scholarly journals Psychosocial Factors and Preterm Birth Among African American and White Women in Central North Carolina

2004 ◽  
Vol 94 (8) ◽  
pp. 1358-1365 ◽  
Author(s):  
Nancy Dole ◽  
David A. Savitz ◽  
Anna Maria Siega-Riz ◽  
Irva Hertz-Picciotto ◽  
Michael J. McMahon ◽  
...  
Keyword(s):  
North Carolina ◽  
African American ◽  
Preterm Birth ◽  
Psychosocial Factors ◽  
White Women

204 Psychosocial factors and preterm birth among African-American and white women in Central North Carolina

2001 ◽  
Vol 185 (6) ◽  
pp. S137
Author(s):  
Nancy Dole ◽  
David Savitz ◽  
Anna Siega-Riz ◽  
Michael McMahon ◽  
Barbara Eucker ◽  
...  
Keyword(s):  
North Carolina ◽  
African American ◽  
Preterm Birth ◽  
Psychosocial Factors ◽  
White Women

Methodologic Considerations for Epigenomic Investigation of Preterm Birth in African American Women

2021 ◽  
pp. 019394592110303
Author(s):  
Alexandra L. Nowak ◽  
Carmen Giurgescu ◽  
Jodi L. Ford ◽  
Amy Mackos ◽  
Joyce Ohm ◽  
...  
Keyword(s):  
African American ◽  
Preterm Birth ◽  
Health Outcomes ◽  
African American Women ◽  
White Women ◽  
Therapeutic Interventions ◽  
Ethical Considerations ◽  
American Women ◽  
Adverse Health ◽  
Adverse Health Outcomes

Epigenetic modifications are chemical changes that can modify gene expression without changing the sequence of the gene. These modifications are potentially identifiable and reversible, making the epigenome an important area of research for discovering biomarkers to identify those who may be at risk and providing therapeutic interventions to prevent adverse health outcomes. African Americans bear a disproportionate risk of adverse health outcomes (e.g., hypertension, cancer). Indeed, African American women experience preterm birth (PTB; <37 completed weeks gestation) at more than twice the rate of non-Hispanic White women. Research suggests that environmental influences may play a significant role in PTB outcomes for this population. However, the biological pathways by which these influences contribute to PTB are poorly understood. This paper describes research methods and ethical considerations for the collection and analysis of biological samples based on our study examining the epigenetic regulation of stress pathways in PTB in pregnant African American women.

Relationships among psychosocial factors, biomarkers, preeclampsia, and preterm birth in African American women: A pilot

2015 ◽  
Vol 28 (1) ◽  
pp. e1-e6 ◽  
Author(s):  
Carmen Giurgescu ◽  
Natthananporn Sanguanklin ◽  
Christopher G. Engeland ◽  
Rosemary C. White-Traut ◽  
Chang Park ◽  
...  
Keyword(s):  
African American ◽  
Preterm Birth ◽  
African American Women ◽  
Psychosocial Factors ◽  
American Women

Neighborhoods, Racism, Stress, and Preterm Birth Among African American Women: A Review

2021 ◽  
pp. 019394592110411
Author(s):  
Giurgescu C. ◽  
Misra D.P. ◽  
Slaughter-Acey J.C. ◽  
Gillespie S.L. ◽  
Nowak A.L. ◽  
...  
Keyword(s):  
African American ◽  
Preterm Birth ◽  
African American Women ◽  
Social Determinants Of Health ◽  
Racial Discrimination ◽  
Social Determinants ◽  
White Women ◽  
Determinants Of Health ◽  
American Women ◽  
Vacant Housing

African American women are more likely to experience preterm birth (<37 completed weeks gestation) compared with White women. African American women are also more likely to live in neighborhoods characterized as disadvantaged (i.e., exhibiting higher rates of vacant housing, poorer property conditions, and more litter and crime) and to experience racial discrimination compared with White women. These chronic stressors have been related to preterm birth (PTB) among African American women. This review focuses on potential stress-related pathways by which neighborhood disadvantage and racial discrimination increase the risk for PTB among African American women. Specifically, we propose cortisol, systemic inflammation, proteome and lipidome profiles, and telomere shortening as potential mediators linking these social determinants of health with PTB among African American women. Examination of these factors and the signaling pathways they contribute to will increase our knowledge of the effects of social determinants of health on PTB for African American women.

Smoking and Pregnancy Outcome among African-American and White Women in Central North Carolina

Epidemiology ◽  
2001 ◽  
Vol 12 (6) ◽  
pp. 636-642 ◽  
Author(s):  
David A. Savitz ◽  
Nancy Dole ◽  
James W. Terry ◽  
Haibo Zhou ◽  
John M. Thorp
Keyword(s):  
North Carolina ◽  
African American ◽  
Pregnancy Outcome ◽  
White Women

A Tale Of Two Medicaid Cities: Community And Psychosocial Factors In Birth Outcomes Among African American And Latina Women

2002 ◽  
Author(s):  
AnnJanette Alejano-Steele ◽  
Kimberly Forrest ◽  
Grizel Gonzalez ◽  
Karen Hellman ◽  
Linda Hoctor ◽  
...  
Keyword(s):  
African American ◽  
Psychosocial Factors ◽  
Birth Outcomes ◽  
Latina Women
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