scholarly journals The body weight-walking distance product as a superior parameter in determining the VO2 on-kinetics in coronary artery disease

2019 ◽  
Author(s):  
Isadora S. Rocco ◽  
Walter J. Gomes ◽  
Hayanne O. Pauletti ◽  
Marcela Viceconte ◽  
Bruna C. Matos-Garcia ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Ventricular Dysfunction ◽  
Left Ventricular ◽  
The Body ◽  
Walking Distance ◽  
Walk Test ◽  
Artery Disease ◽  
Test Distance ◽  
6 Minute Walk Test ◽  
Minute Walk

Abstract Background The 6-minute walk test distance is frequently used to assess functional capacity of cardiac disease population. Nevertheless, anthropometric differences can confound or misestimate performance, which highlights the need for new parameters. This study aims to investigate the potential of the body weight-walking distance product (D.W), compared to 6-minute walk test distance, to predict exercise capacity measured by VO 2 on-kinetics in coronary artery disease (CAD) patients.Methods Cross-section study in a tertiary-care reference institution. Forty-six participants with multiarterial CAD with and without left ventricular dysfunction underwent a 6-minute walk test with simultaneous use of mobile telemetric cardiopulmonary monitoring to evaluate oxygen uptake (VO 2 ) on-kinetics and other cardiorespiratory responses.Results Perceived effort Borg for lower limb fatigue was only correlated with the D.W (p=0.007). The percent-predicted and actual distance were only modestly to moderately correlated with VO 2 on-kinetics (p<0.05). All the associations of VO 2 on-kinetics parameters were improved by showing a stronger correlation to the D.W (p<0.0001), which also had a larger effect size to identify differences between coronary disease patients compared to distance ( d =1.32 vs d =0.84).Conclusion The D.W demonstrates potential as a measure superior to the distance in determining VO 2 on-kinetics in participants with CAD with and without left ventricular dysfunction.

Abstract 13603: Utility of the 6-minute Walk Test in Coronary Artery Disease Screening Before Kidney Transplant

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Xingxing Cheng ◽  
Daniel J Watford ◽  
Hiroyuki Arashi ◽  
Jane C Tan ◽  
William F Fearon
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Kidney Transplant ◽  
Cardiac Death ◽  
Walk Test ◽  
Non Invasive ◽  
Cardiac Evaluation ◽  
Artery Disease ◽  
6 Minute Walk Test ◽  
Minute Walk

Introduction: Coronary artery disease (CAD) screening is a cornerstone of kidney transplant (KTx) evaluation, but existing approaches result in excess testing and low intervention rate. Hypothesis: We hypothesize that aerobic performance, based on a simple office test (the 6-minute walk test, 6MWT), may help risk stratify KTx candidates. Methods: We performed 6MWT in waitlisted patients who were nearing KTx. Results were used for frailty counselling and not for cardiac evaluation. CAD screening was done according to our center protocol: invasive angiogram for patients with long-standing diabetes mellitus (DM) and non-invasive testing for other patients with risk factors and at the evaluating transplant nephrologist’s discretion. We used subdistribution Cox regression and time-dependent receiver operator curve to evaluate time to CAD event (revascularization, myocardial infarction, waitlist removal for CAD, or cardiac death), treating waitlist removal for non-CAD and non-cardiac death as competing events. Results: Of the 360 patients, 200 and 161 patients had 6MWT results <400 meters and ≥400 meters (~4 metabolic equivalents), respectively. Patients with lower 6MWT results were older (59±10 vs 50±12 years) and more likely to be female (54% vs 34%), have DM (61% vs 33%) or known atherosclerotic disease (44% vs 22%), and have had prior cardiac evaluation (72% vs 61%). They were also more likely to exhibit cardiac symptom during 6MWT (36% vs 6%) and more likely to be censored due to waitlist removal for non-CAD reasons (follow-up 391±337 vs 541±277 days). 6MWT was not associated with CAD event (subdistribution hazard ratio 1.00 [0.90-1.10], 1-year area under the curve [AUC] 0.54). 196 patients had invasive (52%) or non-invasive (48%) CAD testing within 6 months of 6MWT: 6MWT did not predict the CAD test result (odds ratio 0.96 [0.81-1.14], AUC 0.54). Of the 94 patients who had concurrent non-invasive CAD testing, the 1-year AUC of 6MWT, symptom (at rest or during 6MWT), AST guidelines, or non-invasive testing for CAD event were 0.64, 0.52, 0.46 and 0.66 respectively. Conclusions: The 6MWT did not perform better in risk stratification for CAD events compared to a symptom- or risk factor-based approach.

scholarly journals Targeting Paretic Propulsion and Walking Speed With a Soft Robotic Exosuit: A Consideration-of-Concept Trial

2021 ◽  
Vol 15 ◽  
Author(s):  
Franchino Porciuncula ◽  
Teresa C. Baker ◽  
Dheepak Arumukhom Revi ◽  
Jaehyun Bae ◽  
Regina Sloutsky ◽  
...  
Keyword(s):  
Training Program ◽  
Walking Speed ◽  
Gait Training ◽  
Walking Distance ◽  
Walk Test ◽  
Long Distance ◽  
Trailing Limb Angle ◽  
Test Distance ◽  
6 Minute Walk Test ◽  
Minute Walk

Background: Soft robotic exosuits can facilitate immediate increases in short- and long-distance walking speeds in people with post-stroke hemiparesis. We sought to assess the feasibility and rehabilitative potential of applying propulsion-augmenting exosuits as part of an individualized and progressive training program to retrain faster walking and the underlying propulsive strategy.Methods: A 54-yr old male with chronic hemiparesis completed five daily sessions of Robotic Exosuit Augmented Locomotion (REAL) gait training. REAL training consists of high-intensity, task-specific, and progressively challenging walking practice augmented by a soft robotic exosuit and is designed to facilitate faster walking by way of increased paretic propulsion. Repeated baseline assessments of comfortable walking speed over a 2-year period provided a stable baseline from which the effects of REAL training could be elucidated. Additional outcomes included paretic propulsion, maximum walking speed, and 6-minute walk test distance.Results: Comfortable walking speed was stable at 0.96 m/s prior to training and increased by 0.30 m/s after training. Clinically meaningful increases in maximum walking speed (Δ: 0.30 m/s) and 6-minute walk test distance (Δ: 59 m) were similarly observed. Improvements in paretic peak propulsion (Δ: 2.80 %BW), propulsive power (Δ: 0.41 W/kg), and trailing limb angle (Δ: 6.2 degrees) were observed at comfortable walking speed (p's &lt; 0.05). Likewise, improvements in paretic peak propulsion (Δ: 4.63 %BW) and trailing limb angle (Δ: 4.30 degrees) were observed at maximum walking speed (p's &lt; 0.05).Conclusions: The REAL training program is feasible to implement after stroke and capable of facilitating rapid and meaningful improvements in paretic propulsion, walking speed, and walking distance.

scholarly journals 6-minute walking test in patients after cabg - assessment of exercise capacity

2015 ◽  
Vol 29 (2) ◽  
pp. 19-24 ◽  
Author(s):  
Joanna Wojtkowska ◽  
Izabela Wojtkowska ◽  
Jadwiga Wolszakiewicz
Keyword(s):  
Risk Factors ◽  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Exercise Tolerance ◽  
Disease Risk ◽  
Walk Test ◽  
6Mwt Distance ◽  
Artery Disease ◽  
6 Minute Walk Test ◽  
Minute Walk

Abstract Introduction: The 6-minute walk test is a well established diagnostic tool in clinical cardiology to determine exercise tolerance, prognostic measure, control and modify the implemented treatment. Aim: Assess exercise tolerance in patients with coronary artery disease after surgical coronary artery bypass grafting using 6-minute walk test in correlation with selected concomitant risk factors for coronary artery disease. Material and methods: Analysis of medical records of 100 randomly selected patients, diagnosed by coronary angiography and coronary heart disease, scheduled for CABG. Patients were evaluated using exercise tolerance as measured by 6MWT before and 12 months after CABG. The results were correlated with the selected risk factors. Results: The study group showed improvement in 6MWT distance of 43.17 m (± 104.41) at 12-months after CABG. In order to analyze which risk factors influenced the observed changes of the 6MWT distance, the obtained results were correlated with factors such as the age of patients, sex, hypertension and smoking. There was no effect of these parameters on shortening or lengthening the distance. Conclusions: 1. From selected coronary artery disease risk factors only hypertension adversely affected the 6MWT distance before CABG. 3. The CABG operation caused significant improvement of exercise tolerance in patients with worse baseline exercise tolerance.

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