Transconjunctival Cryo-Assisted Extraction of Intraconal Cavernous Hemangioma

10.21203/rs.2.14177/v1 ◽

2019 ◽

Author(s):

Ayman E Abd El Ghafar ◽

Sameh M Saleh ◽

Ahmed S Elwehidy

Keyword(s):

Visual Acuity ◽

Optic Nerve ◽

Postoperative Complications ◽

Cavernous Hemangioma ◽

Effective Technique ◽

Safety And Efficacy ◽

Transconjunctival Approach ◽

Subconjunctival Hemorrhage ◽

Assisted Extraction ◽

Retrobulbar Hemorrhage

Abstract Background The aim of this study is to evaluate the safety and efficacy of transconjunctival cryo-assisted orbitotomy for extraction of intraconal cavernous hemangioma. Methods The study was performed at the Mansoura ophthalmic center, Mansoura University, Egypt from May 2015 to August 2018. It included 18 patients with orbital intraconal cavernous hemangioma. In all cases, preoperative orbital MRI with contrast was performed, transconjunctival approach was used and cryo-assisted extraction of the lesion was performed. Cases were followed for six months after surgery. Results This study included 18 patients with intraconal cavernous hemangioma, ten females (55.6%) and eight males (44.4%) with a mean age 35.6 years. All lesions were located in the intraconal space, eight cases (44.5%) were lateral to the optic nerve, four cases (22.2%) were above the optic nerve, and six cases (33.3%) were below the optic nerve. Postoperative complications included three cases (16.7%) that showed postoperative diplopia due to lateral rectus paresis that improved in all cases within six months, one case (5.6%) that showed postoperative retrobulbar hemorrhage and proptosis that resolved within two weeks without sequelae, and four cases (22.2%) that showed subconjunctival hemorrhage, which resolved within two weeks. Of the two cases with drop of visual acuity preoperative, one case (5.6%) showed improvement of visual acuity and one case (5.6%) did not improve. Conclusions Transconjunctival cryo-assisted extraction of intraconal cavernous hemangioma represents a safe more conservative and effective technique.

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Transconjunctival Cryo-Assisted Extraction of Intraconal Cavernous Hemangioma

10.21203/rs.2.14177/v2 ◽

2020 ◽

Author(s):

ayman el sayed abd el sayed ghafar ◽

Sameh M Saleh ◽

Ahmed S Elwehidy ◽

amr mahmoud awara

Keyword(s):

Optic Nerve ◽

Cavernous Hemangioma ◽

Institutional Review Board ◽

Resonance Imaging ◽

Transconjunctival Approach ◽

Institutional Review ◽

Assisted Extraction ◽

Registration Number ◽

Registration Date ◽

Retrobulbar Hemorrhage

Abstract Background: The aim of this study is to evaluate safety and efficacy of transconjunctival cryo-assisted orbitotomy for extraction of intraconal cavernous hemangioma.Methods: The study was performed at the Mansoura ophthalmic center, Mansoura University, Egypt from May 2017 to August 2018, It included 18 patients with orbital intraconal cavernous hemangioma. In all cases, preoperative orbital MRI(magnetic resonance imaging) with contrast was performed, transconjunctival approach was used and cryo-assisted extraction of the lesions was performed. Cases were followed for six months after surgery.Results: This study included 18 patients with intraconal cavernous hemangioma, ten females (55.6%) and eight males (44.4%) with a mean age 35.6 years. Eight cases (44.5%) were lateral to the optic nerve, four cases (22.2%) were above the optic nerve, and six cases (33.3%) were below the optic nerve. Postoperative complications included three cases (16.7%) with postoperative diplopia due to lateral rectus paresis that improved in all cases within six months, one case (5.6%) with postoperative retrobulbar hemorrhage and proptosis that resolved within two weeks without sequelae, and four cases (22.2%) showed subconjunctival hemorrhage which resolved within two weeks. Of the two cases with drop of visual acuity preoperative, one case (5.6%) showed improvement of and one case (5.6%) did not improve. Conclusions: Transconjunctival orbitotomy assisted by the use of the cryoprobe for excision of intraconal cavernous hemangioma represents a good approach with minor resolvable complicationsTrial registration: Mansoura institutional review board (IRB)registration number: R/17.05.26 registration date: 10/5/2017 Keywords: transconjunctival orbitotomy, cryo-assisted extraction of hemangioma, intraconal cavernous hemangioma.

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PsycARTICLES Now Includes the Full-Text of More Than 100 Scholarly and Professional Journals

PsycEXTRA Dataset ◽

10.1037/e515112014-001 ◽

2014 ◽

Keyword(s):

Full Text ◽

Professional Journals

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Full-text Online Access

Archives of Facial Plastic Surgery ◽

10.1001/archfaci.10.6.400 ◽

2008 ◽

Vol 10 (6) ◽

pp. 400-400

Keyword(s):

Full Text ◽

Online Access

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Optimization of Ultrasonic-Assisted Extraction of Embelin from Embelia ribes using Response Surface Methodology

Planta Medica ◽

10.1055/s-0033-1348615 ◽

2013 ◽

Vol 79 (10) ◽

Cited By ~ 1

Author(s):

M Mujeeb ◽

S Alam ◽

M Akhtar ◽

AK Najmi ◽

M Aqil ◽

...

Keyword(s):

Response Surface Methodology ◽

Response Surface ◽

Embelia Ribes ◽

Assisted Extraction ◽

Ultrasonic Assisted ◽

Ultrasonic Assisted Extraction

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The Bible in the spiritual culture of Kievan Rus

Ukrainian Religious Studies ◽

10.32420/1998.7.139 ◽

1998 ◽

pp. 46-52

Author(s):

S. V. Rabotkina

Keyword(s):

Full Text ◽

Spiritual Life ◽

The Bible ◽

Spiritual Culture ◽

Slavonic Language ◽

Long Time ◽

The Church

A huge place in the spiritual life of medieval Rusich was occupied by the Bible, although for a long time Kievan Rus did not know it fully. The full text of the Holy Scriptures appears in the Church Slavonic language not earlier than 1499.

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Innovative Extraction Techniques for the Optimum Extraction of Phenolic Compounds from Peanut Meal and Evaluation of Their Biological Activities

Advances in Nutrition & Food Science ◽

10.33140/anfs.04.02.2 ◽

2019 ◽

Vol 4 (2) ◽

Keyword(s):

Phenolic Compounds ◽

Carcinoma Cell ◽

Biological Activities ◽

Peanut Meal ◽

Ultrasound Assisted Extraction ◽

Carcinoma Cell Lines ◽

Assisted Extraction ◽

Phenolic Extract ◽

Ultrasound Assisted ◽

Water Ratio

There is a worldwide demand for phenolic compounds (PC) because they exhibit several biological activities. This work aimed at extracting phenolic compounds from peanut meal. The methods of extraction were mainly: conventional solvent extraction (traditional methods) and ultrasound assisted extraction (recent methods) and comparing their results. Peanut meal (PM) was prepared by defatting with n-hexane, and then extracted by the two previous methods. First, the conventional solvents used were 80% methanol, ethanol, acetone, isopropanol, and distilled water. Then studied Different parameters such as meal: water ratio, also the effect of temperature and the pH on the extraction process. Second, ultrasonic assisted extractions (USAE), the parameters investigated were temperature, time and speed of sonication. Finally, all the extracts were analyzed by HPLC for their phenolic contents. Results indicated that the highest extracted PC achieved by solvents was in distilled water where 1:100, Meal: Water ratio which extracted 40 mg PC / g PM at 30& 35°C. Highest extracted PC was achieved by alkaline medium at pH 12 more than acidic and neutral medium. While (USAE) at speed 8 ultrasonication and temperature 30ᵒC, extracted 49.2mg PC /g PM. Sothe ultrasound assisted extraction exhibited great influence on the extraction of phenolic compounds from peanut meal. The ultrasonic peanut extract was examined for its antioxidant, antimicrobial and anticarcinogenic activities. The antioxidant activity of PM phenolic extract prepared by ultrasonic technique, was measured by, β-carotene, and DPPH methods, and reducing antioxidant power. Results revealed values: 84.57, 57.72 and 5960 respectively. The PM extract showed different levels of antimicrobial activity against the pathogenic bacteria used. As for the anticarcinogenic effect PM phenolic extract most effective on inhibiting colon carcinoma and lung carcinoma cell lines with IC50 = 20.7 and 20.8 µ/ml., respectively. This was followed by intestinal carcinoma and liver carcinoma cell lines with IC50= 39.6 and 40.2µ/ml.

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