scholarly journals Drug Induced Pure White Cell Aplasia: A Case Report and Review of Literature

2017 ◽  
Vol 2 (2) ◽  
pp. 88-91
Author(s):  
Aisha Jamal ◽  
Uzma Zaidi ◽  
Jawad Hasan Kazmi ◽  
Munira Borhany ◽  
Quratulain Rizvi ◽  
...  
2020 ◽  
Vol 11 (02) ◽  
pp. 349-352
Author(s):  
Rajeev Sharma ◽  
Prasenjit Das ◽  
Arvind Kairo ◽  
Shashank S. Kale

AbstractDrug-induced gingival overgrowth (DIGO) secondary to chronic phenytoin intake for seizure control is a well-recognized phenomenon. Phenytoin-induced gingival overgrowth (PIGO) usually resolves gradually following cessation of phenytoin intake. It is usually seen throughout the dentate regions of the maxillary and mandibular dental arches, but more severely affect their anterior portions exposed to atmosphere. We report a rare case of PIGO predominantly involving hard palate and floor of oral cavity, which has not been reported in English literature till date.


2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Peter Geon Kim ◽  
Joome Suh ◽  
Max W. Adelman ◽  
Kwadwo Oduro ◽  
Erik Williams ◽  
...  

Pure white cell aplasia (PWCA) is a rare hematologic disorder characterized by the absence of neutrophil lineages in the bone marrow with intact megakaryopoiesis and erythropoiesis. PWCA has been associated with autoimmune, drug-induced, and viral exposures. Here, we report a case of a 74-year-old female who presented with severe proximal weakness without pain and was found to have PWCA with nonspecific inflammatory necrotizing myositis and acute liver injury on biopsies. These findings were associated with a recent course of azithromycin and her daily use of a statin. Myositis improved on prednisone but PWCA persisted. With intravenous immunoglobulin and granulocyte-colony stimulating factor therapies, her symptoms and neutrophil counts improved and were sustained for months.


2012 ◽  
Vol 107 ◽  
pp. S191
Author(s):  
Siddharth Bansal ◽  
Alexander Mallari ◽  
Radu Serban ◽  
Jason Gutman ◽  
Joel McFarland

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Eduardo A. Rodriguez ◽  
Raquel Teixeira Yokoda ◽  
David E. Payton ◽  
Rish Pai ◽  
Thomas J. Byrne

Drug induced liver injury is a very frequent cause of hepatotoxicity and within that group, herbal and dietary supplements are a well described subcategory. The following clinical vignette describes the case of a young man with acute hepatitis secondary to the use of Ilex paraguariensis, also known as yerba mate, which is a herbal product commonly drunk in South America. This is the first written case of mate tea induced hepatotoxicity.


2014 ◽  
Vol 2 (5) ◽  
pp. 34 ◽  
Author(s):  
Ahmed Zedan ◽  
Sabry Omar ◽  
Mahmoud Fenire

Drugs, including those used during diagnostic procedures, can have adverse effects and potentially serious side-effects, especially in complicated patients with significant comorbidity. Benzocaine is frequently used as an oropharyngeal anesthetic agent during bronchoscopy, transesophageal echocardiography, and upper GI endoscopy and can cause methemoglobinemia, a potentially life-threatening event if not diagnosed and treated quickly. Co-oximetry is the gold standard for the diagnosis of methemoglobinemia and can quantitate blood levels, which in turn correlate with the clinical presentation and the urgency for treatment. Methylene blue is the treatment of choice for methemoglobinemia. In this case report we discuss the pathophysiology, the clinical presentation, the diagnosis, and the treatment of benzocaine-induced methemoglobinemia.


2014 ◽  
Vol 34 (3) ◽  
pp. 283-288 ◽  
Author(s):  
K. Akinosoglou ◽  
M. Melachrinou ◽  
D. Siagris ◽  
E. Koletsis ◽  
M. Marangos ◽  
...  

2020 ◽  
Vol 5 (1) ◽  
pp. p27
Author(s):  
Hamzeh Mohammad Alrawashdeh, MD ◽  
Yazan Abu Gharbieh, MD ◽  
Omar Khalil Hamdan, MD ◽  
Mohammed Farah, MD

A very little subset of patients diagnosed with interstitial nephritis have the tubulointerstitial nephritis and uveitis (TINU syndrome). A considerable number of cases have been documented in the pediatric nephrology and ophthalmology literature. We report a 12-year-old girl who presented with a history of allergic/drug-induced tubulointerstitial nephritis and diagnosed months later to have uveitis after stopping steroids. This considered a very rare combination and the diagnosis of tubulointerstitial nephritis and uveitis syndrome was established. She was treated successfully with topical steroid and topical cycloplegic agent for about 7 weeks. About 250 cases have been reported worldwide, and this is the first reported case in Jordan.


2006 ◽  
Vol 3 (1) ◽  
pp. 55-57 ◽  
Author(s):  
S Dwarakanath ◽  
S Gopal ◽  
R Satish ◽  
NK Venkataramana

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