scholarly journals FREE RADICAL SCAVENGING ACTIVITY OF SIX MEDICINAL PLANTS OF BANGLADESH: A POTENTIAL SOURCE OF NATURAL ANTIOXIDANT

2015 ◽  
Vol 7 ◽  
pp. 78
Author(s):  
Shakhawat Hossain ◽  
Keyword(s):  
Free Radical ◽  
Medicinal Plants ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Moderate Activity ◽  
Potential Source ◽  
Anti Oxidant ◽  
Free Radical Scavenging Assay

The crude meoh extracts of six medicinal plants of bangladesh (ipomoea paniculata, withaniasomnifera, mikaniacordata, abromaaugusta, bombaxceiba, and oxalis corniculata) were screened for primary types of phytochemicals presence and in-vitro anti-oxidant activity by using the 1,1-diphenyl-2-picryldydrazyl-hydrate (dpph) free radical scavenging assay. Of all of them, the meoh extracts of the leaves of withaniasomnifera and oxalis corniculata showed strong antioxidant activity (ic50:27.8 and 19.98ï­g/ml), while the meoh extracts of ipomoea paniculata, abromaaugusta and bombaxceiba showed moderate activity (ic50: 86.48, 101.4 and 58.6 ï­g/ml, respectively).

scholarly journals Assessment of anti-oxidant activity of Ficus benghalensis leaves: an In-vitro design

2019 ◽  
Vol 9 (2) ◽  
pp. 20-24
Author(s):  
Aditi Pedgaonkar ◽  
Gadeela Manish Adithya ◽  
Panyala Sandhya Reddy ◽  
Kollu Thanuja ◽  
Lankadasari Divyashree ◽  
...  
Keyword(s):  
Free Radical ◽  
Methanolic Extract ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Scavenging Activity ◽  
Ficus Benghalensis ◽  
Anti Oxidant ◽  
Free Radical Scavenging Assay ◽  
Radical Scavenging Assay

Background: Medicinal plants represent a rich source of natural anti-oxidants. The traditional medicine involves the use of different plant extracts of bioactive constituents. Ficus benghalensis is a large evergreen tree found throughout India. It is commonly called Banyan tree. It is used in traditional system of medicine like Ayurveda and homoeopathy. Ficus is a huge tropical deciduous or evergreen tree with more than 800 species. Objective: Anti-oxidant effect of ethnomedicinal important plant species Ficus benghalensis (Family-Moraceae) was screened. The aim of this study was to assess the in-vitro potential of methanolic extract of Ficus benghalensis leaves as a natural anti-oxidant. Method: Assessment of in vitro anti-oxidant activity of methanolic leaves extract of Ficus benghalensis was determined by DPPH free radical scavenging assay. Results: The methanolic extract of Ficus benghalensis leaves demonstrates a remarkable amount of phenolic content (54 μg/ml of GAE/100gm of extract) by using Folin-ciocalteu reagent. In-vitro anti-oxidant activity of methanolic leaves extract of Ficus benghalensis was determined by DPPH free radical scavenging assay, which showed significant anti-oxidant activity compared to standard anti-oxidant (ascorbic acid). A direct correlation between total phenol and anti-oxidant activity indicates polyphenols are the main anti-oxidants. Conclusion: These findings suggest the excellent medicinal bio-activity of Ficus benghalensis and explain the popularity of this plant in the folk medicine as a remedy for different disorders, thus supporting its folklore application as preventive remedy as an anti-oxidant. The present study shows that Ficus benghalensis leaves have radical scavenging activity and can be considered as good sources of natural anti-oxidants for medicinal and commercial uses. Keywords: Ficus benghalensis, anti-oxidant, DPPH scavenging activity, Folin-ciocalteu reagent.

scholarly journals In Vitro Hypoglycemic and Radical Scavenging Activities of Certain Medicinal Plants

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Thanh Sang Vo ◽  
Phuong Uyen Le ◽  
Dai-Hung Ngo
Keyword(s):  
Free Radical ◽  
Medicinal Plants ◽  
Glucose Uptake ◽  
Amylase Activity ◽  
Cell Model ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Alpha Amylase

AbstractThe purpose of this study is to investigate in vitro hypoglycemic and free radical scavenging activities of some medicinal plants including Ficus glomerata (FG), Pandanus amaryllifolia (PaA), Artocarpus altilis (AA), Gomphrena celosioides (GC) and Gynostemma pentaphyllum (GP). Alpha-amylase inhibitory assay was examined by dinitrosalicylic acid reaction. Glucose up-take assay was investigated by LO-2 cell model. DPPH and ABTS+ scavenging assays were performed by spectrophotometry. Cell viability was determined by MTT method. It was found that the extracts including FG, PaA, AA, GC and GP were able to inhibit alpha-amylase activity up to 38.4 ± 4.2%, 47.8 ± 4.3%, 49.3 ± 3.5%, 40.1 ± 4.4% and 38.5 ± 3.8%, respectively. Moreover, glucose adsorption and glucose uptake capacity of these extracts were evidenced. In addition, free radical scavenging activity of these extracts was indicated in a range of 30.6-54.5% for DPPH radical and 31.8-51.1% for ABTS+ radical. Especially, these extracts exhibited no cytotoxicity effect on human hepatic LO-2 cells and human gastric BGC-823 cells at the concentration of 100 µg/ml. The results indicated that A. altilis leaves were effective in inhibiting alpha-amylase activity, increasing glucose adsorption and glucose uptake and scavenging free radicals. Therefore, it could be suggested to be a promising hypoglycemic agent for managing type 2 diabetes.

scholarly journals Phytochemical screening and In-vitro antioxidant activity of Centella asiatica extracts

2017 ◽  
Vol 9 (4) ◽  
pp. 615
Author(s):  
Mukesh Kumar Yadav ◽  
Santosh Kumar Singh ◽  
JS Tripathi ◽  
YB Tripathi
Keyword(s):  
Hydrogen Peroxide ◽  
Antioxidant Activity ◽  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Centella Asiatica ◽  
Free Radical Scavenging ◽  
Scavenging Activity ◽  
Phytochemical Screening

<p><em>Centella asiatica</em> also known as <em>mandukparni </em>or Indian pennywort or <em>jalbrahmi</em>, which has been used as a medicine in the Ayurveda from ancient times and mentioned in many classical texts of Ayurveda. <em>Centella asiatica</em> has long been used to improve memory and cognitive function.</p><p>The study aimed to identify the phytochemicals present in different solvent extracts of <em>Centella asiatica </em>(i.e. PECA- Petroleum ether extract of <em>C. asiatica, </em>CCA- Chloroform extract of <em>C. asiatica, </em>EACA- Ethyl acetate extract of <em>C. asiatica,</em> ECA- Ethanolic extract of <em>C. asiatica, </em>HACA- Hydro-alcoholic extract of <em>C. asiatica</em>)<em> </em>and evaluate the respective in-vitro antioxidant potentials. <em></em></p><p>The phytochemical screening of extracts was done with standardized procedures and the antioxidant potential of different solvent extracts of <em>Centella asiatica</em> was assessed by its free radical scavenging activity 2, 2-diphenyl -1- picrylhydrazyl (DPPH) as well as hydrogen peroxide scavenging assay respectively for reducing capability.</p><p>In all different solvent extracts of <em>C. asiatica</em> revealed excellent free radical scavenging activity as revealed by 2-2- diphenyl-1-picryl-hydrazyl (DPPH) assay with  EC<sub>50</sub> values for ECA=128.752±1.85 μg/ml, HACA=274.884±1.21 μg/ml and hydrogen peroxide assay against the standard (Butylated hydroxytoluene) BHT, with the EC<sub>50</sub> values ECA=429.69±0.92 μg/ml HACA=458.08±0.58 μg/ml while rest solvent extracts shown very less antioxidant activity.</p><p> The present study indicates that the <em>Centella asiatica</em> extracts have good antioxidant activity which can be used in stress and anxiety and also a good source to be used as natural drugs.</p>

The Assessment of the Free Radical Scavenging Activity and Flavonoid Contents of Selected Medicinal Plants of Mizoram

2020 ◽  
Vol 15 (1) ◽  
pp. 34-43
Author(s):  
Alex Zohmachhuana ◽  
Malsawmdawngliana Malsawmdawngliana M ◽  
Lalrinzuali K Lalrinzuali ◽  
Lalnunmawia F Lalnunmawia ◽  
Vabeiryureilai M Vabeiryureilai ◽  
...  
Keyword(s):  
Free Radical ◽  
Medicinal Plants ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Scavenging Activity
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