyes at each stage of congenital glaucoma were analyzed during the initial examination and the long-term follow-up period. It was found that the currently universally accepted classification of congenital glaucoma that subdivides the disease into stages based on the structural anatomical changes in the eyes ceases to adequately reflect the objective state of the visual system as the child grows. Conclusion. The study has demonstrated that the stage of congenital glaucoma needs to be corrected in accordance with the age and growth of the child and the possibility of its examination with the use of the psychophysical methods and the evaluation of visual acuity.

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