scholarly journals Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study

2020 ◽  
Author(s):  
VINCENT MUBANGIZI ◽  
Samuel Maling ◽  
Celestino Obua ◽  
Alexander C. Tsai
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Population Based ◽  
Sub Saharan Africa ◽  
Cross Sectional ◽  
Population Based Study ◽  
Community Screening ◽  
Multi Stage ◽  
Multivariable Regression ◽  
Sub Saharan

Abstract Background: There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda. Methods: We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia. Results: Overall, 80(20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10-1.03, p˂0.001), having some education (AOR, 0.57; 95% CI, 0.41-0.81, p=0.001), exercise (AOR, 0.44; 95% CI, 0.27-0.72, p=0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24-0.77, p=0.001). Conclusions: In this population-based sample of older-age adults, nearly one-fifth screened positive for dementia. Key words: Alzheimer’s disease, dementia, Sub-Saharan Africa, Uganda

scholarly journals Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study

2019 ◽  
Author(s):  
VINCENT MUBANGIZI ◽  
Samuel Maling ◽  
Celestino Obua ◽  
Alexander C. Tsai
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Population Based ◽  
Cross Sectional ◽  
Population Based Study ◽  
Community Screening ◽  
Multi Stage ◽  
Multivariable Regression ◽  
Sub Saharan ◽  
Southwestern Uganda

Abstract Introduction There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa.Objective To estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda.Methods We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia.Results Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10-1.03, p˂0.001), having some education (AOR, 0.57; 95% CI, 0.41-0.81, p=0.001), exercise (AOR, 0.44; 95% CI, 0.27-0.72, p=0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24-0.77, p=0.001).Conclusion In this population-based sample of older-age adults, nearly one-fifth screened positive for dementia.

scholarly journals Prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda: cross-sectional, population-based study

2020 ◽  
Author(s):  
VINCENT MUBANGIZI ◽  
Samuel Maling ◽  
Celestino Obua ◽  
Alexander C. Tsai
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Population Based ◽  
Cross Sectional ◽  
Population Based Study ◽  
Community Screening ◽  
Multi Stage ◽  
Multivariable Regression ◽  
Sub Saharan ◽  
Southwestern Uganda

Abstract Introduction There is a paucity of data on the prevalence and correlates of Alzheimer’s disease and related dementias in sub-Saharan Africa.Objective To estimate the prevalence and correlates of Alzheimer’s disease and related dementias in rural Uganda.Methods We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia.Results Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10-1.03, p˂0.001), having some education (AOR, 0.57; 95% CI, 0.41-0.81, p=0.001), exercise (AOR, 0.44; 95% CI, 0.27-0.72, p=0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24-0.77, p=0.001).Conclusion In this population-based sample of older-age adults, nearly one-fifth screened positive for dementia.

scholarly journals Determinants of Restrictive Spirometric Pattern in a Sub-Saharan Urban Setting: A Cross-sectional Population-based Study

2016 ◽  
Vol 10 (1) ◽  
pp. 86-95 ◽  
Author(s):  
Eric Walter Pefura-Yone ◽  
Adamou Dodo Balkissou ◽  
Andre Pascal Kengne
Keyword(s):  
Heart Diseases ◽  
Population Based ◽  
Forced Expiratory Volume ◽  
Urban Setting ◽  
Sub Saharan Africa ◽  
Cross Sectional ◽  
History Of ◽  
Sub Saharan ◽  
And Control ◽  
Restrictive Pattern

Background Restrictive spirometric pattern is a risk factor for all-cause and cause-specific mortality. Objective We assessed the prevalence of restrictive pattern and investigated its determinants in a major sub-Saharan Africa city. Methods Participants were adults (≥ 19 years) who took part in a population-based survey in Yaounde (Cameroon) between December 2013 and April 2014. Restrictive pattern was based on a FVC below the lower limit of the normal (LLN) and a ratio forced expiratory volume in one second (FEV1)/FVC ≥ LLN (LLN-based restrictive pattern) or a FVC <80% and FEV1/FVC ≥ LLN (fixed cut-off based restrictive pattern). Determinants were investigated by logistic regressions. Results In all, 1003 participants [514 (51.2%) women] with a mean age of 33.7 years were included. The prevalence of restrictive pattern was 18.8% (95%CI: 16.6-21.2) based on LLN and 15.0% (13.0-17.2) based on fixed cut-off. LLN-based restrictive pattern was mild in 148 (78.3%) subjects, moderate in 35 (18.5%) and severe in 6 (3.2%). Determinants of LLN-based restrictive pattern were age ≥ 60 years [adjusted odds ratio 2.90 (95%CI 1.46-5.77), p=0.002), history of pulmonary tuberculosis [3.81(1.42-10.20), p=0.008], prevalent heart diseases [3.81 (1.20-12.12), p=0.024] and underweight [5.15(1.30-20.39), p=0.020]. Determinants were largely similar with slightly different effect sizes for fixed cut-off based restrictive pattern. Conclusion Restrictive pattern was very frequent in this city. Clinical implications These results enhance the needs to increase the efforts to prevent and control tuberculosis, cardiovascular diseases and underweight in this setting.

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