scholarly journals Severe and enduring Anorexia Nervosa: a brief narrative review about the concept and its therapeutic options

2019 ◽  
pp. 3
Author(s):  
Francisco Coutinho ◽  
Isabel Brandão
Keyword(s):  
Anorexia Nervosa ◽  
Narrative Review ◽  
Therapeutic Options

scholarly journals Medication-Related Osteonecrosis of the Jaw: A Critical Narrative Review

2021 ◽  
Vol 10 (19) ◽  
pp. 4367
Author(s):  
Alejandro I. Lorenzo-Pouso ◽  
José Bagán ◽  
Leticia Bagán ◽  
Pilar Gándara-Vila ◽  
Cintia M. Chamorro-Petronacci ◽  
...  
Keyword(s):  
Relevant Literature ◽  
Osteonecrosis Of The Jaw ◽  
Narrative Review ◽  
Therapeutic Options ◽  
Current Understanding ◽  
Published Data ◽  
Paradoxical Reaction ◽  
Current Trends ◽  
Orofacial Region

Background: Nearly two decades have passed since a paradoxical reaction in the orofacial region to some bone modifying agents and other drugs was recognized, namely medication-related osteonecrosis of the jaw (MRONJ). Purpose: The aim of this manuscript was to critically review published data on MRONJ to provide an update on key terminology, concepts, and current trends in terms of prevention and diagnosis. In addition, our objective was to examine and evaluate the therapeutic options available for MRONJ. Methods: The authors perused the most relevant literature relating to MRONJ through a search in textbooks and published articles included in several databases for the years 2003–2021. Results and conclusions: A comprehensive update of the current understanding of these matters was elaborated, addressing these topics and identifying relevant gaps of knowledge. This review describes our updated view of the previous thematic blocks, highlights our current clinical directions, and emphasizes controversial aspects and barriers that may lead to extending the accumulating body of evidence related to this severe treatment sequela.

scholarly journals To Improve the Initial Inpatient Management of Adolescents Admitted with Severe Anorexia Nervosa: A Narrative Review and a Convenient Protocol

Nutrients ◽  
2022 ◽  
Vol 14 (1) ◽  
pp. 229
Author(s):  
Stephanie Proulx-Cabana ◽  
Marie-Elaine Metras ◽  
Danielle Taddeo ◽  
Olivier Jamoulle ◽  
Jean-Yves Frappier ◽  
...  
Keyword(s):  
Anorexia Nervosa ◽  
Caloric Intake ◽  
Tube Feeding ◽  
Narrative Review ◽  
Cardiac Monitoring ◽  
Current Evidence ◽  
Cardiac Complications ◽  
Nutritional Rehabilitation ◽  
Refeeding Syndrome ◽  
Pubmed Search

Inadequate nutritional rehabilitation of severely malnourished adolescents with Anorexia Nervosa (AN) increases the risk of medical complications. There is no consensus on best practices for inpatient nutritional rehabilitation and medical stabilization for severe AN. This study aimed to elaborate an admission protocol for adolescents with severe AN based on a comprehensive narrative review of current evidence. A Pubmed search was conducted in July 2017 and updated in August 2020, using the keywords severe AN or eating disorders (ED), management guidelines and adolescent. Relevant references cited in these guidelines were retrieved. A secondary search was conducted using AN or ED and refeeding protocol, refeeding syndrome (RS), hypophosphatemia, hypoglycemia, cardiac monitoring or cardiac complications. Evidence obtained was used to develop the admission protocol. Selective blood tests were proposed during the first three days of nutritional rehabilitation. Higher initial caloric intake is supported by evidence. Continuous nasogastric tube feeding was proposed for patients with a BMI < 12 kg/m2. We monitor hypoglycemia for 72 h. Continuous cardiac monitoring for bradycardia <30 BPM and systematic phosphate supplementation should be considered. Developing protocols is necessary to improve standardization of care. We provide an example of an inpatient admission protocol for adolescents with severe AN.

scholarly journals Coronavirus Disease 19 (COVID-19) Pharmacologic Treatment

2021 ◽  
Vol 40 (4) ◽  
pp. 134-147
Author(s):  
Nikolina Bogdanić ◽  
Ljiljana Lukić ◽  
Josip Begovac
Keyword(s):  
Pharmacological Treatment ◽  
Diagnostic Tests ◽  
Viral Genome ◽  
Narrative Review ◽  
Therapeutic Options ◽  
Pharmacologic Treatment ◽  
Short Narrative

Since the first cases of COVID-19 were reported from China the disease became pandemic within a few months. The viral genome was sequenced soon after the outbreak of COVID-19 which enabled development of diagnostic tests and therapeutic options. As the knowledge of SARS-CoV-2 virology increased, many potential drugs appeared. At this moment (January 12th 2021), 4426 studies of COVID-19 are registered, and more than 2680 studies are investigating therapeutic options. This is a short narrative review of currently available evidence on pharmacological treatment of COVID-19.

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