scholarly journals CORRECTION OF TINNITUS AND NEUROPSYCHOLOGICAL STATUS OF PATIENTS WITH CEREBRAL ATHEROSCLEROSIS AND ESSENTIAL HYPERTENSION USING CITICOLINE AS PART OF COMPREHENSIVE THERAPY

Author(s):  
T. M. Kuzmina ◽  
T. Yu. Vladimirova ◽  
M. A. Kachkovskiy ◽  
K. N. Melnikov ◽  
A. V. Seleznev ◽  
...  
2021 ◽  
Vol 25 (2(98)) ◽  
pp. 130-134
Author(s):  
S. Biletskyi

Literature data concerning the role of endothelium and nitric oxide in the pathogenesis of cardiovascular diseases, administration of L-arginine as a part of a comprehensive therapy of patients suffering from essential hypertension (EH) and ischemic heart disease (IHD) are cited.Objective: to systematize current literature data concerning the role of endothelium and nitric oxide in the pathogenesis of cardiovascular diseases, clinical experience of L-arginine administration in patients with EH and IHD. Conclusion. Nowadays endothelial dysfunction conception is defined with insufficient production of nitric oxide as a central part of EH and IHD pathogenesis. Nitric oxide deficiency occurring with cardiovascular diseases can be compensated by means of NO donors.


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