Background: This study aims to determine the concentration of serum haptoglobin (Hp), interleukin 1 (IL-1β), interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α) in cases of Pneumonia, Pneumoenteritis and Enteritis.
Methods: 60 calves were subjected to the study and they were divided into four groups. The study group consisted of the claves diagnosed with clinical pneumonia (Group P; n=15), pneumoenteritis (Group PE; n=15) and enteritis (Group E; n=15) while the control group included the healthy calves (Group C; n=15). The measurements of the concentration of serum haptoglobin (Hp), interleukin 1 (IL-1β), interleukin 6 (IL-6) and tumor necrosis factor-α (TNF-α), Total protein (TP) and Albumin (ALB) were made by using commercial kits.
Conclusion: In all infection groups (P, PE ve E), Haptoglobin concentration, serum cytokine (IL-1β, IL-6 and TNF-α) and Albumin values were found to have been higher than the control group (p≤0,005). However, there was no difference in total protein. In the light of these findings, it is suggested that routine controls for Haptoglobin and cytokine (IL-1β, IL-6 and TNF-α) concentrations would be rewarding to determine the severity of the infection, to choose the suitable treatment and to detect subclinical infections in veterinary medicine.
Expression of interleukin-1 (IL-1), IL-6, and tumor necrosis factor-α (TNF-α) in non-small cell lung cancer and its relationship with the occurrence and prognosis of cancer pain