High-Intensity Focused Ultrasound Leads to Histopathologic Changes of the Inferior Turbinate Mucosa with Allergic Inflammation

ObjectivesInferior turbinate (IT) hypertrophy is the main cause of chronic nasal obstruction. We developed a high-intensity focused ultrasound (HIFU) ablation device to treat patients with IT hypertrophy. MethodsFirst, computed tomography (CT) images of patients without any evidence of sinonasal disease were evaluated to measure and compared the IT, medial mucosal thickness (MT), and space between the nasal septum and IT according to clinical characteristics such as septal deviation. A HIFU prototype was developed based on human anatomical studies. The experimental study was performed in five pigs; the cross-sectional areas of the nasal cavity airway and histological changes at 1 and 4 weeks postoperatively were evaluated to compare the efficacy of HIFU turbinoplasty with that of radiofrequency turbinoplasty and control. ResultsThe mean medial MT of the anterior, middle, and posterior portions of the IT were 4.66

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260: High Intensity Focused Ultrasound Combined with Endocrine Therapy in Treating High or Intermediate Risk Prostate Cancer

The Journal of Urology ◽

10.1016/s0022-5347(18)32527-8 ◽

2006 ◽

Vol 175 (4S) ◽

pp. 86-86

Author(s):

Makoto Sumitomo ◽

Junichi Asakuma ◽

Yasumasa Hanawa ◽

Kazuhiko Nagakura ◽

Masamichi Hayakawa

Keyword(s):

Prostate Cancer ◽

Endocrine Therapy ◽

High Intensity ◽

Focused Ultrasound ◽

High Intensity Focused Ultrasound ◽

Intermediate Risk ◽

Risk Prostate Cancer

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1400: Early Clinical Experience Using High-Intensity Focused Ultrasound for the Treatment of Renal Tumours

The Journal of Urology ◽

10.1016/s0022-5347(18)35534-4 ◽

2005 ◽

Vol 173 (4S) ◽

pp. 379-380

Author(s):

James E. Kennedy ◽

Rowland O. Illing ◽

Feng Wu ◽

Gail R. ter Haar ◽

Rachel R. Phillips ◽

...

Keyword(s):

Clinical Experience ◽

High Intensity ◽

Focused Ultrasound ◽

High Intensity Focused Ultrasound ◽

Early Clinical Experience ◽

Renal Tumours

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High-Intensity Focused Ultrasound

Gastrointestinal Endoscopy Clinics of North America ◽

10.1016/s1052-5157(18)30511-7 ◽

1994 ◽

Vol 4 (2) ◽

pp. 383-395 ◽

Cited By ~ 32

Author(s):

Narendra T. Sanghvi ◽

Robert H. Hawes

Keyword(s):

High Intensity ◽

Focused Ultrasound ◽

High Intensity Focused Ultrasound

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Abstract #593 High Intensity Focused Ultrasound (HIFU) in the Treatment of Thyroid Nodules. Efficacy, Side-Effects and Predictive Factors of Clinical Outcome

Endocrine Practice ◽

10.1016/s1530-891x(20)46937-x ◽

2019 ◽

Vol 25 ◽

pp. 304-305

Author(s):

Enrico Papini ◽

Agnese Persichetti ◽

Antonio Bianchini ◽

Carmela Coccaro ◽

Marco Chianelli ◽

...

Keyword(s):

Side Effects ◽

Clinical Outcome ◽

Predictive Factors ◽

High Intensity ◽

Focused Ultrasound ◽

Thyroid Nodules ◽

High Intensity Focused Ultrasound

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Das Prostatakarzinom: aktuelle Diagnostik und Therapiestandard

Praxis ◽

10.1024/1661-8157/a002437 ◽

2016 ◽

Vol 105 (16) ◽

pp. 971-977

Author(s):

Jan Brachlow ◽

Martin Kälin ◽

Marco Randazzo ◽

Beat Förster ◽

Hubert John

Keyword(s):

High Intensity ◽

Focused Ultrasound ◽

High Intensity Focused Ultrasound ◽

Psa Test ◽

Eine Hohe ◽

Psa Screening ◽

Sekundäre Hormontherapie

Zusammenfassung. Das Prostatakarzinom zeigt eine hohe Prävalenz und ist daher für die behandelnden Ärzte medizinisch, aber auch gesundheitspolitisch relevant. PSA-Screening senkt die karzinomspezifische Mortalität, ist jedoch aufgrund der hohen Prävalenz mit einer Überdiagnostik verbunden. Dies fordert im Gegenzug einen verantwortungsbewussten Umgang mit dem PSA-Test («smarter screening»). Durch die robotergestützte Prostatektomie steht eine Therapie mit geringer Morbidität zur Behandlung des lokalisierten Prostatakarzinoms zur Verfügung. Das fokale Behandlungskonzept der HIFU (high-intensity focused ultrasound) ist vielversprechend, jedoch noch klinisch experimentell und sollte im Rahmen von Studien angeboten werden. Die Behandlungsmöglichkeiten beim metastasierten Prostatakarzinom wurden entscheidend vervielfältigt. Chemotherapie und die sekundäre Hormontherapie werden voraussichtlich vermehrt in früheren Phasen der Krankheit eine Rolle spielen, wodurch die Therapie für den einzelnen Patienten immer komplexer wird und individuell angepasst werden muss.

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