scholarly journals Predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam Zone, northwest, Ethiopia, 2017

2019 ◽  
Author(s):  
Habtamu Belew Mera ◽  
Moges Wubie ◽  
Getaye Tizazu ◽  
Abebaw Bitew ◽  
Tesfa Birlew

Abstract Background: Tuberculosis is a serious health threat, especially for people living with human immune deficiency virus worldwide and the burden of TB/HIV infection is still high in Ethiopia in particular. Objective: To determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and west Gojjam, Northwest Ethiopia, 2017Methods: An institution based unmatched case-control study was conducted in East and West Gojjam Zone, Northwest, Ethiopia from March 7-April 15, 2017. Cases were 139 tuberculosis infected human immune deficiency virus positives and controls were 413 non-TB infected HIV positives i.e. 1:3 proportion. All cases in each health facility who confirmed by acid-fast bacilli (direct microscopy), culture and gene expert were considered as TB positive fine needle aspiration. However controls were selected by using simple random sampling technique through the above diagnostic criteria and the data were collected with Face to face interview as well as patient medical record were used and the quality of the data were assured, checked, coded, cleaned and entered in EPI-Data version 3.1 and exported to SPSS version 20 for the analysis. Result: Of the total sample (556), just about 552(99.2%) were participated in the study among this 47.5% were females and 58.9% were rural. Behavioral and modifiable biological risk factors: alcohol users (AOR=2.33; 95% CI:1.34,4.07), BMI<18.5kg/m2 (AOR=3.03;95%CI:1.79,5.14), CD4 count ≤200 cells/µl (AOR=2.34;95%CI:1.89,2.79) and between 201-499 cells/µl (AOR=2.63; 95%CI: 1.01,6.84), bedridden and ambulatory (AOR=3.3;95%CI:1.70,6.29 and AOR=8.2;95%CI:4.34,15.64),respectively. TB history in the family (AOR=3.00; 95%CI: 1.57, 5.74) were predictors for TB infection. Taking CPT (AOR=0.36; 95%CI: 0.21, 0.62) and having early WHO clinical stage I or II (AOR=0.34; 95%CI: 0.20, 0.56) had protective effect against TB infection. Conclusion &Recommendation: Behavioral, biological, clinical and TB history in the family were highly prevalent in the study area. Strengthen screening more frequently, CPT Prophlaxysis and treated promptly important to reduce TB co-morbidity.

2019 ◽  
Author(s):  
Habtamu Belew Mera ◽  
Moges Wubie ◽  
Getaye Tizazu ◽  
Abebaw Bitew ◽  
Tesfa Birlew

Abstract Background Tuberculosis is a serious health threat, especially for people living with human immune deficiency virus and is more likely than others to become sick with tuberculosis are. Objective Predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in Gojjam, Northwest Ethiopia, 2017 Methods An institution based unmatched case-control study was conducted in East and West Gojjam Zone, Northwest, Ethiopia from March 7-April 15, 2017. Cases were 139 tuberculosis infected human immune deficiency virus positives and controls were 413 non-TB infected HIV positives i.e. 1:3 proportion. All cases in each health facility were included. but controls were selected by using simple random sampling technique and the data were collected with Face to face interview as well as patient medical record were used and the quality of the data were assured, the data were checked, coded, cleaned and entered in EPI-Data version 3.1 and exported to SPSS version 20 for the analysis. Result of the total sample (556), just about 552(99.2%) were participated in the study (female=47.5% and rural=58.9%). Behavioral and modifiable biological risk factors: alcohol users (AOR=2.33; 95% CI:1.34,4.07), BMI<18.5kg/m2 (AOR=3.03;95%CI:1.79,5.14), CD4 count ≤200 cells/µl (AOR=2.34;95%CI:1.89,2.79) and between 201-499 cells/µl (AOR=2.63; 95%CI: 1.01,6.84), bedridden and ambulatory (AOR=3.3;95%CI:1.70,6.29 and AOR=8.2;95%CI:4.34,15.64),respectively and TB history in the family (AOR=3.00; 95%CI:1.57,5.74) were predictors for TB infection. Taking CPT (AOR=0.36; 95%CI: 0.21, 0.62) and having early WHO clinical stage I or II (AOR=0.34; 95%CI: 0.20, 0.56) had protective effect against TB infection. Conclusion &Recommendation Behavioral, biological, clinical and TB history in the family were highly prevalent in the study area. Strengthen screening more frequently, CPT Prophlaxysis and treated promptly important to reduce TB co-morbidity.


2020 ◽  
Author(s):  
Habtamu Belew Mera ◽  
Moges Wubie ◽  
Getaye Tizazu ◽  
Abebaw Bitew ◽  
Tesfa Birlew

Abstract Background: Tuberculosis is a serious health risk, for people living with human immune deficiency virus worldwide, and the burden of TB/HIV infection is still high in Ethiopia in particular. Therefore, the aim of this study was to determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam Zone, northwest, Ethiopia. Methods: Institution based unmatched case-control study was employed to determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam Zone, Northwest, Ethiopia from March 7-April 15, 2017. A total of 552 participants were participated in the study (139 Cases and 413 controls). Cases were confirmed with active TB and infected HIV, and controls were HIV positive adults with non-TB. All cases in each health facility who confirmed by acid-fast bacilli, culture and gene expert were considered as TB positive. However, controls were selected by using simple random sampling technique through the above diagnostic criteria and the data were collected with Face to face interview as well as patient medical record were utilized, and the quality of the data were assured, checked, coded, cleaned and entered in EPI-Data version 3.1 and exported to SPSS version 20 for the analysis. Result: Of the total sample (556), just about 552(99.2%) were participated in the study among this 47.5% were females and 58.9% were rural. Behavioral and modifiable biological risk factors: alcohol users (AOR=2.33; 95%CI:1.34,4.07),BMI<18.5kg/m2 (AOR=3.03;95%CI:1.79,5.14), CD4 count ≤200 cells/µl (AOR=2.34;95%CI:1.89,2.79) and between 201-499 cells/µl (AOR=2.63; 95%CI: 1.01,6.84), bedridden and ambulatory (AOR=3.3;95%CI:1.70,6.29 and AOR=8.2;95%CI:4.34,15.64),respectively. TB history in the family (AOR=3.00; 95%CI: 1.57, 5.74) were predictors for TB infection. Taking CPT (AOR=0.36; 95%CI: 0.21, 0.62) and having early WHO clinical stage I or II (AOR=0.34; 95%CI: 0.20, 0.56) had protective effect against TB infection. Conclusion: From this study, it has been concluded that alcohol users, BMI<18.5kg/m², CD4 count <499 cells/µl, bedridden and ambulatory and TB history were highly associated in TB-HIV co-infected adults. Strengthen screening more frequently, CPT Prophlaxysis and treated promptly important to reduce TB co-morbidity.


2020 ◽  
Author(s):  
Habtamu Belew Mera ◽  
Moges Wubie ◽  
Getaye Tizazu ◽  
Abebaw Bitew ◽  
Tesfa Birlew

Abstract Introduction: Tuberculosis is a serious health risk, for people living with human immune deficiency virus worldwide, and the burden of TB/HIV infection is still high in Ethiopia in particular. Therefore, the aim of this study was to determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam Zone, northwest, Ethiopia. Methods and Materials: Institution based unmatched case-control study was employed to determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in east and west Gojjam, Northwest, Ethiopia from March 7-April 15, 2017. A total of 552 participants were participated in the study (139 Cases and 413 controls). Cases were confirmed with active TB and infected with HIV, and controls were HIV positive adults with non-TB. All cases in each health facility who confirmed by acid-fast bacilli, culture and gene expert were considered as TB positive. However, controls were selected by using simple random sampling technique through the above diagnostic criteria and the data were collected with Face to face interview as well as patient medical record were utilized, and the quality of the data were assured, checked, coded, cleaned and entered in EPI-Data version 3.1 and exported to SPSS version 20 for the analysis. Result: Of the total sample (556), just about 552(99.2%) were participated in the study. 47.5% were females and 58.9% were rural dweller. Behavioral and modifiable biological risk factors: alcohol users (AOR=2.33; 95%CI:1.34,4.07),BMI<18.5kg/m2 (AOR=3.03;95%CI:1.79,5.14), CD4 count ≤200 cells/µl (AOR=2.34;95%CI:1.89,2.79) and between 201-499 cells/µl (AOR=2.63; 95%CI: 1.01,6.84), bedridden and ambulatory (AOR=3.3;95%CI:1.70,6.29 and AOR=8.2;95%CI:4.34,15.64),respectively. TB history in the family (AOR=3.00; 95%CI: 1.57, 5.74) were predictors for TB infection. Taking CPT (AOR=0.36; 95%CI: 0.21, 0.62) and having early WHO clinical stage I or II (AOR=0.34; 95%CI: 0.20, 0.56) had protective effect against TB infection. Conclusion: From this study, it has been concluded that alcohol users, BMI<18.5kg/m², CD4 count <499 cells/µl, bedridden and ambulatory and TB history were highly associated in TB-HIV co-infected adults. Strengthen screening more frequently, CPT Prophlaxysis and treated promptly important to reduce TB co-morbidity.


2021 ◽  
Vol Volume 13 ◽  
pp. 191-196
Author(s):  
Tadesse Asmamaw Dejenie ◽  
Worku Mamo Degu ◽  
Setognal Birara Aychiluhm ◽  
Endeshaw Chekol Abebe ◽  
Markeshaw Tiruneh G/Medhin

2018 ◽  
Vol 2018 ◽  
pp. 1-8 ◽  
Author(s):  
Addisu Tesfaw ◽  
Dube Jara ◽  
Habtamu Temesgen

Introduction. Dietary diversity is defined as the amount of different food groups or foods that are consumed over a specific reference time. The human immune deficiency virus problem remains one of the main public health challenges, especially in low and middle income countries. Nutrition has been linked to both the transmission of human immune deficiency virus and poor outcomes related to human immune deficiency virus. Objective. To assess dietary diversity and associated factors among human immune deficiency virus positive adult patients in Motta administrative town, Northwest Ethiopia, 2017. Methods. A facility based cross-sectional study design was conducted on 410 study participants selected using a stratified sampling technique with proportional allocation. The data were collected using semi-structured and pretested questionnaire. Data were entered into Epi-Data version 3.1 and analysis was performed using SPSS version 20. Descriptive statistics were used to describe the number and percentage of the study variables. The bivariate and multivariable logistic regression analyses were done to identify the independent factors associated with dietary diversity among adult human immune virus (HIV) positive patients. Result. A total of 410 study participants were included in the analysis. Of the total, 121 (29.5%) of adult HIV positive respondents consumed diversified diet with the mean dietary diversity score of 3.2 (SD±1.88). The predominant food item consumed during the study periods was starchy staples (96.1%) and legumes (81.7%). Having means of communication cell phone (mobile phone) [(AOR= 2.13 (1.16, 3.60)], media exposure status in the household [(AOR =1.95 (1.22, 3.11)] and nutrition counselling [(AOR =2.17 (1.09, 4.67)] were significant factors associated with dietary diversified feeding at 95% CI. Conclusion. The study revealed that low dietary diversity score was significant nutritional problem among HIV positive adults in Motta town health facilities. Having mobile cell phone, media exposure status and nutritional counseling were significantly associated with dietary diversity score. Therefore efforts should be strengthened to improve the counseling service at each health institution and encourage the patients to use media for the source of information.


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