scholarly journals A Conjugated Polymer Fluorescent Sensor for Continuous Identification of Copper(II) and Pyrophosphate in Blood Serum and Synovial Fluid

2019 ◽  
Vol 35 (6) ◽  
pp. 625-630 ◽  
Author(s):  
Mingming GUAN ◽  
Chunling XU ◽  
Jiahua MA ◽  
Ting YANG ◽  
Jilin LIU ◽  
...  
Keyword(s):  
Synovial Fluid ◽  
Blood Serum ◽  
Conjugated Polymer ◽  
Fluorescent Sensor

A simple and reusable fluorescent sensor for heme proteins based on a conjugated polymer-doped electrospun nanofibrous membrane

Talanta ◽  
2012 ◽  
Vol 94 ◽  
pp. 216-222 ◽  
Author(s):  
Huaming Wang ◽  
Zhou Peng ◽  
Yuanyuan Long ◽  
Haibo Chen ◽  
Yufei Yang ◽  
...  
Keyword(s):  
Conjugated Polymer ◽  
Heme Proteins ◽  
Fluorescent Sensor ◽  
Nanofibrous Membrane

Amplifying fluorescent conjugated polymer sensor for singlet oxygen detection

2019 ◽  
Vol 55 (61) ◽  
pp. 8955-8958 ◽  
Author(s):  
Chun-Han Wang ◽  
Evgueni E. Nesterov
Keyword(s):  
Singlet Oxygen ◽  
Conjugated Polymer ◽  
Energy Gap ◽  
Fluorescent Sensor ◽  
Oxygen Detection ◽  
Turn On

A “higher energy gap” concept was used to design an efficient conjugated polymer turn-on amplifying fluorescent sensor for singlet oxygen.

Preparation and application of a highly sensitive conjugated polymer-copper (Ⅱ) composite fluorescent sensor for detecting hydrazine in aqueous solution

Talanta ◽  
2020 ◽  
Vol 207 ◽  
pp. 120203 ◽  
Author(s):  
Zhiru Hu ◽  
Ting Yang ◽  
Jilin Liu ◽  
Zhiquan Zhang ◽  
Guodong Feng
Keyword(s):  
Aqueous Solution ◽  
Conjugated Polymer ◽  
Fluorescent Sensor ◽  
Highly Sensitive

Conjugated polymer-hybridized silica nanoparticle as a fluorescent sensor for cysteine

2016 ◽  
Vol 73 (9) ◽  
pp. 2447-2456 ◽  
Author(s):  
Geunseok Jang ◽  
Taek Seung Lee
Keyword(s):  
Conjugated Polymer ◽  
Fluorescent Sensor ◽  
Silica Nanoparticle

scholarly journals Comparative Analysis of the Occurrence and Role of CX3CL1 (Fractalkine) and Its Receptor CX3CR1 in Hemophilic Arthropathy and Osteoarthritis

2020 ◽  
Vol 2020 ◽  
pp. 1-12 ◽  
Author(s):  
Piotr Wojdasiewicz ◽  
Łukasz A. Poniatowski ◽  
Andrzej Kotela ◽  
Marta Skoda ◽  
Michał Pyzlak ◽  
...  
Keyword(s):  
Articular Cartilage ◽  
Synovial Fluid ◽  
Blood Serum ◽  
Synovial Membrane ◽  
Study Group ◽  
Vessel Morphology ◽  
Hemophilic Arthropathy ◽  
Significant Difference ◽  
Receptor Cx3cr1

Objective. Hemophilic arthropathy is characterized by recurrent bleeding episodes in patients with hemophilia leading to irreversible joint degeneration. The involvement of CX3CL1 (fractalkine) and its receptor CX3CR1 was observed in the pathogenesis of numerous arthritis-associated diseases. Taking this into account, we have presented a study investigating the role of the CX3CL1/CX3XR1 axis in the course of hemophilic arthropathy, including the CX3CL1-dependent expression of CD56+, CD68+, and CD31+ cells along with evaluation of articular cartilage and synovial membrane morphology. Methods. The study was carried out using cases (n=20) of end-stage hemophilic arthropathy with a severe type of hemophilia A and control cases (n=20) diagnosed with osteoarthritis. The biofluids including blood serum and synovial fluid were obtained intraoperatively for the evaluation of CX3CL1 using the ELISA test. Tissue specimens including articular cartilage and synovial membrane were similarly collected during surgery and stained immunohistologically using selected antibodies including anti-CX3CR1, anti-CD56, anti-CD68, and anti-CD31. Additionally, the analysis included the assessment of articular cartilage, synovial membrane, and blood vessel morphology. Results. In our study, we have documented increased average concentration of CX3CL1 in the blood serum of the study group (7.16±0.53 ng/ml) compared to the control group (5.85±0.70 ng/ml) without statistically significant difference in synovial fluid concentration at the same time. We have observed an increased macrophage presence with more marked proliferation and fibrosis of the synovial membrane in the study group. Remaining results such as expression of CX3CR1 presence of NK cells and larger surface area of blood vessels within the synovial membrane were noted also without statistical significance. Conclusions. This study has demonstrated collective CX3CL1/CX3CR1 axis involvement in hemophilic arthropathy pathogenesis introducing new interesting diagnostics and a therapeutic target.

Highly sensitive fluorescent sensor for copper (II) based on amplified fluorescence quenching of a water-soluble NIR emitting conjugated polymer

2012 ◽  
Vol 177 (3-4) ◽  
pp. 357-364 ◽  
Author(s):  
Lilin Sun ◽  
Dan Hao ◽  
Weili Shen ◽  
Zhangsheng Qian ◽  
Changqing Zhu
Keyword(s):  
Fluorescence Quenching ◽  
Conjugated Polymer ◽  
Fluorescent Sensor ◽  
Water Soluble ◽  
Highly Sensitive

Evaluation of the changes of P1NP and CTX in synovial fluid and blood serum of dogs with experimental osteoarthritis

2016 ◽  
Vol 25 (3) ◽  
pp. 559-563
Author(s):  
Behrooz Nikahval ◽  
Saeed Nazifi ◽  
Fahime Heidari ◽  
Mohamad Saeed Ahrari Khafi
Keyword(s):  
Synovial Fluid ◽  
Blood Serum ◽  
Experimental Osteoarthritis
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