scholarly journals Fluoride Concentration in Ground Water and Prevalence of Dental Fluorosis in Ethiopian Rift Valley: Systematic Review and Meta-Analysis

2019 ◽  
Author(s):  
Habtamu Demelash Enyew ◽  
Abebe Hailu Beyene ◽  
Zewdu Abebe ◽  
Addisu Dagnaw Melese

Abstract Background High fluoride concentrations in ground water is a serious health, social and economic problem in developing countries. The Ethiopian Rift Valley is associated with high fluoride levels in ground water where deep wells are the major source of drinking water supply. Many epidemiological studies on fluoride concentration and its adverse effects have been carried out. However, the result is scattered in different studies which needs systematically summarized for utilization.Objective The aim of this research is to estimate the pooled level of fluoride concentration in ground water and the prevalence of dental fluorosis in Ethiopian rift valley.Methods MEDLINE/PubMed, Cochrane library and Google scholar databases were systematically searched for studies reporting the mean concentration of fluoride in ground water and prevalence of dental fluorosis in Ethiopian Rift valley. We identified search terms by extracting key terms from reviews and selected relevant papers and review medical subject headings for relevant and appropriate terms.Results The mean concentration of fluoride in ground water and the prevalence of dental fluorosis were pooled from eleven and nine primary studies conducted in Ethiopian Rift Valley respectively. The pooled mean concentration of fluoride in ground water therefore was 6.03 mg/l (95% CI; 4.72–7.72, p < 0.001) and the pooled prevalence of dental fluorosis among residents in Ethiopian rift valley was 32% (95% CI: 25, 39%, p<0.001), 29% (95% CI: 22, 36%, p<0.001) and 24% (95% CI: 17, 32%, p<0.001 for mild, moderate and sever fluorosis respectively. The overall prevalence of dental fluorosis is 28% (95% CI: 24, 32%, p<0.001).Conclusions The mean concentration of fluoride in ground water in Ethiopian rift valley is nearly four times greater than the WHO guideline (1.5mg/l). Relatively high-level pooled prevalence of dental fluorosis was also seen in Ethiopian rift valley. Therefore, further studies covering the temperature, exposure time and other intake path ways including diet with large sample size is recommended. Interventional projects should conduct to decrease the concentration of fluoride in the ground drinking water source.

2019 ◽  
Author(s):  
Habtamu Demelash Enyew ◽  
Abebe Hailu Beyene ◽  
Zewdu Abebe ◽  
Addisu Dagnaw Melese

Abstract Background: The concentration of fluoride in ground drinking water greater than the world health organization standard value imposes a serious health, social and economic problem in developing countries. In the Ethiopian Rift Valley where deep wells are the major source of drinking water, high fluoride level is expected. Though many epidemiological studies on fluoride concentration and its adverse effects have been conducted in the region, the result is highly scattered and needs systematically summarized for better utilization. Objective: This research is aimed at estimating the pooled level of fluoride concentration in ground drinking water and the prevalence of dental fluorosis among Ethiopian rift valley residences. Methods: Cochrane library, MEDLINE/PubMed and Google scholar databases were searched for studies reporting the mean concentration of fluoride in ground water and prevalence of dental fluorosis in Ethiopian Rift valley. Search terms were identified by extracting key terms from reviews and selected relevant papers and review medical subject headings for relevant terms. Results: The mean fluoride level in ground water and the prevalence of dental fluorosis were pooled from eleven and nine primary studies conducted in Ethiopian Rift Valley respectively. The pooled mean level of fluoride in ground water therefore was 6.03 mg/l (95% CI; 4.72–7.72, p < 0.001) and the pooled prevalence of dental fluorosis among residents in Ethiopian rift valley was 32% (95% CI: 25, 39%, p<0.001), 29% (95% CI: 22, 36%, p<0.001) and 24% (95% CI: 17, 32%, p<0.001 for mild, moderate and sever dental fluorosis respectively. The overall prevalence of dental fluorosis is 28% (95% CI: 24, 32%, p<0.001). Conclusions: Though, the concentration level varies across different part of the rift valley region, still the level of fluoride in ground drinking water is greater than the WHO standard value (1.5mg/l). Relatively high-level pooled prevalence of dental fluorosis was also seen in Ethiopian rift valley. Therefore, further studies covering the temperature, exposure time and other intake path ways with large sample size is recommended. Interventional projects should be implemented to decrease the concentration of fluoride in the ground drinking water source. Key words: Dental fluorosis, Fluoride, Concentration, Rift Valley, Ethiopia


2019 ◽  
Author(s):  
Habtamu Demelash Enyew ◽  
Abebe Hailu Beyene ◽  
Zewdu Abebe ◽  
Addisu Dagnaw Melese

Abstract Background: The concentration of fluoride in ground drinking water greater than the world health organization standard value imposes a serious health, social and economic problem in developing countries. In the Ethiopian Rift Valley where deep wells are the major source of drinking water, high fluoride level is expected. Though many epidemiological studies on fluoride concentration and its adverse effects have been conducted in the region, the result is highly scattered and needs systematically summarized for better utilization. Objective: This research is aimed at estimating the pooled level of fluoride concentration in ground drinking water and the prevalence of dental fluorosis among Ethiopian rift valley residences. Methods: Cochrane library, MEDLINE/PubMed and Google scholar databases were searched for studies reporting the mean concentration of fluoride in ground water and prevalence of dental fluorosis in Ethiopian Rift valley. Search terms were identified by extracting key terms from reviews and selected relevant papers and review medical subject headings for relevant terms. Results: The mean fluoride level in ground water and the prevalence of dental fluorosis were pooled from eleven and nine primary studies conducted in Ethiopian Rift Valley respectively. The pooled mean level of fluoride in ground water therefore was 6.03 mg/l (95% CI; 4.72–7.72, p < 0.001) and the pooled prevalence of dental fluorosis among residents in Ethiopian rift valley was 32% (95% CI: 25, 39%, p<0.001), 29% (95% CI: 22, 36%, p<0.001) and 24% (95% CI: 17, 32%, p<0.001 for mild, moderate and sever dental fluorosis respectively. The overall prevalence of dental fluorosis is 28% (95% CI: 24, 32%, p<0.001). Conclusions: Though, the concentration level varies across different part of the rift valley region, still the level of fluoride in ground drinking water is greater than the WHO standard value (1.5mg/l). Relatively high-level pooled prevalence of dental fluorosis was also seen in Ethiopian rift valley. Therefore, further studies covering the temperature, exposure time and other intake path ways with large sample size is recommended. Interventional projects should be implemented to decrease the concentration of fluoride in the ground drinking water source. Key words: Dental fluorosis, Fluoride, Concentration, Rift Valley, Ethiopia


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Habtamu Demelash ◽  
Abebe Beyene ◽  
Zewdu Abebe ◽  
Addisu Melese

Abstract Background The concentration of fluoride in ground drinking water greater than the world health organization standard value imposes a serious health, social and economic problem in developing countries. In the Ethiopian Rift Valley where deep wells are the major source of drinking water, high fluoride level is expected. Though many epidemiological studies on fluoride concentration and its adverse effects have been conducted in the region, the result is highly scattered and needs systematically summarized for better utilization. Objective This research is aimed at estimating the pooled level of fluoride concentration in ground drinking water and the prevalence of dental fluorosis among Ethiopian rift valley residences. Methods Cochrane library, MEDLINE/PubMed and Google scholar databases were searched for studies reporting the mean concentration of fluoride in ground water and prevalence of dental fluorosis in Ethiopian Rift valley. Search terms were identified by extracting key terms from reviews and selected relevant papers and review medical subject headings for relevant terms. Results The mean fluoride level in ground water and the prevalence of dental fluorosis were pooled from eleven and nine primary studies conducted in Ethiopian Rift Valley respectively. The pooled mean level of fluoride in ground water therefore was 6.03 mg/l (95% CI; 4.72–7.72, p < 0.001) and the pooled prevalence of dental fluorosis among residents in Ethiopian rift valley was 32% (95% CI: 25, 39%, p < 0.001), 29% (95% CI: 22, 36%, p < 0.001) and 24% (95% CI: 17, 32%, p < 0.001 for mild, moderate and sever dental fluorosis respectively. The overall prevalence of dental fluorosis is 28% (95% CI, 24, 32%, p < 0.001). Conclusions Though, the concentration level varies across different part of the rift valley region, still the level of fluoride in ground drinking water is greater than the WHO standard value (1.5 mg/l). Relatively high-level pooled prevalence of dental fluorosis was also seen in Ethiopian rift valley. Therefore, further studies covering the temperature, exposure time and other intake path ways with large sample size is recommended. Interventional projects should be implemented to decrease the concentration of fluoride in the ground drinking water source.


2019 ◽  
Author(s):  
Biniyam Alemayehu Ayele ◽  
Yared Mamushet Yifru ◽  
Redda Tekle-Haimanot ◽  
Tewodros Rango Godebo

Abstract Background Fluorosis is endemic in many countries of Asia, South America, and Africa. In Africa, the countries located across the Great East African Rift Valley, including Ethiopia are a hotspot for fluorosis. While excessive and chronic exposure to fluoride causes dental and skeletal fluorosis, emerging studies have shown its adverse health effects in cognition, memory, learning and the function of central nervous system. The aim of this study is to assess neurological features of populations chronically exposed to a wide range of fluoride concentrations in drinking water wells in the Ethiopian Rift Valley.Method We conducted a study on 318 individuals living in rural villages located in fluoride endemic areas of the Ethiopian Rift Valley. Drinking water samples were collected from 23 community well sites, and analyzed for fluoride concentrations. Detailed clinical evaluations of skeletal fluorosis, neurologic history, and physical examination were performed in the study participants. Association between different fluoride concentrations and clinical features of fluorosis were done using chi square and crude odds ratio (OR).Results The mean age of the study participants was 28.0±14.9 years. Male accounted 55.7% of the subjects participated. About 80% of the participants were from the communities who used water from wells containing fluoride concentration >2 mg/L. The mean fluoride concentration in drinking water samples was 6.8±4.3 mg/L (range: 0.3 to 15.5 mg/L). Among the neurologic complications, headache, fatigue, and paresthesia accounted for 67%, 56.3%, and 37.5%, respectively. Impaired lumbar mobility, impaired squatting, impaired neck mobility, and knocked knee occurred in 22.3%, 6.6%, 2.2%, and 1.6%, respectively. Impaired lumbar mobility and kyphosis showed statistically significant association with higher fluoride concentration in drinking water (>2 mg/L) (P <0.05), while impaired squatting did not (p = 0.9) as compared to baseline fluoride concentration < 2mg/L.Conclusion Our findings strongly suggest that the adverse neurological and medical effects associated with prolonged exposure to elevated concentrations of fluoride in drinking water. We recommend conducting large scale epidemiological study in fluoride endemic areas using controlled population to better understand non-skeletal fluorosis related to neurological and medical complications.


Author(s):  
Atkeeya Tasneem ◽  
Tanvir Ahmed ◽  
Md. Khabir Uddin

Contamination of drinking water by Arsenic (As) & Iron (Fe) is nowadays appeared as a big concern for public health and environment as well. Immoderate and continued revelation of inorganic arsenic along with drinking water is triggering arsenicosis. High Fe and As concentration found in the study area is also appeared as very challenging to those people who are consuming the water on regular basis and they may confront to a high health risk. This study is conducted to determine the concentration of Fe and As in ground tube-well containing possible health risk in Bangladesh which examines the ground water As and Fe scenario of Singair Upazila, Manikganj district. Total 40 samples were collected from the study area. As and Fe were analyzed using Atomic Absorption Spectrophotometer (AAS). The study found As concentration ranged from 0.0011 to 0.0858 mg/L with the mean concentration as 0.04186 mg/L. Concentration of Fe was found 0.175 to 13.865 mg/L with the mean concentration as 3.600 mg/L whereas WHO standard level is 0.01 mg/L for As and 0.3 mg/l for Fe. It was also noticed that As and Fe concentration in shallow tube-well was relatively high than that in deep tube-well and a strong correlation between As and Fe was marked in the ground water. Therefore, to cope with this challenge, people should look for other sources or relocate the tube-well or treat the water for drinking and other everyday purposes.


2019 ◽  
Author(s):  
Biniyam Alemayehu Ayele ◽  
Yared Mamushet Yifru ◽  
Redda Tekle-Haimanot ◽  
Tewodros Rango Godebo

Abstract Background: Fluorosis is endemic in many countries of Asia, South America and Africa. In Africa, the countries located across the Great East African Rift Valley, including Ethiopia are a hotspot for fluorosis. While excessive and chronic exposure to fluoride causes dental and skeletal fluorosis, emerging studies have shown its adverse health effects in cognition, memory, learning and the function of Central Nervous System. Method: We conducted a study on 318 individuals living in rural villages located in fluoride endemic areas of the Ethiopian Rift Valley. Drinking water samples were collected from 23 community well sites, and analyzed for fluoride concentrations. Detailed clinical evaluations of skeletal fluorosis, neurologic history, and physical examination were performed in the study participants. Results: The mean age of the study participants was 28.0±14.9 years. About 80% of the participants were from the communities with fluoride level >2 mg/L. The mean fluoride level in drinking water samples was 6.8±4.3 (range: 0.3 to 15.5 mg/L). Male accounted 55.7% of the subjects participated. Among the neurologic complications, headache, fatigue, and paresthesia accounted for 67%, 56.3%, and 37.5%, respectively. Urinary incontinence, muscle atrophy and crippling neuroflourosis were observed only in a few of our study participants (< 5%). Headache disorders had statistically significant association with high fluoride levels. Clinical anemia was observed in 49.7% of our study population. Conclusion: Fluorosis has significant socio-economic and psychological impacts on productive segment of a population. Unlike previously reported findings, where neurological complications were largely attributed to compressive radioculomyelopathy, this study highlighted toxic level of fluoride might also results in non-compressive neurological and medical complications. We therefore recommend conducting further large scale epidemiological study to confirm these findings.


Author(s):  
Chetram Meena ◽  
Suman Rathore ◽  
Supriya Dwivedi ◽  
Zaozianlungliu Gonmei ◽  
Toteja Gs ◽  
...  

Objective: The objective of the present study was carried out to explore the potential association between fluoride concentration in drinking water and severity of dental fluorosis (DF) in the children.Methods: The study of dental fluorosis (DF) in the children (6-14 years old) was conducted in the two blocks (a) Jamwaramgarh block ;Heerawala, Palera ,Nayabas, Saipur and Birasana, (b) Amber block; Jugalpura, Chitanukalan, Sunder ka bas, Peelwa and Sirsali of Jaipur district, Rajasthan, India of the study villages. Total 150, children were surveyed. The role of fluoride (F) levels in drinking water in the etiology of dental fluorosis (DF) and the cases of dental fluorosis (DF) in both dentitions and teeth were also assessed using DEAN’S classification. The fluoride (F) concentration in source of drinking water was estimated by fluoride (F) ion specific electrode (Thermo Scientific Orion Star A329, USA).Results: The F concentration in (Tube well and Hand pump) water ranges from 0.7 to 15.0 parts per million (ppm) in Jamwaramgarh block and 1.40 to 5. 10 parts per million (ppm) in Amber block. Prevalence of dental fluorosis (DF) 27 (36%) in Jamwaramgar block and 26 (34.66%) in Amber block out of 75 children were examined in each block. Significantly increase in levels of F in drinking water is positively correlated with dental fluorosis.Conclusion: This study finding has shown the relation of dental fluorosis (DF) to high fluoride (F) levels in drinking water sources. A higher fluoride (F) levels in source of drinking water is a major risk factor for dental fluorosis. In view of the severity of the problem the intake of calcium rich foods and defluoridation techniques may help reducing risk of dental fluorosis (DF) in the children. 


2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Saeed Shanbehzadeh ◽  
Marzieh Vahid Dastjerdi ◽  
Akbar Hassanzadeh ◽  
Toba Kiyanizadeh

This study was carried out to examine heavy metals concentration in water and sediment of upstream and downstream of the entry of the sewage to the Tembi River, Iran. Samples were collected from upstream and downstream and were analyzed for Cd, Cr, Cu, Fe, Pb, Ni, and Zn by atomic absorption spectrophotometer. The results indicated that the average concentration of the metals in water and sediment on downstream was more than that of upstream. The comparison of the mean concentrations of heavy metals in water of the Tembi River with drinking water standards and those in the water used for agriculture suggests that the mean concentration of Cu and Zn lies within the standard range for drinking water and the mean concentration of Mn, Zn, and Pb lies within the standard range of agricultural water. The highest average concentration on downstream for Pb in water and for Mn in sediment was 1.95 and 820.5 ppm, respectively. Also, the lowest average concentration on upstream was identified for Cd in water and sediment 0.07 and 10 ppm, respectively. With regard to the results, it gets clear that using the water for recreational purposes, washing, and fishing is detrimental to human health and the environment.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Nelly Molina Frechero ◽  
Leonor Sánchez Pérez ◽  
Enrique Castañeda Castaneira ◽  
Anastasio Oropeza Oropeza ◽  
Enrique Gaona ◽  
...  

Fluoride is ingested primarily through consuming drinking water. When drinking water contains fluoride concentrations >0.7 parts per million (ppm), consuming such water can be toxic to the human body; this toxicity is called “fluorosis.” Therefore, it is critical to determine the fluoride concentrations in drinking water. The objective of this study was to determine the fluoride concentration in the drinking water of the city of Durango. The wells that supply the drinking water distribution system for the city of Durango were studied. One hundred eighty-nine (189) water samples were analyzed, and the fluoride concentration in each sample was quantified as established by the law NMX-AA-077-SCFI-2001. The fluoride concentrations in such samples varied between 2.22 and 7.23 ppm with a 4.313 ± 1.318 ppm mean concentration. The highest values were observed in the northern area of the city, with a 5.001 ± 2.669 ppm mean value. The samples produced values that exceeded the national standard for fluoride in drinking water. Chronic exposure to fluoride at such concentrations produces harmful health effects, the first sign of which is dental fluorosis. Therefore, it is essential that the government authorities implement water defluoridation programs and take preventative measures to reduce the ingestion of this toxic halogen.


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