scholarly journals Coronavirus Disease 19 (COVID-19) Pharmacologic Treatment

2021 ◽  
Vol 40 (4) ◽  
pp. 134-147
Author(s):  
Nikolina Bogdanić ◽  
Ljiljana Lukić ◽  
Josip Begovac
Keyword(s):  
Pharmacological Treatment ◽  
Diagnostic Tests ◽  
Viral Genome ◽  
Narrative Review ◽  
Therapeutic Options ◽  
Pharmacologic Treatment ◽  
Short Narrative

Since the first cases of COVID-19 were reported from China the disease became pandemic within a few months. The viral genome was sequenced soon after the outbreak of COVID-19 which enabled development of diagnostic tests and therapeutic options. As the knowledge of SARS-CoV-2 virology increased, many potential drugs appeared. At this moment (January 12th 2021), 4426 studies of COVID-19 are registered, and more than 2680 studies are investigating therapeutic options. This is a short narrative review of currently available evidence on pharmacological treatment of COVID-19.

Neurology and Pregnancy

2021 ◽  
pp. 1177-1184
Author(s):  
Lauren M. Jackson ◽  
Deena M. Nasr
Keyword(s):  
Disease Management ◽  
Diagnostic Tests ◽  
Therapeutic Options ◽  
Neurologic Diseases ◽  
Risks And Benefits

Pregnancy is a time of many physiologic and systemic changes that may predispose women to new neurologic diseases or alter the course of preexisting disease. Management of neurologic diseases during pregnancy is complicated by the risks and benefits to both mother and fetus that must be weighed when diagnostic tests and therapeutic options are selected.

A short narrative review of the feasibility of adopting mild ovarian stimulation for IVF as the current standard of care

2012 ◽  
Vol 286 (2) ◽  
pp. 505-510 ◽  
Author(s):  
Charalampos Siristatidis ◽  
Marialena Trivella ◽  
Charalampos Chrelias ◽  
Vasileios D. Sioulas ◽  
Nikolaos Vrachnis ◽  
...  
Keyword(s):  
Ovarian Stimulation ◽  
Standard Of Care ◽  
Narrative Review ◽  
Current Standard ◽  
Mild Ovarian Stimulation ◽  
Short Narrative

scholarly journals Tratamento farmacológico da cardiomiopatia hipertrófica em adultos - uma revisão narrativa / Pharmacological treatment of hypertrophic cardiomyopathy in adults - a narrative review

2020 ◽  
Vol 3 (4) ◽  
pp. 11855-11871
Author(s):  
Artur Ferri Leite Storino ◽  
Thaís Moreira Martins da Costa ◽  
Norma Ávila da Silveira ◽  
Tainá Ávila da Silveira ◽  
João Ricardo Arraes Oliveira ◽  
...  
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Pharmacological Treatment ◽  
Narrative Review

scholarly journals Saliva sampling is an excellent option to increase the number of SARS CoV2 diagnostic tests in settings with supply shortages

2020 ◽  
Author(s):  
Joaquín Moreno-Contreras ◽  
Marco A. Espinoza ◽  
Carlos Sandoval-Jaime ◽  
Marco A. Cantú-Cuevas ◽  
Héctor Barón-Olivares ◽  
...  
Keyword(s):  
Diagnostic Tests ◽  
Viral Genome ◽  
Laboratory Testing ◽  
Diagnostic Procedure ◽  
Viral Rna ◽  
Healthcare Personnel ◽  
High Demand ◽  
Rna Detection ◽  
Golden Standard ◽  
Classical Protocol

AbstractAs part of any plan to lift or ease the confinement restrictions that are in place in many different countries, there is an urgent need to increase the capacity of laboratory testing for SARS CoV-2. Detection of the viral genome through RT-qPCR is the golden standard for this test, however, the high demand of the materials and reagents needed to sample individuals, purify the viral RNA, and perform the RT-qPCR test has resulted in a worldwide shortage of several of these supplies. Here, we show that directly lysed saliva samples can serve as a suitable source for viral RNA detection that is cheaper and can be as efficient as the classical protocol that involves column purification of the viral RNA. In addition, it surpasses the need for swab sampling, decreases the risk of the healthcare personnel involved in this process, and accelerates the diagnostic procedure.

scholarly journals Pharmacologic Treatment for Pediatric Gastroparesis: A Review of the Literature

2016 ◽  
Vol 21 (2) ◽  
pp. 120-132 ◽  
Author(s):  
Emma M. Tillman ◽  
Keaton S. Smetana ◽  
Likeselam Bantu ◽  
Merrion G. Buckley
Keyword(s):  
Pharmacological Treatment ◽  
Treatment Options ◽  
Disease State ◽  
Adult Patients ◽  
Clear Correlation ◽  
Pharmacologic Treatment ◽  
Review Of The Literature ◽  
Future Studies ◽  
The Past ◽  
Associated Symptoms

There have been a number of agents that have been tried for treatment of gastroparesis over the past 3 decades, with varying levels of success. Guidelines exist for the management of gastroparesis in adults; however, even though the cause of gastroparesis in children is similar to that in adults, no guidelines exist for treating pediatric gastroparesis as studies on the topic are limited. With what little information we have on pediatric gastroparesis, medications used in children's studies do not seem to demonstrate the same results as in adult patients with gastroparesis; thus, future studies of whether certain medications are effective for treating pediatric gastroparesis and at what dose still need to be conducted. Pharmacological treatment options for pediatric gastroparesis do not show a clear correlation of resolving or even maintaining gastroparesis-associated symptoms or disease state. This article reviews the available studies of drugs that have shown some efficacy, with an emphasis on pediatric studies.

Basic Neuro-Optometric Diagnostic Tests for Mild Traumatic Brain Injury/Concussion: A Narrative Review, Perspective, Proposed Techniques and Protocols

2018 ◽  
pp. 157-169
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Diagnostic Test ◽  
Mild Traumatic Brain Injury ◽  
Diagnostic Tests ◽  
Test Battery ◽  
Narrative Review ◽  
Diagnostic Process ◽  
Clinical Tests ◽  
Scientific Rationale

Vision problems are common in individuals with mild traumatic brain injury (mTBI)/concussion. However, a global conceptualization of the diagnostic process remains incomplete and practitioner dependent. Thus, a comprehensive diagnostic test battery is proposed to assist in the management of these patients. This battery includes a range of basic clinical tests of a sensory and motor nature, with all having a clinical and scientific rationale. These tests have been used by the authors for many years, with good success, and furthermore they have been found to be clinically useful and insightful.

Sign in / Sign up

Export Citation Format

Share Document