Anthelmintic Activity of Capsicum Annuum var. Longum (Siling-Haba) Placental Extracts Against Gastrointestinal Parasites in Broiler Chicken Stool

Phytotherapy may be an alternative strategy for controlling gastrointestinal parasites. This study evaluated the anthelmintic efficacy of Eucalyptus citriodora essential oil (EcEO). The in vitro effects of EcEO were determined through testing the inhibition of egg hatching and larval development of Haemonchus contortus. EcEO was subjected to acute toxicity testing on mice, orally and intraperitoneally. The in vivo effects of EcEO were determined by the fecal egg count reduction test (FECRT) in goats infected with gastrointestinal nematodes. The results showed that 5.3 mg.mL-1 EcEO inhibited egg hatching by 98.8% and 10.6 mg.mL-1 EcEO inhibited H. contortus larval development by 99.71%. The lethal doses for 50% of the mice were 4153 and 622.8 mg.kg-1, for acute toxicity orally and intraperitoneally. In the FECRT, the efficacy of EcEO and ivermectin was 66.25 and 79.16% respectively, on goat gastrointestinal nematodes eight days after treatment. EcEO showed in vitro and in vivo anthelmintic activity.

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Prosopis juliflora pods alkaloid-rich fraction: In vitro anthelmintic activity on goat gastrointestinal parasites and its cytotoxicity on vero cells

Pharmacognosy Magazine ◽

10.4103/pm.pm_3_17 ◽

2017 ◽

Vol 13 (51) ◽

pp. 684 ◽

Cited By ~ 3

Author(s):

Alexsandro Branco ◽

HelimarGonçalves Lima ◽

DaniloCavalcante Gomes ◽

NatháliaSilva Santos ◽

ÊuderReis Dias ◽

...

Keyword(s):

Anthelmintic Activity ◽

Vero Cells ◽

Prosopis Juliflora ◽

Gastrointestinal Parasites

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In vitro effects of Coriandrum sativum, Tagetes minuta, Alpinia zerumbet and Lantana camara essential oils on Haemonchus contortus

Revista Brasileira de Parasitologia Veterinária ◽

10.1590/s1984-29612013000400004 ◽

2013 ◽

Vol 22 (4) ◽

pp. 463-469 ◽

Cited By ~ 10

Author(s):

Iara Tersia Freitas Macedo ◽

Lorena Mayana Beserra de Oliveira ◽

Ana Lourdes Fernandes Camurça-Vasconcelos ◽

Wesley Lyeverton Correia Ribeiro ◽

Jessica Maria Leite dos Santos ◽

...

Keyword(s):

Essential Oils ◽

Larval Development ◽

Haemonchus Contortus ◽

Small Ruminants ◽

Anthelmintic Activity ◽

Gastrointestinal Parasites ◽

Coriandrum Sativum ◽

Tagetes Minuta ◽

Alpinia Zerumbet

Phytotherapy can be an alternative for the control of gastrointestinal parasites of small ruminants. This study evaluated the efficacy of Alpinia zerumbet, Coriandrum sativum, Tagetes minuta and Lantana camaraessential oils by two in vitro assays on Haemonchus contortus, an egg hatch test (EHT) and larval development test (LDT). No effect was observed for L. camara in the EHT. A. zerumbet, C. sativum and T. minuta essential oils exhibited a dose-dependent effect in the EHT, inhibiting 81.2, 99 and 98.1% of H. contortus larvae hatching, respectively, at a concentration of 2.5 mg mL-1. The effective concentration to inhibit 50% (EC50) of egg hatching was 0.94, 0.63 and 0.53 mg mL-1 for A. zerumbet, C. sativum and T. minuta essential oils, respectively. In LDT, L. camara, A. zerumbet, C. sativum and T. minuta at concentration of 10 mg mL-1 inhibited 54.9, 94.2, 97.8 and 99.5% of H. contortus larval development, presenting EC50 values of 6.32, 3.88, 2.89 and 1.67 mg mL-1, respectively. Based on the promising results presented in this in vitro model, it may be possible use of these essential oils to control gastrointestinal nematodes. However, their anthelmintic activity should be confirmed in vivo.

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