scholarly journals MSEICR Fractional Order Mathematical Model of The Spread Hepatitis B

2020 ◽  
Vol 17 (2) ◽  
pp. 314-324
Author(s):  
Suriani Suriani ◽  
Syamsuddin Toaha ◽  
Kasbawati Kasbawati

This research aims to develop the MSEICR model by reviewing fractional orders on the spread of Hepatitis B by administering vaccinations and treatment, and analyzing fractional effects by numerical simulations of the MSEICR mathematical model using the method Grunwald Letnikov. Researchers use qualitative methods to achieve the object of research. The steps are to determine the MSEICR model by reviewing the fractional order, looking for endemic equilibrium points for each non-endemic and endemic equilibrium point, determining the equality of characteristics and eigenvalues ​​of the Jacobian matrix. Next, look for values  ​​(Basic Reproductive Numbers), analyze stability around non-endemic and endemic equilibrium points and complete numerical simulations. From the simulation provided, it is known that by giving a fractional alpha value of and  , the greater the value of the fractional order parameters used, the movement of the solution graphs is getting closer to the equilibrium point. If given and still endemic, whereas if and  the value  is increased to non-endemic, then the number of hepatitis B sufferers will disappear.

2021 ◽  
Vol 2 (2) ◽  
pp. 68-79
Author(s):  
Muhammad Manaqib ◽  
Irma Fauziah ◽  
Eti Hartati

This study developed a model for the spread of COVID-19 disease using the SIR model which was added by a health mask and quarantine for infected individuals. The population is divided into six subpopulations, namely the subpopulation susceptible without a health mask, susceptible using a health mask, infected without using a health mask, infected using a health mask, quarantine for infected individuals, and the subpopulation to recover. The results obtained two equilibrium points, namely the disease-free equilibrium point and the endemic equilibrium point, and the basic reproduction number (R0). The existence of a disease-free equilibrium point is unconditional, whereas an endemic equilibrium point exists if the basic reproduction number is more than one. Stability analysis of the local asymptotically stable disease-free equilibrium point when the basic reproduction number is less than one. Furthermore, numerical simulations are carried out to provide a geometric picture related to the results that have been analyzed. The results of numerical simulations support the results of the analysis obtained. Finally, the sensitivity analysis of the basic reproduction numbers carried out obtained four parameters that dominantly affect the basic reproduction number, namely the rate of contact of susceptible individuals with infection, the rate of health mask use, the rate of health mask release, and the rate of quarantine for infected individuals.


Author(s):  
Conghui Xu ◽  
Yongguang Yu ◽  
YangQuan Chen ◽  
Zhenzhen Lu

AbstractIn this paper, a generalized fractional-order SEIR model is proposed, denoted by SEIQRP model, which has a basic guiding significance for the prediction of the possible outbreak of infectious diseases like COVID-19 and other insect diseases in the future. Firstly, some qualitative properties of the model are analyzed. The basic reproduction number R0 is derived. When R0 < 1, the disease-free equilibrium point is unique and locally asymptotically stable. When R0 > 1, the endemic equilibrium point is also unique. Furthermore, some conditions are established to ensure the local asymptotic stability of disease-free and endemic equilibrium points. The trend of COVID-19 spread in the United States is predicted. Considering the influence of the individual behavior and government mitigation measurement, a modified SEIQRP model is proposed, defined as SEIQRPD model. According to the real data of the United States, it is found that our improved model has a better prediction ability for the epidemic trend in the next two weeks. Hence, the epidemic trend of the United States in the next two weeks is investigated, and the peak of isolated cases are predicted. The modified SEIQRP model successfully capture the development process of COVID-19, which provides an important reference for understanding the trend of the outbreak.


2018 ◽  
Vol 13 (1) ◽  
pp. 9 ◽  
Author(s):  
Weronika Wojtak ◽  
Cristiana J. Silva ◽  
Delfim F.M. Torres

We propose a Caputo type fractional-order mathematical model for the transmission dynamics of tuberculosis (TB). Uniform asymptotic stability of the unique endemic equilibrium of the fractional-order TB model is proved, for anyα∈ (0, 1). Numerical simulations for the stability of the endemic equilibrium are provided.


2012 ◽  
Vol 26 (14) ◽  
pp. 1250075 ◽  
Author(s):  
GUANGHUI SUN ◽  
MAO WANG

A new fractional order chaotic n-scroll modified Chua circuit is introduced. It can generate n-scroll with a total order less than three. The equilibrium points are classified into two types according to the characteristics of the eigenvalues of the Jacobian matrix at the equilibrium points. To overcome some disadvantages of the traditional fractional order controller, a new fractional order control method is developed for stabilizing the system to any expected equilibrium point. Numerical examples are provided to verify the effectiveness of the proposed scheme.


2021 ◽  
Vol 15 (2s) ◽  
pp. 1-18
Author(s):  
Ebenezar Nkemjika Unaegbu ◽  
Ifeanyi Sunday Onah ◽  
Moses Oladotun Oyesanya

Background: HIV is a virus that is directed at destroying the human immune system thereby exposing the human body to the risk of been affected by other common illnesses and if it is not treated, it generates a more chronic illness called AIDS. Materials and Methods: In this paper, we employed the fixed-point theory in developing the uniqueness and existence of a solution of fractional order HIV/AIDS model having Caputo-Fabrizio operator. This approach adopted in this work is not conventional when solving biological models by fractional derivatives. Results: The results showed that the model has two equilibrium points namely, disease-free, and endemic equilibrium points, respectively. We showed conditions necessitating the existence of the endemic equilibrium point and showed that the disease-free equilibrium point is locally asymptotically stable. We also tested the stability of our solution using the iterative Laplace transform method on our model which was also shown stable agreeing with the disease-free equilibrium. Conclusions: Numerical simulations of our model showed clear comparison with our analytical results. The numerical solutions show that given fractional operator like the Caputo-Fabrizio operator, it is less noisy and plays a major role in making a precise decision and gives room (‘freedom’) to use data of specific patients as the model can be easily adjusted to accommodate this, as it a better fit for the patients’ data and provide meaningful predictions. Finally, the result showed the advantage of using fractional order derivative in the analysis of the dynamics of HIV/AIDS over the classical case.


2020 ◽  
Vol 17 (2) ◽  
pp. 202-218
Author(s):  
Rusniwati S. Imran ◽  
Resmawan Resmawan ◽  
Novianita Achmad ◽  
Agusyarif Rezka Nuha

This research discussed the SEIPR mathematical model on the spread of pneumonia among children under five years old. The development of the model was done by considering factors of immunization and treatment factors, in an effort to reduce the rate of spread of pneumonia. In this research, mathematical model construction, stability analysis, and numerical simulation were carried out to see the dynamics of pneumonia cases in the population. The model analysis produces two equilibrium points, which are the equilibrium point without the disease, the endemic equilibrium point, and the basic reproduction number ( ) as the threshold value for disease spread. The point of equilibrium without disease reaches a stable state at the moment , which indicates that pneumonia will disappear from the population, while the endemic equilibrium point reaches a stable state at that time , which indicates that the disease will spread in the population. Furthermore, numerical simulations show that increasing the rate parameters of infected individuals undergoing treatment ( ), the treatment success rate ( ), and the immunization proportion ( ), could suppress the basic reproductive number so that control of the disease spread rate can be accelerated.


2020 ◽  
Vol 1 (2) ◽  
pp. 71-80
Author(s):  
Anisa Fitra Dila Hubu ◽  
Novianita Achmad ◽  
Nurwan Nurwan

This study discusses the spread of measles in a mathematical model. Mathematical modeling is not only limited to the world of mathematics but can also be applied in the health sector. Measles is a disease with a high transmission rate. The spread of measles in this model was modified by adding the treated population and the treatment parameters of the exposed population. In this article, we examine the equilibrium points in the SMEIUR mathematical model and perform stability analysis and numerical simulations. In this study, two equilibrium points were obtained, namely the disease-free and endemic equilibrium point. After getting the equilibrium point, an analysis is carried out to find the stability of the model. Furthermore, the simulation produces a stable disease-free equilibrium point at conditions R01 and a stable endemic equilibrium point at conditions R01. In this study, a numerical simulation was carried out to see population dynamics by varying the parameter values. The simulation results show that to reduce the spread of measles, it is necessary to increase the rate of advanced immunization, the rate of the infected population undergoing treatment, and the proportion of individuals who are treated cured.


Author(s):  
Oluwafemi Temidayo J. ◽  
Azuaba E. ◽  
Lasisi N. O.

In this study, we analyzed the endemic equilibrium point of a malaria-hygiene mathematical model. We prove that the mathematical model is biological and meaningfully well-posed. We also compute the basic reproduction number using the next generation method. Stability analysis of the endemic equilibrium point show that the point is locally stable if reproduction number is greater that unity and globally stable by the Lasalle’s invariant principle. Numerical simulation to show the dynamics of the compartment at various hygiene rate was carried out.


2019 ◽  
Vol 10 (4) ◽  
pp. 355-376
Author(s):  
Shashi Kant

AbstractIn this paper, we investigate the deterministic and stochastic prey-predator system with refuge. The basic local stability results for the deterministic model have been performed. It is found that all the equilibrium points except the positive coexisting equilibrium point of the deterministic model are independent of the prey refuge. The trivial equilibrium point, predator free equilibrium point and prey free equilibrium point are always unstable (saddle point). The existence and local stability of the coexisting equilibrium point is related to the prey refuge. The permanence and extinction conditions of the proposed biological model have been studied rigourously. It is observed that the stochastic effect may be seen in the form of decaying of the species. The numerical simulations for different values of the refuge values have also been included for understanding the behavior of the model graphically.


Fractals ◽  
2021 ◽  
Author(s):  
HUSSAM ALRABAIAH ◽  
MATI UR RAHMAN ◽  
IBRAHIM MAHARIQ ◽  
SAMIA BUSHNAQ ◽  
MUHAMMAD ARFAN

In this paper, we consider a fractional mathematical model describing the co-infection of HBV and HCV under the non-singular Mittag-Leffler derivative. We also investigate the qualitative analysis for at least one solution and a unique solution by applying the approach fixed point theory. For an approximate solution, the technique of the iterative fractional order Adams–Bashforth scheme has been implemented. The simulation for the proposed scheme has been drawn at various fractional order values lying between (0,1) and integer-order of 1 via using Matlab. All the compartments have shown convergence and stability with time. A detailed comparative result has been given by the different fractional orders, which showed that the stability was achieved more rapidly at low orders.


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