The role of low-dose dobutamine echocardiography in predicting response to biventricular pacing: results from the multicentre Viability in Cardiac Resynchronisation Therapy (ViaCRT) study

Author(s):  
Edyta Płońska-Gościniak ◽  
Jarosław D. Kasprzak ◽  
Tomasz Kukulski ◽  
Katarzyna Mizia-Stec ◽  
Ewa Nowalany-Kozielska ◽  
...  
2015 ◽  
Vol 4 (3) ◽  
pp. 3
Author(s):  
Antonio Curnis ◽  
David O’Donnell ◽  
Axel Kloppe ◽  
Žarko Calovic ◽  
◽  
...  

Cardiac resynchronisation therapy (CRT) using biventricular pacing is an established therapy for impairment of left ventricular (LV) systolic function in patients with heart failure (HF). Although technological advances have improved outcomes in patients undergoing biventricular pacing, the optimal placement of pacing leads remains challenging, and approximately one third of patients have no response to CRT. This may be due to patient selection and lead placement. Electrical mapping can greatly improve outcomes in CRT and increase the number of patients who derive benefit from the procedure. MultiPoint™ pacing (St Jude Medical, St Paul, MN, US) using a quadripolar lead increases the possibility of finding the best pacing site. In clinical studies, use of MultiPoint pacing in HF patients undergoing CRT has been associated with haemodynamic and clinical benefits compared with conventional biventricular pacing, and these benefits have been sustained at 12 months. This article describes the proceedings of a satellite symposium held at the European Heart Rhythm Association (EHRA) Europace conference held in Milan, Italy, in June 2015.


2021 ◽  
Vol 10 (1) ◽  
pp. 45-50
Author(s):  
Baldeep S Sidhu ◽  
Justin Gould ◽  
Mark K Elliott ◽  
Vishal Mehta ◽  
Steven Niederer ◽  
...  

Cardiac resynchronisation therapy is an important intervention to reduce mortality and morbidity, but even in carefully selected patients approximately 30% fail to improve. This has led to alternative pacing approaches to improve patient outcomes. Left ventricular (LV) endocardial pacing allows pacing at site-specific locations that enable the operator to avoid myocardial scar and target areas of latest activation. Left bundle branch area pacing (LBBAP) provides a more physiological activation pattern and may allow effective cardiac resynchronisation. This article discusses LV endocardial pacing in detail, including the indications, techniques and outcomes. It discusses LBBAP, its potential benefits over His bundle pacing and procedural outcomes. Finally, it concludes with the future role of endocardial pacing and LBBAP in heart failure patients.


2009 ◽  
Vol 18 ◽  
pp. S192
Author(s):  
Darryl P. Leong ◽  
Mitra Shirazi ◽  
Adhiraj Chakrabarty ◽  
Amy Penhall ◽  
Rebecca Perry ◽  
...  

2009 ◽  
Vol 17 (9) ◽  
pp. 354-357 ◽  
Author(s):  
S. Buck ◽  
A. H. Maass ◽  
D. J. van Veldhuisen ◽  
I. C. Van Gelder

2015 ◽  
pp. 119-126 ◽  
Author(s):  
Kevser G. Balci ◽  
Mustafa M. Balci ◽  
Fatih Sen ◽  
Ugur Canpolat ◽  
Mehmet Kadri Akboga ◽  
...  

2015 ◽  
Vol 1 (1) ◽  
pp. 35 ◽  
Author(s):  
Fang Fang ◽  
Zhou Yu Jie ◽  
Luo Xiu Xia ◽  
Liu Ming ◽  
Ma Zhan ◽  
...  

Chronic heart failure is still a major challenge for healthcare. Currently, cardiac resynchronisation therapy (CRT) has been incorporated into the updated guideline for patients with heart failure, left ventricular ejection fraction ≤35 % and prolonged QRS duration. With 20 years of development, the concept of ‘from bench to bedside’ has been illustrated in the field of CRT. Given the fact that the indications of CRT keep evolving, the role of CRT is not limited to the curative method for heart failure. We therefore summarise with the perspective of 5P medicine – preventive, personalised, predictive, participatory, promotive, to review the benefit of CRT in the prevention of heart failure in those with conventional pacemaker indications, the individualised assessment of patient’s selection, the predictor of responders of CRT, and the obstacles hindering the more application of CRT and the future development of this device therapy.


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