scholarly journals Development of HIGH-INTENSITY FOCUSED ULTRASOUND(HIFU) Therapy in Inferior Turbinate Hypertrophy

2021 ◽  
Author(s):  
Joon Kon Kim ◽  
Sung-Woo Cho ◽  
Hyojin Kim ◽  
Sung Chan Jo ◽  
Hyung Gu Kim ◽  
...  
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
Inferior Turbinate ◽  
High Intensity Focused Ultrasound ◽  
Cross Sectional ◽  
Histological Changes ◽  
Turbinate Hypertrophy ◽  
Mucosal Thickness ◽  
Inferior Turbinate Hypertrophy ◽  
And Control

ObjectivesInferior turbinate (IT) hypertrophy is the main cause of chronic nasal obstruction. We developed a high-intensity focused ultrasound (HIFU) ablation device to treat patients with IT hypertrophy. MethodsFirst, computed tomography (CT) images of patients without any evidence of sinonasal disease were evaluated to measure and compared the IT, medial mucosal thickness (MT), and space between the nasal septum and IT according to clinical characteristics such as septal deviation. A HIFU prototype was developed based on human anatomical studies. The experimental study was performed in five pigs; the cross-sectional areas of the nasal cavity airway and histological changes at 1 and 4 weeks postoperatively were evaluated to compare the efficacy of HIFU turbinoplasty with that of radiofrequency turbinoplasty and control. ResultsThe mean medial MT of the anterior, middle, and posterior portions of the IT were 4.66

scholarly journals Nasal septal angle deviation: effect on lateral wall in nasal obstruction

2018 ◽  
Vol 7 (1) ◽  
pp. 90
Author(s):  
Neha Bagri ◽  
Kavirajan K. ◽  
Ranjan Chandra ◽  
Yatish Agarwal ◽  
Neetika Gupta ◽  
...  
Keyword(s):  
Ct Scan ◽  
Nasal Obstruction ◽  
Inferior Turbinate ◽  
Septal Deviation ◽  
P Value ◽  
Lateral Nasal Wall ◽  
Nasal Breathing ◽  
Cross Sectional ◽  
Turbinate Hypertrophy ◽  
Inferior Turbinate Hypertrophy

Background: Deviation of the nasal septum (DNS) refers to the convexity of the septum to one side disturbing the nasal physiology with obstructed nasal breathing leading to lateral nasal wall abnormalities and paranasal sinuses (PNS) mucosal disease. Knowledge of nasal morphological parameters plays an important role in planning successful nasal surgery. Our aim was to evaluate the angle of septal deviation (ASD) on CT scan and study its influence on the lateral nasal wall abnormalities and PNS mucosal disease.Methods: A prospective cross-sectional observational study was conducted on 130 patients with clinical evidence of DNS and chronic sinusitis. The direction and severity of DNS was recorded on CT scan along with evaluation of lateral nasal wall and sinus mucosal abnormalities.Results: Increasing ASD had statistically significant correlation with the lateral nasal wall abnormalities, most commonly, contralateral middle and inferior turbinate hypertrophy (p-value <0.0001). No significant association was found with the incidence of ipsilateral or contralateral osteomeatal complex (OMC) obstruction and sinus mucosal disease.Conclusions: The direction and severity of septal deviation has significant impact on contralateral middle and inferior turbinate hypertrophy. The analysis of these ancillary pathologies can be of great help to the surgeon in better management of patients with nasal obstruction.

Inspiratory and Fixed Nasal Valve Collapse: Clinical and Rhinometric Assessment

2005 ◽  
Vol 19 (4) ◽  
pp. 370-374 ◽  
Author(s):  
Ramakrishnan Vidyasagar ◽  
Michael Friedman ◽  
Hani Ibrahim ◽  
Darius Bliznikas ◽  
Ninos J. Joseph
Keyword(s):  
Inferior Turbinate ◽  
Nasal Valve ◽  
Dual Mode ◽  
Cross Sectional ◽  
Turbinate Hypertrophy ◽  
Number Of Patients ◽  
Inferior Turbinate Hypertrophy ◽  
Nasal Valve Collapse ◽  
External Nasal Valve ◽  
Valve Area

Background Acoustic rhinometry (AR) has been used to assess nasal valve obstruction. Standard AR measurement of the cross-sectional area (CSA) of the nasal valve is done in the apneic phase, whereas collapse often occurs on inspiration. We used the ratio of the CSA obtained during active inspiration and during apnea to compute a more meaningful method of diagnosing nasal valve collapse. Methods AR was performed in 40 patients without nasal valve obstruction and 47 patients diagnosed with nasal valve obstruction. Patients with septal deflection or anterior inferior turbinate hypertrophy were excluded. The internal and external nasal valve area was observed during apnea and on active inspiration. AR measurement of the CSA of both nasal valves was performed during the apneic phase and during active inspiration and the CSA (inspiratory)/CSA (apneic) ratio was calculated. Results The CSA (inspiratory)/CSA (apneic) ratio was ≥1 in normal patients and in patients with fixed nasal valve collapse. The ratio was <1 in patients with inspiratory collapse. Data from history, physical examination, and dual-mode AR testing successfully differentiated patients into (1) normal valves, (2) fixed valve collapse, and (3) inspiratory valve collapse. A large number of patients with collapse had both internal and external valve obstruction and a large number also had a combination of inspiratory and fixed collapse. Conclusion Dual-mode AR testing is an effective tool in more precisely identifying nasal valve obstruction and is the first objective test shown to be highly diagnostic of inspiratory nasal valve collapse.

scholarly journals Histological changes in the human prostate after radiotherapy and salvage high intensity focused ultrasound

2013 ◽  
Vol 4 (4) ◽  
pp. 100 ◽  
Author(s):  
Venu Chalasani ◽  
Carlos H. Martinez ◽  
Andrew K. Williams ◽  
Kevin Kwan ◽  
Joseph L. Chin
Keyword(s):  
Conservative Management ◽  
High Intensity ◽  
Focused Ultrasound ◽  
External Beam Radiotherapy ◽  
Specific Antigen ◽  
High Intensity Focused Ultrasound ◽  
External Beam ◽  
Histological Changes ◽  
Salvage Hifu ◽  
Symptoms And Signs

The histological changes (both macroscopic and microscopic) in theprostate following the combination of external beam radiotherapyand salvage high intensity focused ultrasound (HIFU) have notbeen previously described. This article describes the case of a65-year-old male who presented with recurrent localized prostatecancer after undergoing external beam radiotherapy for low-riskprostate cancer. He was treated with salvage HIFU, and 4 weekslater presented with symptoms and signs consistent with a prostatorectalfistula. During a period of conservative management, hisserum prostate-specific antigen levels started rising after havingreached a nadir. A radical cystoprostatectomy and repair of fistulawere performed after conservative management failed. Histologicalchanges of dense fibrosis were noted in the region where theprostate should have been located. A literature review of thehistological findings in the prostate after HIFU is discussed in thisarticle, as well as the available evidence for the management ofpatients with local failure after the combination of external beamradiotherapy and salvage HIFU.

Septoplasty and compensatory inferior turbinate hypertrophy: a randomized study evaluated by acoustic rhinometry

1993 ◽  
Vol 107 (5) ◽  
pp. 413-417 ◽  
Author(s):  
L. F. Grymer ◽  
P. Illum ◽  
O. Hilberg
Keyword(s):  
Randomized Study ◽  
Inferior Turbinate ◽  
Cross Sectional Area ◽  
Septal Deviation ◽  
Acoustic Rhinometry ◽  
Sectional Area ◽  
Cross Sectional ◽  
Turbinate Hypertrophy ◽  
Inferior Turbinate Hypertrophy ◽  
Turbinate Reduction

The present study deals with the indication for inferior turbinate surgery in cases of concomitant anterior septal deviation. We define, by acoustic rhinometry, the characteristics of the obstructed nose and define mucosal turbinate hypertrophy. A random sample of 80 patients with nasal obstruction and anteriorly located septal deviation were objectively evaluated by acoustic rhinometry pre– and post–operatively. All had septoplasty and half were randomly selected to have anterior inferior turbinoplasty performed in the side opposite to the major septal deviation. Severe septal deviation, expressed by a minimal cross–sectional area less than 0.4 cm2 was present in 37 patients. In this group inferior turbinate reduction seems advisable. In the wide side, the minimal cross–sectional area and the cross–sectional areas at 3.3 and 4.0 cm from the nostrils increased in the turbinectomy group and decreased in the non–turbinectomy group after correction of the septal deviation. In the group with less pronounced septal deviation no influence of turbinate reduction could be detected.

scholarly journals Dynamics and control of cavitation during high-intensity focused ultrasound application

2005 ◽  
Vol 6 (3) ◽  
pp. 182-187 ◽  
Author(s):  
Charles R. Thomas ◽  
Caleb H. Farny ◽  
Constantin C. Coussios ◽  
Ronald A. Roy ◽  
R. Glynn Holt
Keyword(s):  
High Intensity ◽  
Focused Ultrasound ◽  
High Intensity Focused Ultrasound ◽  
Dynamics And Control ◽  
Ultrasound Application ◽  
And Control

scholarly journals Diode Laser Turbinate Reduction in Allergic Rhinitis: A Cross-sectional Study

2018 ◽  
Vol 56 (214) ◽  
pp. 949-952
Author(s):  
Priyanka Gupta ◽  
Toran Kc ◽  
Deepak Regmi
Keyword(s):  
Allergic Rhinitis ◽  
Diode Laser ◽  
Medical Therapy ◽  
Inferior Turbinate ◽  
Cross Sectional Study ◽  
Nasal Discharge ◽  
Cross Sectional ◽  
Turbinate Hypertrophy ◽  
Inferior Turbinate Hypertrophy ◽  
Turbinate Reduction

Introduction: Turbinate reduction procedures are recommended for inferior turbinate hypertrophy in allergic rhinitis that fail to respond to medical therapy. Several modalities like turbinectomy, submucosal resection and tissue ablation are available for this purpose. The study aimed to evaluate the effectiveness of diode laser in the treatment of symptomatic inferior turbinate hypertrophy in allergic rhinitis and explore complications related to the procedure.Methods: This descriptive cross-sectional study was carried out in a tertiary care centre. The study enrolled 60 patients with inferior turbinate hypertrophy with failure of medical therapy. Inferior turbinate reduction was performed under local anaesthesia using diode laser. All the patients were evaluated subjectively for various nasal symptoms using visual analogue score scale preoperatively and during postoperative visit at three months.Results: The age ranged from 16 to 47 years with median age of 28 years. Twenty nine were male and thirty one were female. There was significant improvement in symptoms like nasal obstruction, nasal discharge, sneezing and decreased sense of smell. Immediate post-operative pain, crusting and persistent nasal discharge were observed as complications of the procedure. However, there was no incidence of mucosal oedema and synechiae formation in our study.Conclusions: Diode laser turbinate reduction procedure is safe, minimally invasive and effective in relieving the symptoms associated with inferior turbinate hypertrophy in allergic rhinitis resistant to medical therapy and can be performed on a day care basis under local anaesthesia.

Sign in / Sign up

Export Citation Format

Share Document