scholarly journals Omics in Aid of Host-pathogen Interaction Studies: A Bacterial Perspective

Author(s):  
Ursula Fels ◽  
Kris Gevaert ◽  
Petra Van Damme

By providing useful tools to study host-pathogen interactions, next-generation omics has recently enabled the study of gene expression changes in both pathogen and infected host simultaneously. However, since great discriminative power is required to study pathogen and host simultaneously throughout the infection process, the depth of quantitative gene expression profiling has proven to be unsatisfactory when focusing on bacterial pathogens, thus preferentially requiring specific strategies or the development of novel methodologies based on complementary omics approaches. In this review, we focus on the difficulties encountered when making use of omics approaches to study bacterial pathogenesis. Besides, we review different omics strategies (i.e. transcriptomics, proteomics and secretomics) and their applications for studying interactions of pathogens with their host.

2004 ◽  
Vol 20 (15) ◽  
pp. 2390-2398 ◽  
Author(s):  
Y. Zhang ◽  
D. A. Eberhard ◽  
G. D. Frantz ◽  
P. Dowd ◽  
T. D. Wu ◽  
...  

2006 ◽  
Vol 352 (1) ◽  
pp. 50-60 ◽  
Author(s):  
Michael Flagella ◽  
Son Bui ◽  
Zhi Zheng ◽  
Cung Tuong Nguyen ◽  
Aiguo Zhang ◽  
...  

2011 ◽  
Vol 81A (1) ◽  
pp. 72-80 ◽  
Author(s):  
Ditte Caroline Andersen ◽  
Gitte Qvist Kristiansen ◽  
Line Jensen ◽  
Ernst-Martin Füchtbauer ◽  
Henrik Daa Schrøder ◽  
...  

Gene Reports ◽  
2019 ◽  
Vol 14 ◽  
pp. 25-29
Author(s):  
Venkatrao Vantaku ◽  
Vinod K. Chauhan ◽  
Narender K. Dhania ◽  
Balasubramanian Senthilkumaran ◽  
Aparna Dutta-Gupta

2008 ◽  
Vol 23 (6) ◽  
pp. 1346-1352 ◽  
Author(s):  
Daniel S. Oh ◽  
Steven R. DeMeester ◽  
Christy M. Dunst ◽  
Ryutaro Mori ◽  
Bethany J. Lehman ◽  
...  

2004 ◽  
Vol 48 (1) ◽  
pp. 23-29 ◽  
Author(s):  
Andrea Jochheim ◽  
Tina Hillemann ◽  
Gabriela Kania ◽  
Jennifer Scharf ◽  
Masoumeh Attaran ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document