Since mudstone interlayer has a big influence on the mechanic property of layered rock salt, and in order to research its law, the mudstone which strength is lower than pure rock is used as a interlayer to make the regular layer of salt formation, then both the uniaxial and triaxial compression test are carried out on the layer of salt formation. The result indicates: (1) As the thickness of interlayer increases the uniaxial compressive strength and elastic modulus of layer type salt decrease. (2) On the condition that the thickness of interlayer does not change, the more the interlayer number, the stronger the uniaxial compressive strength. (3) If the total thickness of interlayer is stable and the interlayer number is same, then as the distance of interlayer increases the uniaxial compressive strength and elastic modulus of layer type salt decrease. The result provides practical value and theoretic basis on the further research of the mechanic property of layered rock soil and on the analysis of the stability of Karst underground salt cavity reservoir.