scholarly journals A Hospital Based Study in South Indian Population on the Role of Ultrasound in the Estimation of Gestational Age in the Third Trimester of Pregnancy

Author(s):  
Farhana Aljabri ◽  
Shar mila ◽  
K.S. Saraswathi ◽  
R. Shyamala
Biomedicine ◽  
2021 ◽  
Vol 40 (4) ◽  
pp. 436-441
Author(s):  
Kalpana Ramachandran ◽  
Arunthathy Gnaneshwar ◽  
Robert Dinesh Kumar ◽  
Parvathavarthine CR ◽  
Sri Santhana Krishnan V

Introduction and Aim: Gestational age assessment in women with indeterminate last menstrual period has always remained an enigma. Though multiple parameters have been found useful in providing an indirect age assessment, various studies have now shown that the ultrasonographic measurement of foetal kidney length during the second and third trimester of pregnancy is a viable alternative in foetal age assessment. Methods: This prospective study was conducted among the antenatal women with singleton uncomplicated pregnancy during 18 to 40 weeks of gestation attending the outpatient department for routine ultrasound foetal biometry in a tertiary care referral institution in South India, during January 2019 to June 2019. A total of hundred and thirty-five antenatal mothers were included in this study. Data entry was done in Microsoft Excel and data analysis was done using Statistical Package for Social Sciences (SPSS). Results: There was a strong positive correlation between GA and MKL. Regression model (Model 1) for Mean kidney length showed significant correlation and regression models (Model 2) for MKL and routine foetal biometric parameters like biparietal diameter, femur length and abdominal circumference were found to be significantly correlated. Conclusion: Mean foetal kidney length can alone predict gestational age and by combining it with the other biometric indices to give a better estimation of gestational age.


2013 ◽  
Vol 5 (3) ◽  
pp. 813-7 ◽  
Author(s):  
Lakkakula VKS Bhaskar ◽  
Sultana Mahin ◽  
Raju Thankabai Ginila ◽  
Periyasamy Soundararajan

2021 ◽  
Vol 19 (2) ◽  
pp. 16-21
Author(s):  
G Sasirekha ◽  

Background: Nitric oxide (endothelium derived relaxing factor) is synthesized from L-arginine by nitric oxide synthases. Endothelial NOS is responsible for most of the nitric oxide produced under physiological conditions. Acting via cGMP NO cause smooth muscle relaxation, prevents platelet aggregation and acts as an anti-inflammatory agent thereby playing a vital role in regulating vascular tone. Various studies have postulated the role of Nitricoxide in vascular disorders like hypertension and atherosclerosis. This study is aimed to find out the influence of endothelial nitric oxide synthase gene intron 4 VNTR polymorphism on Serum nitric oxide level among healthy South-Indian Population. Genotype analysis was done on 282 randomly selected healthy individuals by polymerase chain reaction. Phenotype analysis of eNOS activity was done by measuring serum NOx level. Significantly lower eNOS activity (10.5 versus 18.3, P value is < 0.00001) among ‘a’ alleles when compared to ‘b’ alleles. We have found the presence of eNOS ‘a’ allele is found to decrease serum NOx level. As the distribution of ‘a’allele is lower among the population, a larger study is needed to find the role of eNOS intron4 gene in maintaining serum Nitric oxide level.


Tumor Biology ◽  
2011 ◽  
Vol 32 (5) ◽  
pp. 1049-1053 ◽  
Author(s):  
Amar Chand Bhayal ◽  
B. Prabhakar ◽  
K. Pandu Ranga Rao ◽  
Anitha Penchikala ◽  
Qamar Ayesha ◽  
...  

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