scholarly journals Predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam zone, northwest, Ethiopia, 2017

2020 ◽  
Author(s):  
Habtamu Belew Mera ◽  
Moges Wubie ◽  
Getaye Tizazu ◽  
Abebaw Bitew ◽  
Tesfa Birlew
Keyword(s):  
Northwest Ethiopia ◽  
Cd4 Count ◽  
Tuberculosis Infection ◽  
Treatment Center ◽  
Human Immune Deficiency Virus ◽  
Co Morbidity ◽  
West Gojjam ◽  
East And West ◽  
Alcohol Users ◽  
West Gojjam Zone

Abstract Background: Tuberculosis is a serious health risk, for people living with human immune deficiency virus worldwide, and the burden of TB/HIV infection is still high in Ethiopia in particular. Therefore, the aim of this study was to determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam Zone, northwest, Ethiopia. Methods: Institution based unmatched case-control study was employed to determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam Zone, Northwest, Ethiopia from March 7-April 15, 2017. A total of 552 participants were participated in the study (139 Cases and 413 controls). Cases were confirmed with active TB and infected HIV, and controls were HIV positive adults with non-TB. All cases in each health facility who confirmed by acid-fast bacilli, culture and gene expert were considered as TB positive. However, controls were selected by using simple random sampling technique through the above diagnostic criteria and the data were collected with Face to face interview as well as patient medical record were utilized, and the quality of the data were assured, checked, coded, cleaned and entered in EPI-Data version 3.1 and exported to SPSS version 20 for the analysis. Result: Of the total sample (556), just about 552(99.2%) were participated in the study among this 47.5% were females and 58.9% were rural. Behavioral and modifiable biological risk factors: alcohol users (AOR=2.33; 95%CI:1.34,4.07),BMI<18.5kg/m2 (AOR=3.03;95%CI:1.79,5.14), CD4 count ≤200 cells/µl (AOR=2.34;95%CI:1.89,2.79) and between 201-499 cells/µl (AOR=2.63; 95%CI: 1.01,6.84), bedridden and ambulatory (AOR=3.3;95%CI:1.70,6.29 and AOR=8.2;95%CI:4.34,15.64),respectively. TB history in the family (AOR=3.00; 95%CI: 1.57, 5.74) were predictors for TB infection. Taking CPT (AOR=0.36; 95%CI: 0.21, 0.62) and having early WHO clinical stage I or II (AOR=0.34; 95%CI: 0.20, 0.56) had protective effect against TB infection. Conclusion: From this study, it has been concluded that alcohol users, BMI<18.5kg/m², CD4 count <499 cells/µl, bedridden and ambulatory and TB history were highly associated in TB-HIV co-infected adults. Strengthen screening more frequently, CPT Prophlaxysis and treated promptly important to reduce TB co-morbidity.

scholarly journals Predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in east and west Gojjam, northwest, Ethiopia, 2017

2020 ◽  
Author(s):  
Habtamu Belew Mera ◽  
Moges Wubie ◽  
Getaye Tizazu ◽  
Abebaw Bitew ◽  
Tesfa Birlew
Keyword(s):  
Clinical Stage ◽  
Northwest Ethiopia ◽  
Cd4 Count ◽  
Tuberculosis Infection ◽  
Treatment Center ◽  
Human Immune Deficiency Virus ◽  
Co Morbidity ◽  
West Gojjam ◽  
East And West ◽  
Alcohol Users

Abstract Introduction: Tuberculosis is a serious health risk, for people living with human immune deficiency virus worldwide, and the burden of TB/HIV infection is still high in Ethiopia in particular. Therefore, the aim of this study was to determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam Zone, northwest, Ethiopia. Methods and Materials: Institution based unmatched case-control study was employed to determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in east and west Gojjam, Northwest, Ethiopia from March 7-April 15, 2017. A total of 552 participants were participated in the study (139 Cases and 413 controls). Cases were confirmed with active TB and infected with HIV, and controls were HIV positive adults with non-TB. All cases in each health facility who confirmed by acid-fast bacilli, culture and gene expert were considered as TB positive. However, controls were selected by using simple random sampling technique through the above diagnostic criteria and the data were collected with Face to face interview as well as patient medical record were utilized, and the quality of the data were assured, checked, coded, cleaned and entered in EPI-Data version 3.1 and exported to SPSS version 20 for the analysis. Result: Of the total sample (556), just about 552(99.2%) were participated in the study. 47.5% were females and 58.9% were rural dweller. Behavioral and modifiable biological risk factors: alcohol users (AOR=2.33; 95%CI:1.34,4.07),BMI<18.5kg/m2 (AOR=3.03;95%CI:1.79,5.14), CD4 count ≤200 cells/µl (AOR=2.34;95%CI:1.89,2.79) and between 201-499 cells/µl (AOR=2.63; 95%CI: 1.01,6.84), bedridden and ambulatory (AOR=3.3;95%CI:1.70,6.29 and AOR=8.2;95%CI:4.34,15.64),respectively. TB history in the family (AOR=3.00; 95%CI: 1.57, 5.74) were predictors for TB infection. Taking CPT (AOR=0.36; 95%CI: 0.21, 0.62) and having early WHO clinical stage I or II (AOR=0.34; 95%CI: 0.20, 0.56) had protective effect against TB infection. Conclusion: From this study, it has been concluded that alcohol users, BMI<18.5kg/m², CD4 count <499 cells/µl, bedridden and ambulatory and TB history were highly associated in TB-HIV co-infected adults. Strengthen screening more frequently, CPT Prophlaxysis and treated promptly important to reduce TB co-morbidity.

scholarly journals Predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and West Gojjam Zone, northwest, Ethiopia, 2017

2019 ◽  
Author(s):  
Habtamu Belew Mera ◽  
Moges Wubie ◽  
Getaye Tizazu ◽  
Abebaw Bitew ◽  
Tesfa Birlew
Keyword(s):  
Immune Deficiency ◽  
Northwest Ethiopia ◽  
Tuberculosis Infection ◽  
Treatment Center ◽  
Human Immune Deficiency Virus ◽  
The Family ◽  
West Gojjam ◽  
Human Immune ◽  
East And West ◽  
West Gojjam Zone

Abstract Background: Tuberculosis is a serious health threat, especially for people living with human immune deficiency virus worldwide and the burden of TB/HIV infection is still high in Ethiopia in particular. Objective: To determine the predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in East and west Gojjam, Northwest Ethiopia, 2017Methods: An institution based unmatched case-control study was conducted in East and West Gojjam Zone, Northwest, Ethiopia from March 7-April 15, 2017. Cases were 139 tuberculosis infected human immune deficiency virus positives and controls were 413 non-TB infected HIV positives i.e. 1:3 proportion. All cases in each health facility who confirmed by acid-fast bacilli (direct microscopy), culture and gene expert were considered as TB positive fine needle aspiration. However controls were selected by using simple random sampling technique through the above diagnostic criteria and the data were collected with Face to face interview as well as patient medical record were used and the quality of the data were assured, checked, coded, cleaned and entered in EPI-Data version 3.1 and exported to SPSS version 20 for the analysis. Result: Of the total sample (556), just about 552(99.2%) were participated in the study among this 47.5% were females and 58.9% were rural. Behavioral and modifiable biological risk factors: alcohol users (AOR=2.33; 95% CI:1.34,4.07), BMI<18.5kg/m2 (AOR=3.03;95%CI:1.79,5.14), CD4 count ≤200 cells/µl (AOR=2.34;95%CI:1.89,2.79) and between 201-499 cells/µl (AOR=2.63; 95%CI: 1.01,6.84), bedridden and ambulatory (AOR=3.3;95%CI:1.70,6.29 and AOR=8.2;95%CI:4.34,15.64),respectively. TB history in the family (AOR=3.00; 95%CI: 1.57, 5.74) were predictors for TB infection. Taking CPT (AOR=0.36; 95%CI: 0.21, 0.62) and having early WHO clinical stage I or II (AOR=0.34; 95%CI: 0.20, 0.56) had protective effect against TB infection. Conclusion &Recommendation: Behavioral, biological, clinical and TB history in the family were highly prevalent in the study area. Strengthen screening more frequently, CPT Prophlaxysis and treated promptly important to reduce TB co-morbidity.

scholarly journals Predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in east and west Gojjam, northwest, Ethiopia, 2017

2019 ◽  
Author(s):  
Habtamu Belew Mera ◽  
Moges Wubie ◽  
Getaye Tizazu ◽  
Abebaw Bitew ◽  
Tesfa Birlew
Keyword(s):  
Immune Deficiency ◽  
Northwest Ethiopia ◽  
Tuberculosis Infection ◽  
Treatment Center ◽  
Human Immune Deficiency Virus ◽  
Co Morbidity ◽  
The Family ◽  
West Gojjam ◽  
Human Immune ◽  
East And West

Abstract Background Tuberculosis is a serious health threat, especially for people living with human immune deficiency virus and is more likely than others to become sick with tuberculosis are. Objective Predictors of tuberculosis infection among adults visiting anti-retroviral treatment center in Gojjam, Northwest Ethiopia, 2017 Methods An institution based unmatched case-control study was conducted in East and West Gojjam Zone, Northwest, Ethiopia from March 7-April 15, 2017. Cases were 139 tuberculosis infected human immune deficiency virus positives and controls were 413 non-TB infected HIV positives i.e. 1:3 proportion. All cases in each health facility were included. but controls were selected by using simple random sampling technique and the data were collected with Face to face interview as well as patient medical record were used and the quality of the data were assured, the data were checked, coded, cleaned and entered in EPI-Data version 3.1 and exported to SPSS version 20 for the analysis. Result of the total sample (556), just about 552(99.2%) were participated in the study (female=47.5% and rural=58.9%). Behavioral and modifiable biological risk factors: alcohol users (AOR=2.33; 95% CI:1.34,4.07), BMI<18.5kg/m2 (AOR=3.03;95%CI:1.79,5.14), CD4 count ≤200 cells/µl (AOR=2.34;95%CI:1.89,2.79) and between 201-499 cells/µl (AOR=2.63; 95%CI: 1.01,6.84), bedridden and ambulatory (AOR=3.3;95%CI:1.70,6.29 and AOR=8.2;95%CI:4.34,15.64),respectively and TB history in the family (AOR=3.00; 95%CI:1.57,5.74) were predictors for TB infection. Taking CPT (AOR=0.36; 95%CI: 0.21, 0.62) and having early WHO clinical stage I or II (AOR=0.34; 95%CI: 0.20, 0.56) had protective effect against TB infection. Conclusion &Recommendation Behavioral, biological, clinical and TB history in the family were highly prevalent in the study area. Strengthen screening more frequently, CPT Prophlaxysis and treated promptly important to reduce TB co-morbidity.

scholarly journals Anaemia Associated with Trypanosomes Infections in Cattle of West Gojjam Zone, Northwest Ethiopia

2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Kumela Lelisa ◽  
Behablom Meharenet
Keyword(s):  
Parasitic Infection ◽  
Positive Association ◽  
Northwest Ethiopia ◽  
Buffy Coat ◽  
Trypanosome Infection ◽  
Large Area ◽  
Cross Sectional ◽  
West Gojjam ◽  
The Mean ◽  
West Gojjam Zone

Background. African animal trypanosomosis is a major veterinary problem over a large area of the tsetse belt region of Africa. Anaemia is a cardinal sign of trypanosome infections. The mechanism of anaemia due to trypanosomosis is complex and multifactorial in origin. Packed cell volume (PCV) usually gives an indication of the anaemia and disease status of a trypanosome-infected animal. Methods. A cross-sectional study was conducted from December 2017 to January 2018 in West Gojjam zone, Northwest Ethiopia, to determine the trypanosome infections rate and the possible correlation between parasitic infection and anaemia using the dark ground buffy coat technique, Giemsa-stained thin blood smear, and PCV reading on a haematocrit reader. Results. The overall trypanosomosis prevalence was 7.81%, 95% CI = 7.45–8.17. Trypanosoma congolense (4.25%) and T. vivax (3.56%) were the trypanosomes species identified in the studied area. PCV for all sampled cattle was analysed to estimate the degree of anaemia. From the total examined animals (N = 730), 356 (48.77%) were anaemic and 374 (51.23%) were nonanaemic. The mean PCV of parasitemic cattle was significantly lower (21.09%, 95% CI = 20.13–22.05) than that of aparasitemic ones (25.96%, 95% CI = 25.68–26.24). There was a positive association between trypanosome infection and anaemia. Although both trypanosome species are significantly associated with a decreased herd mean PCV (<24), the mean PCV of cattle infected with T. congolense (19.45%) was lower than that of infected with T. vivax (23.04%). The herd mean PCV was not significantly associated to locations, age, and sex of the studied animals. Conclusions. The study confirms that the prevalence of trypanosomes infections and herd mean PCV has a significant association. The mean herd PCV can be a useful cheap tool to screen for possible trypanosome infection. However, there were cattle positive for trypanosomes having mean PCV within the reference interval and negative animals with anaemia. Furthermore, PCV reading should be confirmed by other diagnostic techniques to accurately conclude that trypanosomosis is the only cause of anaemia.

scholarly journals Dietary practices and associated factors among pregnant women in West Gojjam Zone, Northwest Ethiopia

2019 ◽  
Author(s):  
Yeshalem Mulugeta ◽  
Getu Degu Alem ◽  
Tefera Belachew
Keyword(s):  
Focus Group ◽  
Pregnant Women ◽  
Qualitative Data ◽  
Group Discussion ◽  
Northwest Ethiopia ◽  
Group Discussions ◽  
Dietary Practices ◽  
Key Informant ◽  
West Gojjam ◽  
West Gojjam Zone

Abstract Background: Optimal dietary practice is a critical requisite for maternal nutrition. However, the majority of Ethiopian pregnant women have inadequate nutrient intakes. These may be due to their poor dietary habits. Identifying factors affecting the dietary practices of pregnant women is crucial to design appropriate interventions. In this country, the dietary practices of pregnant women and determinants are not well studied. Therefore, the purpose of this study was to assess the dietary practices and associated factors among pregnant women in West Gojjam Zone, Northwest Ethiopia. Methods: A community-based cross-sectional study was carried out among 712 pregnant women from May to August 2018. Quantitative data complemented with a qualitative method. Pregnant women were selected using a cluster sampling technique. Structured questionnaires were utilized for data collection. Data were entered into Epi-Info version 7.2.2 and exported to SPSS version 23 software for analysis. Data were described using frequencies and mean. A logistic regression analysis was done. For the qualitative data, three focus group discussions and 17 key-informant interviews were conducted. Focus group discussion participants were mothers, husbands and health professionals. Typical case and homogeneous sampling techniques were used for the key-informant interviews and focus group discussions, respectively. Qualitative data were collected using interview and focus group discussion guides. Thematic analysis was used for the qualitative data. Results: Only 19.9% of respondents had appropriate dietary practices. On the multivariable logistic regression analyses, being food secure [AOR=2.25, 95% CI: (1.1, 4.5)], having high edible crop production [AOR=2.00, 95% CI: (1.2, 3.2)] and favorable attitude [AOR=1.69, 95% CI: (1.1, 2.6)] were significantly associated with the appropriate dietary practices of pregnant women. In the qualitative study lack of knowledge on maternal diet, cultural prohibition and knowledge gap of professionals were barriers that interfere with dietary practices during pregnancy. Conclusion: Pregnant women in the study area are found to have suboptimal dietary practices. Therefore, health professionals should give regular nutrition counseling using cards and role models for promoting diversified food production and consumption to meet the nutrient requirements during pregnancy.

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