scholarly journals Molecular Investigation of Rifampicin Resistance in Clinical Isolates of Mycobacterium ulcerans in Côte D'ivoire

Author(s):  
Bakary Coulibaly ◽  
David N’golo Coulibaly ◽  
Clément Kouassi Kouassi ◽  
Ibrahim Konaté ◽  
Elise Solange Ngazoa Kakou ◽  
...  
Author(s):  
Philippe Bahadoran ◽  
Nassim Hammoudi ◽  
Alice Gaudart ◽  
Jamal Saad ◽  
Yoan Di Filippo ◽  
...  

Mycobacterium ulcerans, the opportunistic pathogen causing Buruli ulcer, is reported to affect rural populations in 36 tropical countries. We report one case of Buruli ulcer in a peri-urban area in Côte d’Ivoire, confirmed by whole genome sequencing which indicated a M. ulcerans genotype previously unreported in Côte d’Ivoire.


2020 ◽  
Vol 14 (5) ◽  
pp. e0008228
Author(s):  
Nassim Hammoudi ◽  
Sylvestre Dizoe ◽  
Jamal Saad ◽  
Evans Ehouman ◽  
Bernard Davoust ◽  
...  

2016 ◽  
Vol 12 (30) ◽  
pp. 263
Author(s):  
Adjet A. Abel ◽  
Adou D. Lucien ◽  
Danièle O. Konan

Buruli ulcer is an infectious disease caused by Mycobacterium ulcerans. It begins with a lump, swelling, skin plate and progresses to severe ulceration and disabling sequelae . For over a decade, it is a real public health problem in Côte d'Ivoire. The institutions responsible for the fight against this disease advocate for patients in endemic areas early case detection and immediate recourse to specialized care centers. Despite this recommendation, the therapeutic itinerary of patients is multimodal. This study aims to analyze the therapeutic itinerary plural sick of Buruli ulcer and to determine the factors that justify the paradoxes and contradictions between state recommendations and behaviors of patients. It took place in three support centers in the health district of yamoussoukro. In a qualitative approach, with observation checklists, interview guides, this study was conducted with 50 patients, 18 healers in the care center and 4 traditional healers. Patients rely successively, alternatively or additionally to the African medicine and care center. Traditional medicine is the first therapeutic choice for most patients. The proximity of traditional healer, cultural beliefs and representations related to the disease, the constraints of hospitalization, ignorance of the disease make account plural therapeutic itineraries sick of Buruli ulcer.The patients do not adhere to early detection and immediate access to health care centers. Free medical care for Buruli ulcer is fraught with difficulties because of patient behaviors. The hospital management does not consider the social environment of patients and the relationship between the disease and culture that influence the therapeutic itinerary of patients.


2010 ◽  
Vol 5 (01) ◽  
pp. 059-063 ◽  
Author(s):  
Grossmann Marie-David Coulibaly-N´Golo ◽  
Euloge Ekaza ◽  
Bakary Coulibaly ◽  
N’guetta Aka ◽  
Raymond Kouassi N’Guessan ◽  
...  

Introduction: Buruli ulcer, caused by Mycobacterium ulcerans, is endemic in more than 30 countries worldwide, with Côte d'Ivoire being among the most affected countries. Methodology: We used seven variable number of tandem repeats (VNTR) markers and analyzed 114 samples from 11 Ivorian localities consisting of 33 bacterial strains and 81 clinical samples. Complete data sets at loci 1, 6, 9 and 33 were obtained for 18 of these strains (n = 15) and samples (n = 3) collected in each of the localities. Results: All the strains had allelic profile [3113], corresponding to the previously described Atlantic Africa genotype. Conclusion: Sequencing of PCR products at all loci showed no variation in sequence or repeat number, underlining the genetic monomorphism of M. ulcerans in Côte d'Ivoire.


Author(s):  
Anselme Millogo ◽  
Dezemon Zingue ◽  
Amar Bouam ◽  
Sylvain Godreuil ◽  
Michel Drancourt ◽  
...  

Environmental Mycobacterium ulcerans causes a disabling skin disease called Buruli ulcer. Recent studies completed the knowledge of the evolving geographic extension and epidemiology of Buruli ulcer in West Africa, where Côte d’Ivoire is reporting the highest number of cases. We report seven polymerase chain reaction-documented patients in Burkina Faso, a neighboring country of Côte d’Ivoire, where previously Buruli ulcer cases were confirmed primarily using clinical arguments.


2015 ◽  
Vol 7 (4) ◽  
pp. 163-171 ◽  
Author(s):  
Kakou Solange ◽  
Coulibaly David ◽  
Aka Nguetta ◽  
Vakou Sabine ◽  
Aoussi Serge ◽  
...  

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