scholarly journals Managementof squamos cell carcinoma of tongue in young men: case report

2019 ◽  
Vol 1 (1) ◽  
pp. 21
Author(s):  
Israyani Israyani ◽  
Ayu F. Argadianti ◽  
Hening Tuti Hendarti ◽  
Adiastuti E. P

Background: Oral Squamous cell carcinoma is the most common malignant neoplasm of the oral cavity, usually affecting individuals over 50 years of age. It rarely occurs in patients who are less than 40 years old. Purpose: This case report aim is to focuses on establishment of diagnosis, differential diagnosis, predisposition, and treatment planning related to the case. Case: This report describes a case of oral squamous cell carcinoma, staged T1N1M0 (stage III), involving the lateral border and ventral surface of the tongue of a 32-year old male patient, with no smoking or drinking habits. Initial tumor presentation was of deep ulceration and intense pain. Case Management: Patient has examination with autofluorence LED light, presence of bacterial growth, and FNA for establised diagnosis. Patient was given chlorine dioxide mouthwash and education for further treatment one of them is tomoterapi. Conclusions: Clinical features of deep ulceration, pain and induration may be a suspicious feature of oral cavity cancer, therefore early diagnosis of oral squamous cell carcinoma determines prognosis.Keywords: malignant, autofluoresence, tomoterap

Author(s):  
Roberto da Silva de Almeida

The objective of this work was to describe clinically, surgically and immediate oral rehabilitation of a patient with aggressive oral squamous cell carcinoma, or the most frequent in the oral cavity, in which the majority are frequent and treated with resection and subsequent rehabilitation.


2020 ◽  
Vol 10 (1) ◽  
pp. 3-5
Author(s):  
Parometa Barma ◽  
Ibrahim Khalil ◽  
Tanzima Yeasmin

Developing country like Bangladesh among 90% of oral malignant neoplasm are arising from squamous layer of oral epithelium which are third leading of this country with severe disfiguration, functiolaesa, psychological impairments and socio-economic hardship. In this study we found the prevalence of OSCC was 6.5% among total cancer patients in the two tertiary level hospitals of Bogura. Male (70%) are affected more than in females (30%). In response to male and female parameter, sex distribution ratio was 2.3:1. The prevalent average age was 55.40 years. About 80% of ulcer site was buccal mucosa then 10 % were lip mucosa. About 80% people were habituated by betel nut, leaf with tobacco chewers. Moreover 46.7% of them were maltreated by quack doctors before. Majority of the patient was in Grade II (56.7%). Correlation between variable in respect of age and cancer grading was explained. According to these study OSCC patients in north bangle region like Bogura was quite high on ( significant p-value ≤ 0.05). Description of oral squamous cell carcinoma on the basis of demographic and clinical profile was the major aim . Most of the cases report with intermediate grade of the disease which often leads to decrease the chance of survival of a patient. So new strategies should be considered to overcome the present situation must be undertaken by oral health programs for the early diagnosis and prevention, build up awareness and management and follow up of oral cancer. Update Dent. Coll. j: 2020; 10 (1): 3-5


2016 ◽  
Vol 19 (2) ◽  
pp. 61-70 ◽  
Author(s):  
T-T Dong ◽  
L-J Wang ◽  
L-Z Liu ◽  
S-N Ma

AbstractIn order to investigate the association between polymorphisms in genes encoding metabolizing enzymes (CYP1A1-MspI, EC-SOD (extracellular superoxide dismutase), GSTT1, GSTM1, ALDH2), cigarette and alcohol consumption, and the risk of oral squamous cell carcinoma, we conducted a prospective case-control study comprised of 750 individuals with oral squamous cell carcinoma (OSCC) and 750 healthy individuals. Data about smoking and drinking habits were collected along with other demographic and clinical information. Peripheral blood samples were collected for DNA extraction, and polymerase chain reaction (PCR) and PCR-RFLP (restriction fragment length polymorphism) were used to determine genotypes of CYP1A1, EC-SOD, GSTT1, GSTM1, ALDH2. The results showed that smoking and alcohol consumption were significantly more common among patients than controls (p <0.05). There were significant differences in the genotype distribution for each locus between groups, with the CYP1A1 (m2/ m2), EC-SOD (C/G), GSTT1 [–], GSTM1 [–] and ALDH2 (non G/G) genotypes being more common among patients (p <0.05). Furthermore, the majority of patients had at least two or more variant genotypes, while controls had one or no variant genotype (p <0.05). Finally, multiple variant genotypes combined with smoking, drinking, or both smoking and drinking significantly increased the risk of OSCC, with greater increase for heavier smoking/drinking. In brief, genetic polymorphism of CYP1A1, EC-SOD, GSTT1, GSTM1, and ALDH2 and smoking and drinking history are closely associated with susceptibility to OSCC.


2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Matthias Christian Wurm ◽  
Emeka Nkenke ◽  
Friedrich-Wilhelm Neukam ◽  
Tobias Möst ◽  
Rainer Lutz ◽  
...  

Author(s):  
ELEN DE SOUZA TOLENTINO ◽  
MAILON CURY CARNEIRO ◽  
TALITA DE CARVALHO KIMURA ◽  
NELI PIERALISI ◽  
VANESSA CRISTINA VELTRINI

Author(s):  
CAMILA GUIMARÃES DE SOUSA ◽  
RAELLY KATHARINNE LIMA DE MENESES ◽  
LUAN ÉVERTON GALDINO BARNABÉ ◽  
RAFAEL GROTTA GREMPEL ◽  
CASSIANO FRANCISCO WEEGE NONAKA ◽  
...  

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Seba Abraham ◽  
Bhagyalekshmi Mallika ◽  
Arunima Reshma ◽  
ReejaMol Mohammed Kassim

Oral squamous cell carcinoma is the most common type of oral malignant neoplasm. As per literature, squamous cell carcinomas of the alveolar ridge account for 9% of all the oral carcinomas. The oral squamous cell carcinoma shares clinical similarity with various forms of inflammatory gingival lesions and is often misdiagnosed in our routine dental practice. The dentist should have precise knowledge regarding the clinical manifestation of this deadly disease as early diagnosis and prompt treatment can reduce morbidity and mortality of the disease.


2020 ◽  
Vol 130 (3) ◽  
pp. e213-e214
Author(s):  
MYCAELLE STEPHANNY DAS NEVES BARBOSA SENA ◽  
CLAYTON CLENISSON DE CARVALHO SILVA ◽  
VANESSA DE CARLA BATISTA DOS SANTOS ◽  
LARISSA TINô DE CARVALHO SILVA ◽  
INGRID FERREIRA LEITE ◽  
...  

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